SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001171172
Gene Symbol: CX3CR1
Description: Homo sapiens chemokine (C-X3-C motif) receptor 1 (CX3CR1), transcript variant 2, mRNA.
Gene Location: chr3(-):39304984-39321930
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr3:g.39263823A>C COSN7608392 8067211 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-618 catgttTAGAGTTgcaatc
 4
 AAACUCUA m7b Disrupted -0.124000 no TS 5.180000
hsa-miR-891a catgtttagCGTTGCAatc
 0 UGCAACGA m7a (m6a->m7a) no TS -0.235000 -6.920000
hsa-miR-891b catgtttagAGTTGCAatc
 4
 UGCAACUU m7a (m7a->m6a) -0.139000 no TS 5.410000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.39264138C>A COSN7608393 8031681 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-122-5p gagCACTCCAaagtctaca
 0 UGGAGUGU m7a (m6b->m7a) no TS -0.094000 -0.030000
hsa-miR-30b-3p gagcaCTCCCAagtctaca
 5
 CUGGGAGG m6b Disrupted -0.129000 -0.092000 0.130000
hsa-miR-30c-1-3p gagcaCTCCCAagtctaca
 2
 CUGGGAGA m6b Disrupted -0.045000 no TS No effect
hsa-miR-30c-2-3p gagcaCTCCCAagtctaca
 2
 CUGGGAGA m6b Disrupted -0.048000 no TS No effect
hsa-miR-3198 gagcACTCCAaagtctaca
 0 GUGGAGUC m6b Created -0.086000 -0.150000 No effect
hsa-miR-3689a-3p gagcaCTCCCAagtctaca
 5
 CUGGGAGG m6b Disrupted -0.163000 -0.129000 0.010000
hsa-miR-3689b-3p gagcaCTCCCAagtctaca
 5
 CUGGGAGG m6b Disrupted -0.172000 -0.138000 0.040000
hsa-miR-3689c gagcaCTCCCAagtctaca
 5
 CUGGGAGG m6b Disrupted -0.172000 -0.138000 0.040000
hsa-miR-4309 gagcACTCCAaagtctaca
 0 CUGGAGUC m6b Created -0.030000 -0.087000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.39264260C>G COSN5535850 RK124_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4519 cacctggCACTGCTGtgct
 2
 CAGCAGUG m8a Disrupted -0.042000 no TS 1.020000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.39264883T>G COSN15246270 LP6007420-DNA_A01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1261 aaggtgctgTTATCCATgg
 2
 AUGGAUAA m8a (m8a->m7a) 0.001000 no TS No effect
hsa-miR-634 aaggTGCTGGTatccatgg
 0 AACCAGCA m7b Created no TS -0.234000 -4.550000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.39265006G>A COSN6574322 ICGC_MB61 [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-379-3p actTTACATAacacagctt
 0 UAUGUAAC m7a (m6b->m7a) no TS 0.014000 -2.270000
hsa-miR-380-3p actTTACATAacacagctt
 0 UAUGUAAU m7a (m6b->m7a) no TS 0.019000 -2.290000
hsa-miR-3924 acttTACATAacacagctt
 0 AUAUGUAU m6b Created -0.240000 -0.229000 -2.170000
hsa-miR-411-3p actTTACATAacacagctt
 0 UAUGUAAC m7a (m6b->m7a) no TS 0.014000 -2.280000
hsa-miR-592 actttacaTGACACAgctt
 2
 UUGUGUCA m7b Disrupted -0.124000 no TS 0.360000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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