SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001369
Gene Symbol: DNAH5
Description: Homo sapiens dynein, axonemal, heavy chain 5 (DNAH5), mRNA.
Gene Location: chr5(-):13690436-13944589
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr5:g.13690385G>T COSN6864709 RK144_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4698 tttCATTTTGAaaagcaag
1
UCAAAAUG m8a Disrupted -0.133000 0.084000 0.010000
hsa-miR-548c-3p tttcATTTTTaaaagcaag
0 CAAAAAUC m6b Created no TS 0.049000 No effect
hsa-miR-607 tttcatTTTGAAaagcaag
3
GUUCAAAU m6b Disrupted -0.005000 no TS 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.13691629G>A COSN8203867 ASHPC_0001_Pa_P_2 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-15a-3p tctgttaacATGGCCTGgt
0 CAGGCCAU m8a (m7a->m8a) no TS -0.159000 0.010000
hsa-miR-4716-5p tctgttAACATGGcctggt
0 UCCAUGUU m7b Created no TS -0.088000 -0.150000
hsa-miR-4717-5p tctgttaacGTGGCCTggt
1
UAGGCCAC m7b (m7b->m6b) -0.201000 no TS 2.360000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.13691818T>A COSN2072266 RK064_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1297 tttTACTTGAttcatcatt
0 UUCAAGUA m7b (m6c->m7b) no TS -0.186000 -0.910000
hsa-miR-15b-3p ttttactTGATTCatcatt
0 CGAAUCAU m6b Created no TS -0.086000 No effect
hsa-miR-26a-5p tttTACTTGAttcatcatt
0 UUCAAGUA m7b (m6c->m7b) no TS -0.186000 -1.940000
hsa-miR-26b-5p tttTACTTGAttcatcatt
0 UUCAAGUA m7b (m6c->m7b) no TS -0.186000 -1.860000
hsa-miR-4465 tttTACTTGAttcatcatt
0 CUCAAGUA m7b (m6c->m7b) no TS -0.186000 -0.350000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.13691934T>C COSN2072268 RK029_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-32-3p agatCTAAATTattgtaac
0 CAAUUUAG m7b Disrupted -0.268000 -0.105000 1.180000
hsa-miR-32-3p agatCTAAATTattgtaac
0 CAAUUUAG m7b Disrupted -0.268000 -0.105000 1.180000
hsa-miR-32-3p agatCTAAATTattgtaac
0 CAAUUUAG m7b Disrupted -0.268 -0.105 1.18

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
13691938 rs199643112 T T hsa-miR-32-3p
hsa-miR-4760-5p
hsa-miR-7161-3p
hsa-miR-8061
2
2
2
2
aagatCTAAATTA
aagATCTAAAtta
AAGATCTAaatta
aagATCTAAAtta
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
-0.163
-0.084
-0.309
-0.081

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