SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001130518
Gene Symbol: CSGALNACT1
Description: Homo sapiens chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1), transcript variant 1, mRNA.
Gene Location: chr8(-):19261671-19460056
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr8:g.19404210G>T COSN8576018 tumor_4108101 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5197-5p acagGCCATTaatggaagg
 0 CAAUGGCA m6b Created no TS -0.153000 0.900000
hsa-miR-885-5p acaggccatTAATGGAagg
 0 UCCAUUAC m7a (m6a->m7a) no TS -0.102000 -0.110000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.19404590T>A COSN2268883 RK015_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1246 atcAATCCATctgccagaa
 3
 AAUGGAUU m7b (m7b->m6c) -0.073000 no TS 0.210000
hsa-miR-3134 atcaATCCATCtgccagaa
 4
 UGAUGGAU m7b Disrupted -0.159000 no TS 3.610000
hsa-miR-34c-5p atcaatccaACTGCCagaa
 0 AGGCAGUG m6b Created no TS -0.125000 -1.300000
hsa-miR-449b-5p atcaatccaACTGCCagaa
 0 AGGCAGUG m6b Created no TS -0.131000 -2.530000
hsa-miR-5004-3p atcAATCCAActgccagaa
 0 CUUGGAUU m7b (m6c->m7b) no TS -0.062000 -0.020000
hsa-miR-548au-3p atcaatccAACTGCCAgaa
 0 UGGCAGUU m8a Created no TS -0.309000 -0.050000
hsa-miR-1246 atcAATCCATctgccagaa
 3
 AAUGGAUU m7b (m7b->m6c) -0.073000 no TS 0.210000
hsa-miR-3134 atcaATCCATCtgccagaa
 4
 UGAUGGAU m7b Disrupted -0.159000 no TS 3.610000
hsa-miR-34c-5p atcaatccaACTGCCagaa
 0 AGGCAGUG m6b Created no TS -0.125000 -1.300000
hsa-miR-449b-5p atcaatccaACTGCCagaa
 0 AGGCAGUG m6b Created no TS -0.131000 -2.530000
hsa-miR-5004-3p atcAATCCAActgccagaa
 0 CUUGGAUU m7b (m6c->m7b) no TS -0.062000 -0.020000
hsa-miR-548au-3p atcaatccAACTGCCAgaa
 0 UGGCAGUU m8a Created no TS -0.309000 -0.050000
hsa-miR-1246 atcAATCCATctgccagaa
 0 AAUGGAUU m7b (m7b->m6c) -0.073 no TS 0.21
hsa-miR-3134 atcaATCCATCtgccagaa
 0 UGAUGGAU m7b Disrupted -0.159 no TS 3.61
hsa-miR-34c-5p atcaatccaACTGCCagaa
 0 AGGCAGUG m6b Created no TS -0.125 -1.3
hsa-miR-449b-5p atcaatccaACTGCCagaa
 0 AGGCAGUG m6b Created no TS -0.131 -2.53
hsa-miR-5004-3p atcAATCCAActgccagaa
 0 CUUGGAUU m7b (m6c->m7b) no TS -0.062 -0.02
hsa-miR-548au-3p atcaatccAACTGCCAgaa
 0 UGGCAGUU m8a Created no TS -0.309 -0.05

Mutation Mutation ID Sample Name Cancer Type
chr8:g.19404607T>A COSN6518286 HX35T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1277-5p tatATATATTgtgaaagat
 2
 AAAUAUAU m7b (m7b->m6c) -0.105000 no TS -0.480000
hsa-miR-338-5p tatatATATTGTgaaagat
 0 AACAAUAU m7b Disrupted -0.067000 no TS No effect
hsa-miR-5011-5p taTATATATAgtgaaagat
 2
 UAUAUAUA m8a (m7b->m8a) -0.285000 -0.290000 0.240000
hsa-miR-513b tatatataTTGTGAAagat
 2
 UUCACAAG m7a Disrupted -0.253000 -0.181000 0.030000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.19404905A>C COSN1362315 HX10T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4742-3p ctAATACAGAcgtacagat
 7
 UCUGUAUU m8a (m8a->m7b) -0.273000 -0.219000 0.260000
hsa-miR-4999-5p ctaATACAGCcgtacagat
 0 UGCUGUAU m7b (m6c->m7b) no TS -0.107000 -0.010000
hsa-miR-4742-3p ctAATACAGAcgtacagat
 0 UCUGUAUU m8a (m8a->m7b) -0.273 -0.219 0.26
hsa-miR-4999-5p ctaATACAGCcgtacagat
 0 UGCUGUAU m7b (m6c->m7b) no TS -0.107 -0.01

Mutation Mutation ID Sample Name Cancer Type
chr8:g.19405492C>T COSN524459 TCGA-A8-A083-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-223-5p tgtttacAATACACtgaga
 0 CGUGUAUU m7b Created no TS -0.083000 0.010000
hsa-miR-4302 tgtttacaaCACACTGaga
 0 CCAGUGUG m7b (m7b->m6b) -0.288000 -0.084000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr8:g.19405744T>G COSN1084577 TCGA-AP-A056-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
19404595 rs7005528 A A hsa-miR-1246
hsa-miR-3134
hsa-miR-7641
3
4
2
 agatcAATCCATc
agatcaATCCATC
AGATCAAtccatc
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.073
-0.159
-0.08
G hsa-miR-1269a
hsa-miR-1269b
hsa-miR-1288-3p
hsa-miR-4515
hsa-miR-4740-5p
2
2
2
2
2
 agatCAGTCCAtc
agatCAGTCCAtc
agatCAGTCCAtc
agatCAGTCCAtc
agaTCAGTCCAtc
 Created
Created
Created
Created
Created
N
N
N
N
N
 -0.21
-0.21
-0.161
-0.142
-0.376
19404610 rs71945232 - - hsa-miR-1277-5p
hsa-miR-338-5p
hsa-miR-5011-5p
2
0
2
 atatatATATATTgtgaaa
atatatatATATTGTgaaa
ataTATATATAttgtgaaa
 Unknown
Unknown
Unknown
N
N
N
 -0.105
-0.067
-0.072
ATAT hsa-miR-190a-3p
hsa-miR-5692b
hsa-miR-5692c
hsa-miR-656-3p
3
2
2
2
 atATATATAAtattattgtgaaa
atatatataATATTATtgtgaaa
atatatataATATTATtgtgaaa
atatatATAATATtattgtgaaa
 Unknown
Unknown
Unknown
Unknown
N
N
N
N
 0.039
-0.055
-0.055
-0.047
19404623 rs200657065 - - hsa-miR-190a-3p
hsa-miR-5011-5p
1
1
 gagaaaaaaATATATAtat
gagaaaaaaATATATAtat
 Unknown
Unknown
N
N
 0.263
0.221
ATAT
19404624 rs57082500 A
T hsa-miR-190a-3p
hsa-miR-5011-5p
0 gaaaaATATATAt
gaaaaaTATATAT
 Created
Created
N
N
 -0.121
-0.097
19404910 rs138952542 T T hsa-miR-4742-3p
1
 tactAATACAGAc
 Disrupted
N
 -0.047
C hsa-miR-3152-3p
1
 taCTAACACAgac
 Created
N
 -0.153
19405492 rs3802330 C C hsa-miR-3613-5p
hsa-miR-4302
3
0
 tTACAACAcactg
ttacaaCACACTG
 Disrupted
Disrupted
N
N
 -0.059
-0.204
T hsa-miR-223-5p
0 ttacAATACACtg
 Created
N
 -0.083

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