| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
||||||||
| Home | Search | Help | Download | |||||
| RefSeq ID: | NM_021951 |
|---|---|
| Gene Symbol: | DMRT1 |
| Description: | Homo sapiens doublesex and mab-3 related transcription factor 1 (DMRT1), mRNA. |
| Gene Location: | chr9(+):841689-969090 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.968155G>A | COSN9318942 | 4132_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.968311G>C | COSN1383142 | HCC31T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.968363T>A | COSN1383143 | HCC4T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-126-5p |
gagtttaAATAATagtgtt |
2 |
CAUUAUUA | m6b | Disrupted | 0.041000 | no TS |
0.070000 |
|
| hsa-miR-4795-3p |
gagtttaAATAATAgtgtt |
2 |
AUAUUAUU | m7b | Disrupted | -0.059000 | no TS |
-0.210000 |
|
| hsa-miR-126-5p |
gagtttaAATAATagtgtt |
2 |
CAUUAUUA | m6b | Disrupted | 0.041000 | no TS |
0.070000 |
|
| hsa-miR-4795-3p |
gagtttaAATAATAgtgtt |
2 |
AUAUUAUU | m7b | Disrupted | -0.059000 | no TS |
-0.210000 |
|
| hsa-miR-126-5p |
gagtttaAATAATagtgtt |
2 |
CAUUAUUA | m6b | Disrupted | 0.041 | no TS |
0.07 |
|
| hsa-miR-4795-3p |
gagtttaAATAATAgtgtt |
2 |
AUAUUAUU | m7b | Disrupted | -0.059 | no TS |
-0.21 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.968716A>G | COSN6400006 | RK195_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-103a-2-5p |
taatcAGAAGCattaaagc |
0 | AGCUUCUU | m6b | Created | no TS | -0.127000 |
-0.020000 |
|
| hsa-miR-155-5p |
taatcagaAGCATTAAagc |
0 | UUAAUGCU | m8a | Created | no TS | -0.263000 |
-0.100000 |
|
| hsa-miR-3182 |
taatCAGAAGCattaaagc |
14 |
GCUUCUGU | m7a | Created | -0.193000 | -0.193000 |
-0.020000 |
|
| hsa-miR-33a-3p |
taatcagAAACATTaaagc |
0 | CAAUGUUU | m7b | Disrupted | -0.048000 | no TS |
0.590000 |
|
| hsa-miR-409-3p |
taatcagaAACATTaaagc |
0 | GAAUGUUG | m6b | Disrupted | -0.010000 | no TS |
0.020000 |
|
| hsa-miR-4307 |
taatcagAAACATTaaagc |
0 | AAUGUUUU | m7a | Disrupted | NA | NA |
0.740000 |
|
| hsa-miR-4762-3p |
taATCAGAAGcattaaagc |
0 | CUUCUGAU | m8a | (m7a->m8a) | -0.259000 | -0.157000 |
0.140000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.968839C>T | DMRT1_E5_UTR_3 | SJHYPO044_D | Hypodiploid_ALL | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-369-3p |
tgagttTATTATacattct |
0 | AAUAAUAC | m6b | Created | no TS | 0.026 |
-0.21 |
|
| hsa-miR-374a-5p |
tgagttTATTATAcattct |
0 | UUAUAAUA | m7b | Created | no TS | -0.051 |
-0.32 |
|
| hsa-miR-374b-5p |
tgagttTATTATAcattct |
0 | AUAUAAUA | m7b | Created | no TS | -0.051 |
-0.35 |
|
| hsa-miR-568 |
tgagtttaTTATACATtct |
0 | AUGUAUAA | m8a | Created | no TS | -0.132 |
-0.11 |
|
| hsa-miR-5692b |
tgagttTATTATacattct |
0 | AAUAAUAU | m6b | Created | no TS | 0.036 |
-0.02 |
|
| hsa-miR-5692c |
tgagttTATTATacattct |
