| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_000093 |
|---|---|
| Gene Symbol: | COL5A1 |
| Description: | Homo sapiens collagen, type V, alpha 1 (COL5A1), mRNA. |
| Gene Location: | chr9(+):137533651-137736688 |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.134842318G>A | COSN4894239 | PCSI_0010_Pa_X | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-378g |
gccgAGCCCAGgctcccga |
5 |
ACUGGGCU | m7b | Created | -0.090000 | 0.000000 | No effect | |
| hsa-miR-3940-3p |
gccgagcCCGGGCTcccga |
2 |
CAGCCCGG | m7b | Disrupted | 0.000000 | no TS | No effect | |
| hsa-miR-4674 |
gccGAGCCCAGgctcccga |
5 |
CUGGGCUC | m8a | Created | -0.114000 | -0.228000 | No effect | |
| hsa-miR-661 |
gccgagCCCAGGCtcccga |
0 | UGCCUGGG | m7b | Created | no TS | 0.000000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.134842358G>A | COSN8296499 | ASHPC_0001_Pa_P_2 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.134842975C>T | COSN6381778 | RK308_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-660-5p |
cagAATGGGTgaggcatgg |
0 | UACCCAUU | m7b | (m6b->m7b) | no TS | -0.033000 |
-2.850000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.134843036C>A | COSN14781834 | CHC205T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1908 |
ccccacCCCCGCCctggcc |
2 |
CGGCGGGG | m7b | Disrupted | -0.178000 | no TS |
0.210000 |
|
| hsa-miR-3141 |
ccccacccCCGCCCTggcc |
2 |
GAGGGCGG | m7b | Disrupted | -0.176000 | no TS |
1.410000 |
|
| hsa-miR-4446-3p |
ccccacccCAGCCCTGgcc |
0 | CAGGGCUG | m8a | Created | no TS | -0.056000 |
-3.650000 |
|
| hsa-miR-4492 |
ccccaccCCAGCCCtggcc |
0 | GGGGCUGG | m7b | Created | -0.237000 | -0.291000 |
-0.050000 |
|
| hsa-miR-4498 |
ccccaccCCAGCCCtggcc |
0 | UGGGCUGG | m7b | Created | -0.264000 | -0.355000 |
-2.450000 |
|
| hsa-miR-4505 |
ccccacCCCAGCCctggcc |
0 | AGGCUGGG | m7b | Created | -0.120000 | -0.230000 |
-9.130000 |
|
| hsa-miR-4731-5p |
ccccaCCCCAGCcctggcc |
2 |
UGCUGGGG | m7b | Created | -0.401000 | -0.499000 |
-0.060000 |
|
| hsa-miR-4787-5p |
ccccACCCCCGCcctggcc |
0 | GCGGGGGU | m8a | Disrupted | -0.335000 | -0.204000 |
4.040000 |
|
| hsa-miR-5001-5p |
ccccaccCCAGCCCTggcc |
0 | AGGGCUGG | m8a | Created | -0.227000 | -0.309000 |
-1.190000 |
|
| hsa-miR-663a |
ccccacCCCCGCCctggcc |
2 |
AGGCGGGG | m7b | Disrupted | -0.188000 | no TS |
0.940000 |
|
| hsa-miR-762 |
ccccaccCCAGCCCtggcc |
0 | GGGGCUGG | m7b | Created | -0.237000 | -0.366000 |
-0.180000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.134843284G>A | COSN8520228 | 742_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-150-5p |
gagcctgaTGGGAGAatgt |
7 |
UCUCCCAA | m7a | Disrupted | -0.015000 | no TS | No effect | |
| hsa-miR-2116-3p |
gagcctgATGGGAGaatgt |
7 |
CCUCCCAU | m7b | Disrupted | -0.072000 | no TS |
0.160000 |
|
| hsa-miR-337-3p |
gagcctgATAGGAGaatgt |
1 |
CUCCUAUA | m7a | Created | -0.001000 | -0.001000 |
-0.050000 |
|
| hsa-miR-4279 |
gagcctgatAGGAGAatgt |
0 | CUCUCCUC | m6b | Created | no TS | -0.004000 |
-3.820000 |
|
| hsa-miR-4713-5p |
gagcctgaTGGGAGAAtgt |
5 |
UUCUCCCA | m8a | Disrupted | -0.198000 | no TS |
16.930000 |
|
| hsa-miR-532-3p |
gagcctgaTGGGAGaatgt |
7 |
CCUCCCAC | m6b | Disrupted | -0.035000 | no TS |
2.750000 |
|
| hsa-miR-629-3p |
gagcctgatGGGAGAAtgt |
6 |
GUUCUCCC | m7b | (m7b->m6c) | -0.040000 | no TS |
2.160000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.134843478C>T | COSN5119932 | HX19T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1183 |
