| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_001037631 |
|---|---|
| Gene Symbol: | CTLA4 |
| Description: | Homo sapiens cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 2, mRNA. |
| Gene Location: | chr2(+):204732510-204738683 |
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| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.203872836C>T | cosmic_v64_1675361 | Melanoma | ||||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-4517 |
gaagagagtTCATATTTca |
0 | AAAUAUGA | m8a | (m7b->m8a) | no TS | -0.132 |
-0.35 |
| hsa-miR-4680-5p |
gaagAGAGTTCatatttca |
0 | AGAACUCU | m7b | Created | no TS | -0.379 |
-9.99 |
| hsa-miR-5583-3p |
gaagagagtCCATATTtca |
0 | GAAUAUGG | m7b | (m7b->m6c) | -0.151 | no TS |
0.62 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.203873372A>G | COSN14852701 | LP6005334-DNA_C03 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1185-1-3p |
tatatataTGTATATatat |
18 |
AUAUACAG | m7a | Created | -0.073000 | -0.073000 | No effect |
| hsa-miR-1185-2-3p |
tatatataTGTATATatat |
18 |
AUAUACAG | m7a | Created | -0.073000 | -0.073000 | No effect |
| hsa-miR-5011-5p |
tatatataTATATATAtat |
0 | UAUAUAUA | m8a | Disrupted | -2.467000 | -2.027000 |
0.320000 |
| hsa-miR-5580-3p |
tatatATATGTatatatat |
0 | CACAUAUG | m6b | Created | no TS | -0.042000 |
0.010000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.203873382A>T | COSN6933208 | 8014741 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1277-5p |
tatatATATATTTtaattt |
0 | AAAUAUAU | m8a | Disrupted | -0.150000 | -0.155000 |
-0.040000 |
| hsa-miR-5011-5p |
taTATATATAttttaattt |
0 | UAUAUAUA | m8a | (m8a->m7a) | -2.467000 | -2.387000 |
-0.180000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.203873791C>A | COSN8608448 | 3402_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3658 |
caaTTCTTAAAaacatgtg |
1 |
UUUAAGAA | m8a | Created | -0.122000 | -0.275000 |
-0.450000 |
| hsa-miR-4307 |
caattcttaAAAACATgtg |
0 | AAUGUUUU | m7b | (m6c->m7b) | no TS | -0.044000 |
-3.140000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.203873872T>G | COSN8608449 | 1287_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-4519 |
aattaaCACTGCTtgtgtt |
3 |
CAGCAGUG | m7b | Disrupted | -0.255000 | no TS |
1.040000 |