| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_001164550 |
|---|---|
| Gene Symbol: | DISC1 |
| Description: | Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Lv, mRNA. |
| Gene Location: | chr1(+):231762560-231859820 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr1:g.231722748C>T | 0_5 | Melanoma | ||||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-4311 |
attcctcTCTCTTTtaaca |
6 |
GAAAGAGA | m7b | Created | no TS | -0.101 |
-0.29 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr1:g.231722924G>A | COSN15516617 | AOCS-135-8-X | [ovary][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3679-3p |
tgtaGGGGGAAGaaaccac |
0 | CUUCCCCC | m8a | Created | no TS | -0.307000 |
0.490000 |
| hsa-miR-4713-5p |
tgtagggGGGAGAAaccac |
0 | UUCUCCCA | m7a | Disrupted | -0.125000 | no TS |
0.330000 |
| hsa-miR-629-3p |
tgtagggGGGAGAAaccac |
0 | GUUCUCCC | m7b | Disrupted | -0.224000 | no TS |
-0.110000 |
| hsa-miR-3679-3p |
tgtaGGGGGAAGaaaccac |
0 | CUUCCCCC | m8a | Created | no TS | -0.307000 |
0.490000 |
| hsa-miR-4713-5p |
tgtagggGGGAGAAaccac |
0 | UUCUCCCA | m7a | Disrupted | -0.125000 | no TS |
0.330000 |
| hsa-miR-629-3p |
tgtagggGGGAGAAaccac |
0 | GUUCUCCC | m7b | Disrupted | -0.224000 | no TS |
-0.110000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr1:g.231722996C>T | COSN1099685 | HCC78T | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3667-5p |
cttcggaGGTCTTTaggac |
0 | AAAGACCC | m7a | Created | NA | NA |
-1.100000 |
| hsa-miR-4484 |
cttcggagGCCTTTaggac |
2 |
AAAAGGCG | m6b | Disrupted | -0.108000 | no TS |
0.210000 |
| hsa-miR-4509 |
cttcggaggCCTTTAGgac |
10 |
ACUAAAGG | m7b | (m7b->m6c) | -0.149000 | -0.060000 |
0.190000 |
| hsa-miR-4744 |
cttcggaggTCTTTAGgac |
9 |
UCUAAAGA | m7b | (m6c->m7b) | -0.229000 | -0.245000 |
-0.100000 |
| hsa-miR-548an |
cttcggagGCCTTTaggac |
2 |
AAAAGGCA | m6b | Disrupted | -0.066000 | no TS |
0.030000 |
| hsa-miR-548ao-3p |
cttcggaGGTCTTTaggac |
0 | AAAGACCG | m7a | Created | NA | NA | No effect |
| hsa-miR-548u |
cttcggagGTCTTTaggac |
0 | CAAAGACU | m6b | Created | no TS | -0.019000 | No effect |
| hsa-miR-3667-5p |
cttcggaGGTCTTTaggac |
0 | AAAGACCC | m7a | Created | NA | NA |
-1.1 |
| hsa-miR-4484 |
cttcggagGCCTTTaggac |
0 | AAAAGGCG | m6b | Disrupted | -0.108 | no TS |
0.21 |
| hsa-miR-4509 |
cttcggaggCCTTTAGgac |
0 | ACUAAAGG | m7b | (m7b->m6c) | -0.149 | -0.06 |
0.19 |
| hsa-miR-4744 |
cttcggaggTCTTTAGgac |
0 | UCUAAAGA | m7b | (m6c->m7b) | -0.229 | -0.245 |
-0.1 |
| hsa-miR-548an |
cttcggagGCCTTTaggac |
0 | AAAAGGCA | m6b | Disrupted | -0.066 | no TS |
0.03 |
| hsa-miR-548ao-3p |
cttcggaGGTCTTTaggac |
0 | AAAGACCG | m7a | Created | NA | NA | No effect |
| hsa-miR-548u |
cttcggagGTCTTTaggac |
0 | CAAAGACU | m6b | Created | no TS | -0.019 | No effect |