SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_004375
Gene Symbol: COX11
Description: Homo sapiens COX11 cytochrome c oxidase assembly homolog (yeast) (COX11), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA.
Gene Location: chr17(-):53038566-53046064
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr17:g.54961532T>A COSN1198723 HCC82T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1245b-5p aggAAGGCCTgtgaaacat
 5
 UAGGCCUU m7b (m7b->m6c) -0.171000 no TS 0.050000
hsa-miR-181b-3p aggaaggcCAGTGAaacat
 0 CUCACUGA m6b Created no TS -0.073000 -0.070000
hsa-miR-193a-3p aggaaGGCCAGTgaaacat
 1
 AACUGGCC m7b Created -0.625000 -0.885000 -0.010000
hsa-miR-193b-3p aggaaGGCCAGTgaaacat
 1
 AACUGGCC m7b Created -0.625000 -0.885000 -4.160000
hsa-miR-27a-3p aggaaggcCTGTGAAacat
 6
 UUCACAGU m7a Disrupted -0.067000 no TS 5.330000
hsa-miR-27b-3p aggaaggcCTGTGAAacat
 6
 UUCACAGU m7a Disrupted -0.067000 no TS 5.330000
hsa-miR-3142 aggAAGGCCTgtgaaacat
 5
 AAGGCCUU m7b (m7b->m6c) -0.171000 no TS 2.780000
hsa-miR-3176 aggaAGGCCAGTgaaacat
 0 ACUGGCCU m8a Created -0.436000 -0.706000 -0.010000
hsa-miR-3922-3p aggaAGGCCAGtgaaacat
 0 UCUGGCCU m7b Created -0.499000 -0.722000 No effect
hsa-miR-4420 aggaaggcCAGTGAaacat
 0 GUCACUGA m6b Created no TS -0.076000 No effect
hsa-miR-4438 aggaagGCCTGTGaaacat
 0 CACAGGCU m7a Disrupted NA NA 5.230000
hsa-miR-4650-5p aggaAGGCCTGtgaaacat
 5
 UCAGGCCU m7b Disrupted -0.273000 no TS 8.840000
hsa-miR-513a-5p aggaaggCCTGTGAAacat
 5
 UUCACAGG m8a Disrupted -0.263000 no TS 1.860000
hsa-miR-892b aggaagGCCAGTGaaacat
 2
 CACUGGCU m7a Created -0.262000 -0.262000 -0.020000
hsa-miR-1245b-5p aggAAGGCCTgtgaaacat
 5
 UAGGCCUU m7b (m7b->m6c) -0.171000 no TS 0.050000
hsa-miR-181b-3p aggaaggcCAGTGAaacat
 0 CUCACUGA m6b Created no TS -0.073000 -0.070000
hsa-miR-193a-3p aggaaGGCCAGTgaaacat
 1
 AACUGGCC m7b Created -0.625000 -0.885000 -0.010000
hsa-miR-193b-3p aggaaGGCCAGTgaaacat
 1
 AACUGGCC m7b Created -0.625000 -0.885000 -4.160000
hsa-miR-27a-3p aggaaggcCTGTGAAacat
 6
 UUCACAGU m7a Disrupted -0.067000 no TS 5.330000
hsa-miR-27b-3p aggaaggcCTGTGAAacat
 6
 UUCACAGU m7a Disrupted -0.067000 no TS 5.330000
hsa-miR-3142 aggAAGGCCTgtgaaacat
 5
 AAGGCCUU m7b (m7b->m6c) -0.171000 no TS 2.780000
hsa-miR-3176 aggaAGGCCAGTgaaacat
 0 ACUGGCCU m8a Created -0.436000 -0.706000 -0.010000
hsa-miR-3922-3p aggaAGGCCAGtgaaacat
 0 UCUGGCCU m7b Created -0.499000 -0.722000 No effect
hsa-miR-4420 aggaaggcCAGTGAaacat
 0 GUCACUGA m6b Created no TS -0.076000 No effect
hsa-miR-4438 aggaagGCCTGTGaaacat
 0 CACAGGCU m7a Disrupted NA NA 5.230000
hsa-miR-4650-5p aggaAGGCCTGtgaaacat
