SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_000499 |
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Gene Symbol: | CYP1A1 |
Description: | Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), mRNA. |
Gene Location: | chr15(-):75011882-75017877 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr15:g.74719774G>- | ICGC_ssm_v2_93925 | HX13T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4640-3p |
gagggGGGGGTatttcaat |
0 | CACCCCCU | m6b | Disrupted | -0.220000 | -0.230000 |
0.020000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr15:g.74720282C>A | COSN1180086 | HCC63T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4724-3p |
cagagacaaAAGGTAaaac |
0 | GUACCUUC | m6b | Created | no TS | -0.074000 |
-6.640000 |
hsa-miR-4724-3p |
cagagacaaAAGGTAaaac |
0 | GUACCUUC | m6b | Created | no TS | -0.074 |
-6.64 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
74719773 | rs200937928 | - | - |
hsa-miR-4640-3p hsa-miR-6798-3p |
0 |
gGGGGGTAtttca gGGGGGTAtttca |
Unknown Unknown |
N N |
-0.001 0.022 |
G | |||||||||
74719775 | rs28399432 | G | G |
hsa-miR-4640-3p hsa-miR-6798-3p |
0 |
gggGGGGGTAttt gggGGGGGTAttt |
Disrupted Disrupted |
N N |
-0.22 -0.246 |
74719776 | rs17861085 | T | G |
hsa-miR-6798-3p |
0 |
agggGGGGGTAtt |
Created |
N |
-0.246 |
T |
hsa-miR-4640-3p |
0 |
AGGGGGTggtatt |
Disrupted |
N |
-0.01 |