SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001164549
Gene Symbol: DISC1
Description: Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Lv, mRNA.
Gene Location: chr1(+):231762560-231907408
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr1:g.231771525G>C COSN15387109 AOCS-094-6-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-331-5p ttactggTACCTAaaatgt
0 CUAGGUAU m6b Created no TS -0.128000 -3.830000
hsa-miR-331-5p ttactggTACCTAaaatgt
0 CUAGGUAU m6b Created no TS -0.128000 -3.830000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.231771549A>T COSN5367390 RK030_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4761-5p gtgcttACCTTGTaccagg
0 ACAAGGUG m7a Created NA NA -0.280000
hsa-miR-548ag gtgcTTACCTTgtaccagg
0 AAAGGUAA m7b Created no TS -0.043000 -0.670000
hsa-miR-548ai gtgcTTACCTTgtaccagg
0 AAAGGUAA m7b Created no TS -0.070000 -3.850000
hsa-miR-570-5p gtgcTTACCTTgtaccagg
0 AAAGGUAA m7b Created no TS -0.070000 -3.850000
hsa-miR-624-3p gtgcttACCTTGTaccagg
0 CACAAGGU m7b Created no TS -0.304000 -3.960000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.231771624C>T COSN9061491 C0038T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-543 gaggaaaAATGTTTaagaa
0 AAACAUUC m7a Created NA NA -0.150000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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