SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_133506
Gene Symbol: DCN
Description: Homo sapiens decorin (DCN), transcript variant A1, mRNA.
Gene Location: chr12(-):91539034-91572329
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Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr12:g.91145300C>G COSN5331426 RK298_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-10a-3p ctgatgtttGAATTTaccc
0 CAAAUUCG m6b Created no TS -0.022000 -6.480000
hsa-miR-4760-3p ctgatgttTGAATTTaccc
0 AAAUUCAU m7a Created NA NA -2.730000
hsa-miR-494 ctgATGTTTCAatttaccc
2
UGAAACAU m8a Disrupted -0.196000 no TS 4.470000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.91145332C>T COSN5331427 RK125_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1277-5p caaagcATATATTTcctga
0 AAAUAUAU m8a Created no TS 0.045000 -0.060000
hsa-miR-5093 caaagcataCATTTCCTga
0 AGGAAAUG m8a (m8a->m7a) -0.291000 -0.125000 1.590000
hsa-miR-675-3p caaaGCATACAtttcctga
0 CUGUAUGC m7b Disrupted -0.260000 no TS 0.500000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.91145627G>A COSN9084881 8051715 [pancreas][NS][carcinoid-endocrine_tumour][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3923 atcatTACTAGTaaagcct
0 AACUAGUA m7b Created no TS -0.358000 -2.370000
hsa-miR-628-3p atcaTTACTAGtaaagcct
1
UCUAGUAA m7b Created -0.110000 -0.275000 -2.320000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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