 5
 UCAGGCCU m7b Disrupted -0.273000 no TS 8.840000
hsa-miR-513a-5p aggaaggCCTGTGAAacat
 5
 UUCACAGG m8a Disrupted -0.263000 no TS 1.860000
hsa-miR-892b aggaagGCCAGTGaaacat
 2
 CACUGGCU m7a Created -0.262000 -0.262000 -0.020000
hsa-miR-1245b-5p aggAAGGCCTgtgaaacat
 0 UAGGCCUU m7b (m7b->m6c) -0.171 no TS 0.05
hsa-miR-181b-3p aggaaggcCAGTGAaacat
 0 CUCACUGA m6b Created no TS -0.073 -0.07
hsa-miR-193a-3p aggaaGGCCAGTgaaacat
 0 AACUGGCC m7b Created -0.625 -0.885 -0.01
hsa-miR-193b-3p aggaaGGCCAGTgaaacat
 0 AACUGGCC m7b Created -0.625 -0.885 -4.16
hsa-miR-27a-3p aggaaggcCTGTGAAacat
 0 UUCACAGU m7a Disrupted -0.067 no TS 5.33
hsa-miR-27b-3p aggaaggcCTGTGAAacat
 0 UUCACAGU m7a Disrupted -0.067 no TS 5.33
hsa-miR-3142 aggAAGGCCTgtgaaacat
 0 AAGGCCUU m7b (m7b->m6c) -0.171 no TS 2.78
hsa-miR-3176 aggaAGGCCAGTgaaacat
 0 ACUGGCCU m8a Created -0.436 -0.706 -0.01
hsa-miR-3922-3p aggaAGGCCAGtgaaacat
 0 UCUGGCCU m7b Created -0.499 -0.722 No effect
hsa-miR-4420 aggaaggcCAGTGAaacat
 0 GUCACUGA m6b Created no TS -0.076 No effect
hsa-miR-4438 aggaagGCCTGTGaaacat
 0 CACAGGCU m7a Disrupted NA NA 5.23
hsa-miR-4650-5p aggaAGGCCTGtgaaacat
 0 UCAGGCCU m7b Disrupted -0.273 no TS 8.84
hsa-miR-513a-5p aggaaggCCTGTGAAacat
 0 UUCACAGG m8a Disrupted -0.263 no TS 1.86
hsa-miR-892b aggaagGCCAGTGaaacat
 0 CACUGGCU m7a Created -0.262 -0.262 -0.02

Mutation Mutation ID Sample Name Cancer Type
chr17:g.54961962A>C COSN8839814 AOCS-161-1-9 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-200b-3p aaaaaaAGTATTAaattgt
 2
 UAAUACUG m7a Disrupted -0.249000 -0.228000 No effect
hsa-miR-200c-3p aaaaaaAGTATTAaattgt
 2
 UAAUACUG m7a Disrupted -0.249000 -0.228000 0.030000
hsa-miR-208a aaaaaaaGTCTTAaattgt
 0 AUAAGACG m6b Created no TS -0.086000 -2.350000
hsa-miR-208b aaaaaaaGTCTTAaattgt
 0 AUAAGACG m6b Created no TS -0.090000 -17.180000
hsa-miR-374c-5p aaaaaaaGTATTAaattgt
 0 AUAAUACA m6b Disrupted -0.012000 no TS 1.000000
hsa-miR-429 aaaaaaAGTATTAaattgt
 2
 UAAUACUG m7a Disrupted -0.221000 -0.200000 No effect
hsa-miR-4432 aaaaaaAGTCTTaaattgt
 0 AAAGACUC m6b Created no TS -0.069000 No effect
hsa-miR-499a-5p aaaaaaAGTCTTAAattgt
 0 UUAAGACU m8a Created no TS -0.211000 -1.320000
hsa-miR-655 aaaaaaaGTATTAaattgt
 0 AUAAUACA m6b Disrupted -0.019000 no TS 1.707000

Mutation Mutation ID Sample Name Cancer Type
chr17:g.54962487A>C COSN6107147 RK212_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2054 atacTATTACAataagccg
 0 CUGUAAUA m7b Created 0.030000 -0.121000 -2.455000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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