SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_020946
Gene Symbol: DENND1A
Description: Homo sapiens DENN/MADD domain containing 1A (DENND1A), transcript variant 1, mRNA.
Gene Location: chr9(-):126141932-126692417
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr9:g.123379740G>A COSN8331640 SS6003111 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1206 ttcaCATGAACActgctgc
0 UGUUCAUG m8a Created no TS -0.269000 -0.740000
hsa-miR-124-5p ttcacaTGAACACtgctgc
0 CGUGUUCA m7b Created no TS -0.141000 -0.470000
hsa-miR-4255 ttcacatGAACACTGctgc
0 CAGUGUUC m8a Created no TS -0.168000 -0.760000

Mutation Mutation ID Sample Name Cancer Type
chr9:g.123380773C>T COSN8519940 J52_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-185-3p tgtgatacaCAGCCCCagc
8
AGGGGCUG m7b (m7b->m6b) -0.268000 -0.089000 -0.410000
hsa-miR-223-5p tgtgATACACagccccagc
1
CGUGUAUU m6b Disrupted 0.005000 -0.022000 0.170000
hsa-miR-3924 tgtgATACATAgccccagc
0 AUAUGUAU m7b Created no TS 0.152000 -0.020000
hsa-miR-4489 tgtgatacaTAGCCCCAgc
9
UGGGGCUA m8a (m7a->m8a) -0.111000 -0.260000 -0.220000
hsa-miR-4492 tgtgatacaCAGCCCCagc
1
GGGGCUGG m7a (m7a->m6a) -0.075000 -0.075000 No effect
hsa-miR-4675 tgtgatacACAGCCCCagc
2
GGGGCUGU m8a Disrupted -0.078000 no TS 0.020000
hsa-miR-4741 tgtgatacACAGCCCcagc
2
CGGGCUGU m7b Disrupted -0.078000 no TS 0.040000
hsa-miR-762 tgtgatacaCAGCCCCagc
1
GGGGCUGG m7a (m7a->m6a) -0.075000 -0.075000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr9:g.123380878C>A COSN5242180 SS6003323 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-137 tgtttctAGCAATAtacac
12
UUAUUGCU m7b Disrupted -0.105000 no TS 14.400000
hsa-miR-4777-5p tgttTCTAGAAatatacac
0 UUCUAGAU m7a Created no TS -0.048000 -0.740000
hsa-miR-518d-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -6.120000
hsa-miR-518e-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-518f-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -6.070000
hsa-miR-519a-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-519b-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-519c-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-520c-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -6.120000
hsa-miR-522-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-523-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-526a tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -6.120000
hsa-miR-137 tgtttctAGCAATAtacac
12
UUAUUGCU m7b Disrupted -0.105000 no TS 14.400000
hsa-miR-4777-5p tgttTCTAGAAatatacac
0 UUCUAGAU m7a Created no TS -0.048000 -0.740000
hsa-miR-518d-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -6.120000
hsa-miR-518e-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-518f-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -6.070000
hsa-miR-519a-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-519b-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-519c-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-520c-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -6.120000
hsa-miR-522-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-523-5p tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -8.890000
hsa-miR-526a tgttTCTAGAaatatacac
0 CUCUAGAG m6b Created no TS -0.046000 -6.120000

Mutation Mutation ID Sample Name Cancer Type
chr9:g.123381401G>C COSN15103123 SM-4B296 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1268a atgcaccgACGCCCGaggg
2
CGGGCGUG m7a Created -0.380000 -0.380000 No effect
hsa-miR-1268b atgcaccgACGCCCGaggg
2
CGGGCGUG m7a Created -0.380000 -0.380000 No effect
hsa-miR-3181 atgcaccgaGGCCCGAggg
2
AUCGGGCC m7b (m7b->m6b) -0.628000 -0.337000 -1.570000
hsa-miR-4750 atgcaccgaCGCCCGAGgg
0 CUCGGGCG m8a (m7a->m8a) no TS -0.300000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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