SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001164551
Gene Symbol: DISC1
Description: Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Lv, mRNA.
Gene Location: chr1(+):231762560-231886365
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr1:g.231750535T>C COSN1435528 RK049_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4257 ccaaggctCCTCTGagatt
4
CCAGAGGU m6b Created -0.107000 -0.236000 -2.240000
hsa-miR-5197-3p ccaaggCTCTTCTgagatt
2
AAGAAGAG m7b Disrupted -0.107000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr1:g.231750545A>T COSN5367382 RK015_C [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-216a tcTGAGATTAgtaatatat
1
UAAUCUCA m8a (m8a->m7a) -0.242000 -0.128000 1.820000
hsa-miR-4762-5p tctgAGATTTGtaatatat
0 CCAAAUCU m7b Created no TS -0.157000 0.370000
hsa-miR-520d-5p tctgagaTTTGTAatatat
0 CUACAAAG m6b Created no TS 0.000000 -0.020000
hsa-miR-524-5p tctgagaTTTGTAatatat
0 CUACAAAG m6b Created no TS 0.000000 -0.050000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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