| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_001135161 |
|---|---|
| Gene Symbol: | COMT |
| Description: | Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA. |
| Gene Location: | chr22(+):19938459-19957498 |
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| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr22:g.19968976A>G | COSN1895000 | RK084_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3145-3p |
tatactAATATCatgtttt |
2 |
AGAUAUUU | m6b | Disrupted | -0.048000 | no TS |
5.650000 |
| hsa-miR-3145-3p |
tatactAATATCatgtttt |
2 |
AGAUAUUU | m6b | Disrupted | -0.048000 | no TS |
5.650000 |
| hsa-miR-3145-3p |
tatactAATATCatgtttt |
2 |
AGAUAUUU | m6b | Disrupted | -0.048 | no TS |
5.65 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr22:g.19969578T>A | COSN5988978 | RK308_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-204-3p |
agggcccagTTCCCAGgcc |
1 |
GCUGGGAA | m7b | (m7b->m6c) | -0.002000 | no TS |
0.080000 |
| hsa-miR-4471 |
agggcccAGTTCCCAggcc |
1 |
UGGGAACU | m8a | Disrupted | -0.170000 | no TS |
2.460000 |
| hsa-miR-450b-3p |
agggcccaGATCCCAggcc |
0 | UUGGGAUC | m7b | Created | no TS | -0.082000 |
-0.010000 |
| hsa-miR-4646-5p |
agggcccagTTCCCAGgcc |
1 |
ACUGGGAA | m7b | (m7b->m6c) | -0.011000 | no TS |
0.040000 |
| hsa-miR-638 |
agggcccaGATCCCaggcc |
0 | AGGGAUCG | m6b | Created | no TS | -0.099000 |
-2.200000 |
| hsa-miR-769-3p |
agggcccaGATCCCAGgcc |
0 | CUGGGAUC | m8a | Created | no TS | -0.092000 |
-4.060000 |