SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_003467
Gene Symbol: CXCR4
Description: Homo sapiens chemokine (C-X-C motif) receptor 4 (CXCR4), transcript variant 1, mRNA.
Gene Location: chr2(-):136871918-136875725
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr2:g.136114570A>G COSN8607517 J30_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3180-5p cgtaaagCTGGAAatgatc
 0 CUUCCAGA m6b Created no TS -0.092000 -6.060000
hsa-miR-4267 cgtaaAGCTGGAaatgatc
 0 UCCAGCUC m7a Created no TS -0.153000 -0.220000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.136114643C>A COSN4796333 tumor_4194218 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][Burkitt_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3120-3p tcttagTTGCTGTatgtct
 7
 CACAGCAA m7b Disrupted -0.567000 -0.315000 5.870000
hsa-miR-499a-3p tcttagtTGATGTatgtct
 0 AACAUCAC m6b Created no TS -0.066000 -4.710000
hsa-miR-499b-3p tcttagtTGATGTatgtct
 0 AACAUCAC m6b Created no TS -0.066000 -4.300000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.136114781T>C COSN8268699 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-338-5p ccaATATTGTacagttttt
 1
 AACAAUAU m7b (m7b->m6c) -0.196000 no TS 2.170000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.136114819T>A COSN8607518 1287_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-200a-5p tttttTAAGATacacattt
 0 CAUCUUAC m6b Created no TS -0.106000 No effect
hsa-miR-200b-5p tttttTAAGATacacattt
 0 CAUCUUAC m6b Created no TS -0.099000 0.430000
hsa-miR-223-5p ttttttaagATACACattt
 0 CGUGUAUU m6b Created no TS -0.155000 -6.560000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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