0 | AAUAAUAU | m6b | Created | no TS | 0.036 |
-0.02 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr9:g.969078A>T | COSN9318944 | 4095_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3143 |
aaaAATGTTATtgatgact |
16 |
AUAACAUU | m8a | Disrupted | -0.133000 | no TS |
4.510000 |
| hsa-miR-3613-3p |
aaaaatgTTTTTGatgact |
0 | ACAAAAAA | m6b | Created | no TS | 0.015000 | No effect |
| hsa-miR-548ac |
aaaaatGTTTTTGatgact |
0 | CAAAAACC | m7a | Created | -0.042000 | -0.042000 |
-0.020000 |
| hsa-miR-548ae |
aaaaatGTTTTTGatgact |
0 | CAAAAACU | m7a | Created | NA | NA |
-2.150000 |
| hsa-miR-548ah-3p |
aaaaatGTTTTTGatgact |
0 | CAAAAACU | m7a | Created | NA | NA |
-1.660000 |
| hsa-miR-548am-3p |
aaaaatGTTTTTGatgact |
0 | CAAAAACU | m7a | Created | NA | NA |
-1.070000 |
| hsa-miR-548aq-3p |
aaaaatGTTTTTGatgact |
0 | CAAAAACU | m7a | Created | NA | NA |
-0.831000 |
| hsa-miR-548d-3p |
aaaaatGTTTTTGatgact |
0 | CAAAAACC | m7a | Created | -0.033000 | -0.033000 |
-0.010000 |
| hsa-miR-548h-3p |
aaaaatGTTTTTGatgact |
0 | CAAAAACC | m7a | Created | -0.051000 | -0.051000 |
-0.170000 |
| hsa-miR-548z |
aaaaatGTTTTTGatgact |
0 | CAAAAACC | m7a | Created | -0.051000 | -0.051000 |
-0.170000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 968516 | rs200312789 | - | T |
hsa-miR-5195-5p hsa-miR-548ac hsa-miR-548as-3p hsa-miR-548d-3p hsa-miR-548h-3p hsa-miR-548z hsa-miR-6771-3p |
0 |
TAGGGGTtttttt taggGGTTTTTtt tagGGGTTTTttt taggGGTTTTTtt taggGGTTTTTtt taggGGTTTTTtt taGGGGTTTtttt |
Unknown Unknown Unknown Unknown Unknown Unknown Unknown |
N N N N N N N |
-0.323 -0.013 -0.015 -0.022 -0.013 -0.013 -0.049 |
| G |
hsa-miR-4640-3p |
0 |
tAGGGGGTttttt |
Unknown |
N |
-0.372 |
|||
| 968516 | rs200698982 | - | TT |
hsa-miR-5195-5p hsa-miR-548ac hsa-miR-548as-3p hsa-miR-548d-3p hsa-miR-548h-3p hsa-miR-548z hsa-miR-6771-3p |
0 |
tTAGGGGTttttttt ttaggGGTTTTTttt ttagGGGTTTTtttt ttaggGGTTTTTttt ttaggGGTTTTTttt ttaggGGTTTTTttt ttaGGGGTTTttttt |
Unknown Unknown Unknown Unknown Unknown Unknown Unknown |
N N N N N N N |
-0.002 -0.002 -0.004 -0.002 -0.002 -0.002 -0.005 |
| - | |||||||||
| 968516 | rs34469209 | - | T |
hsa-miR-5195-5p hsa-miR-548ac hsa-miR-548as-3p hsa-miR-548d-3p hsa-miR-548h-3p hsa-miR-548z hsa-miR-6771-3p |
0 |
TAGGGGTtttttt taggGGTTTTTtt tagGGGTTTTttt taggGGTTTTTtt taggGGTTTTTtt taggGGTTTTTtt taGGGGTTTtttt |
Unknown Unknown Unknown Unknown Unknown Unknown Unknown |
N N N N N N N |
-0.002 -0.001 -0.003 -0.001 -0.001 -0.001 -0.003 |
| - | |||||||||
| 968645 | rs190005134 | G | G |
hsa-miR-338-5p |
2 |
tATATTGTgtgtg |
Disrupted |
N |
-0.021 |
| A |
hsa-miR-1277-5p hsa-miR-4789-3p hsa-miR-5692b hsa-miR-5692c |
2 2 2 2 |
TATATTAtgtgtg tatatTATGTGTg tATATTATgtgtg tATATTATgtgtg |
Created Created Created Created |
N N N N |
-0.018 -0.09 -0.001 -0.001 |