SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001178134
Gene Symbol: CXCL12
Description: Homo sapiens chemokine (C-X-C motif) ligand 12 (CXCL12), transcript variant 2, mRNA.
Gene Location: chr10(-):44872509-44880545
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr10:g.44377104T>A COSN9209007 AOCS-058-1-5 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5692a gggaatTTATTTacctgaa
 15
 CAAAUAAU m6b Disrupted 0.058000 no TS 0.310000


Mutation Mutation ID Sample Name Cancer Type
chr10:g.44377355A>G COSN1489835 RK015_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr10:g.44377589G>A COSN6971134 8031121 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-129-5p atcagaaGCAAAAAaatca
 0 CUUUUUGC m7b Created no TS -0.203000 -0.040000
hsa-miR-3977 atcaGAAGCAaaaaaatca
 0 GUGCUUCA m6b Created no TS -0.134000 -0.350000
hsa-miR-4790-5p atcagAAGCGAaaaaatca
 1
 AUCGCUUU m6b Disrupted -0.229000 no TS 14.080000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.44377710G>T COSN1119220 HCC29T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3607-3p gtcTTTACAGaatcaaatg
 2
 ACUGUAAA m7b (m7b->m6c) -0.233000 no TS 3.680000
hsa-miR-3686 gtctTTACAGAatcaaatg
 2
 AUCUGUAA m7b Disrupted -0.279000 no TS 3.060000
hsa-miR-379-3p gtctTTACATAatcaaatg
 0 UAUGUAAC m7a Created no TS -0.052000 -0.360000
hsa-miR-380-3p gtctTTACATAatcaaatg
 0 UAUGUAAU m7a Created no TS -0.047000 -0.300000
hsa-miR-3924 gtcttTACATAatcaaatg
 0 AUAUGUAU m6b Created no TS -0.068000 -0.410000
hsa-miR-411-3p gtctTTACATAatcaaatg
 0 UAUGUAAC m7a Created no TS -0.052000 -0.400000
hsa-miR-4495 gtcTTTACATaatcaaatg
 0 AAUGUAAA m7b (m6c->m7b) no TS -0.193000 -4.420000
hsa-miR-4778-5p gtctttACAGAATcaaatg
 2
 AAUUCUGU m7b Disrupted -0.182000 no TS 6.330000
hsa-miR-3607-3p gtcTTTACAGaatcaaatg
 2
 ACUGUAAA m7b (m7b->m6c) -0.233000 no TS 3.680000
hsa-miR-3686 gtctTTACAGAatcaaatg
 2
 AUCUGUAA m7b Disrupted -0.279000 no TS 3.060000
hsa-miR-379-3p gtctTTACATAatcaaatg
 0 UAUGUAAC m7a Created no TS -0.052000 -0.360000
hsa-miR-380-3p gtctTTACATAatcaaatg
 0 UAUGUAAU m7a Created no TS -0.047000 -0.300000
hsa-miR-3924 gtcttTACATAatcaaatg
 0 AUAUGUAU m6b Created no TS -0.068000 -0.410000
hsa-miR-411-3p gtctTTACATAatcaaatg
 0 UAUGUAAC m7a Created no TS -0.052000 -0.400000
hsa-miR-4495 gtcTTTACATaatcaaatg
 0 AAUGUAAA m7b (m6c->m7b) no TS -0.193000 -4.420000
hsa-miR-4778-5p gtctttACAGAATcaaatg
 2
 AAUUCUGU m7b Disrupted -0.182000 no TS 6.330000
hsa-miR-3607-3p gtcTTTACAGaatcaaatg
 2
 ACUGUAAA m7b (m7b->m6c) -0.233000 no TS 3.680000
hsa-miR-3686 gtctTTACAGAatcaaatg
 2
 AUCUGUAA m7b Disrupted -0.279000 no TS 3.060000
hsa-miR-379-3p gtctTTACATAatcaaatg
 0 UAUGUAAC m7a Created no TS -0.052000 -0.360000
hsa-miR-380-3p gtctTTACATAatcaaatg
 0 UAUGUAAU m7a Created no TS -0.047000 -0.300000
hsa-miR-3924 gtcttTACATAatcaaatg
 0 AUAUGUAU m6b Created no TS -0.068000 -0.410000
hsa-miR-411-3p gtctTTACATAatcaaatg
 0 UAUGUAAC m7a Created no TS -0.052000 -0.400000
hsa-miR-4495 gtcTTTACATaatcaaatg
 0 AAUGUAAA m7b (m6c->m7b) no TS -0.193000 -4.420000
hsa-miR-4778-5p gtctttACAGAATcaaatg
 2
 AAUUCUGU m7b Disrupted -0.182000 no TS 6.330000
hsa-miR-3607-3p gtcTTTACAGaatcaaatg
 0 ACUGUAAA m7b (m7b->m6c) -0.233 no TS 3.68
hsa-miR-3686 gtctTTACAGAatcaaatg
 0 AUCUGUAA m7b Disrupted -0.279 no TS 3.06
hsa-miR-379-3p gtctTTACATAatcaaatg
 0 UAUGUAAC m7a Created no TS -0.052 -0.36
hsa-miR-380-3p gtctTTACATAatcaaatg
 0 UAUGUAAU m7a Created no TS -0.047 -0.3
hsa-miR-3924 gtcttTACATAatcaaatg
 0 AUAUGUAU m6b Created no TS -0.068 -0.41
hsa-miR-411-3p gtctTTACATAatcaaatg
 0 UAUGUAAC m7a Created no TS -0.052 -0.4
hsa-miR-4495 gtcTTTACATaatcaaatg
 0 AAUGUAAA m7b (m6c->m7b) no TS -0.193 -4.42
hsa-miR-4778-5p gtctttACAGAATcaaatg
 0 AAUUCUGU m7b Disrupted -0.182 no TS 6.33

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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