tattgcctCTACAGTctgt |
0 | CACUGUAG | m7b | Created | no TS | 0.006000 |
-0.880000 |
|
| hsa-miR-3612 |
tatTGCCTCCacagtctgt |
0 | AGGAGGCA | m7b | (m7b->m6b) | -0.414000 | -0.223000 |
1.410000 |
|
| hsa-miR-4318 |
tattgcctCCACAGTctgt |
2 |
CACUGUGG | m7b | Disrupted | -0.371000 | -0.330000 |
0.080000 |
|
| hsa-miR-4443 |
tattGCCTCCAcagtctgt |
1 |
UUGGAGGC | m7b | Disrupted | -0.319000 | -0.216000 | No effect | |
| hsa-miR-650 |
tatTGCCTCCacagtctgt |
0 | AGGAGGCA | m7b | (m7b->m6b) | -0.457000 | -0.255000 |
1.460000 |
|
| hsa-miR-877-5p |
tattgCCTCTACagtctgt |
0 | GUAGAGGA | m7a | Created | NA | NA |
-0.530000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.134843553T>A | COSN9702454 | AOCS-086-3-2 | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-122-5p |
caagcACACTCCctcctgc |
0 | UGGAGUGU | m7b | Disrupted | 0.048000 | no TS |
-0.150000 |
|
| hsa-miR-3650 |
caagcACACACCctcctgc |
0 | AGGUGUGU | m7b | Created | no TS | 0.070000 | No effect | |
| hsa-miR-4419a |
caagcacaCTCCCTCctgc |
0 | UGAGGGAG | m7b | Disrupted | -0.163000 | -0.162000 | No effect | |
| hsa-miR-4455 |
caagcaCACACCCTcctgc |
0 | AGGGUGUG | m8a | Created | -0.197000 | -0.215000 |
-0.120000 |
|
| hsa-miR-4510 |
caagcacaCTCCCTCctgc |
0 | UGAGGGAG | m7b | Disrupted | -0.144000 | -0.153000 | No effect | |
| hsa-miR-574-5p |
caagCACACTCcctcctgc |
0 | UGAGUGUG | m7b | Disrupted | 0.062000 | no TS |
-3.670000 |
|
| hsa-miR-648 |
caaGCACACTccctcctgc |
0 | AAGUGUGC | m7b | (m7b->m6b) | 0.000000 | no TS |
0.090000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.134843889G>A | 8_3244 | 266395 | [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][myelodysplastic_syndrome] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-558 |
agcgtcaGCAGCTCcagag |
3 |
UGAGCUGC | m7b | Created | no TS | -0.05 | No effect | |
| hsa-miR-628-5p |
agcGTCAGCAgctccagag |
2 |
AUGCUGAC | m7b | (m6b->m7b) | no TS | 0.037 | No effect | |
| hsa-miR-93-3p |
agcgTCAGCAGctccagag |
2 |
ACUGCUGA | m7b | Created | no TS | 0.027 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.134844092G>T | COSN7558907 | 8064559 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1225-3p |
agcctgcGGGGCTCtggtg |
1 |
UGAGCCCC | m7b | Disrupted | -0.092000 | no TS |
0.450000 |
|
| hsa-miR-3663-3p |
agcctgcGGTGCTCtggtg |
0 | UGAGCACC | m7b | Created | no TS | -0.096000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.134844183C>T | COSN8296500 | PCSI_0083_Pa_P_526 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-34a-5p |
acaaaaCACTGCCAgcgtg |
2 |
UGGCAGUG | m8a | Created | -0.104000 | -0.393000 |
-3.420000 |
|
| hsa-miR-34c-5p |
acaaaaCACTGCCagcgtg |
2 |
AGGCAGUG | m7b | Created | -0.097000 | -0.386000 |
-2.600000 |
|
| hsa-miR-449a |
acaaaaCACTGCCAgcgtg |
2 |
UGGCAGUG | m8a | Created | -0.097000 | -0.428000 |
-5.320000 |
|
| hsa-miR-449b-5p |
acaaaaCACTGCCagcgtg |
2 |
AGGCAGUG | m7b | Created | -0.097000 | -0.428000 |
-5.320000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr9:g.134844321C>T | COSN5698555 | RK143_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-135a-5p |
aaagaaAAGCCATAgccga |
12 |
UAUGGCUU | m8a | Disrupted | -0.198000 | no TS |
3.910000 |
| hsa-miR-135b-5p |
aaagaaAAGCCATAgccga |
12 |
UAUGGCUU | m8a | Disrupted | -0.198000 | no TS |
3.930000 |
| hsa-miR-3119 |
aaagAAAAGCCAtagccga |
11 |
UGGCUUUU | m8a | Disrupted | -0.228000 | -0.045000 |
1.150000 |
| hsa-miR-5003-3p |
aaaGAAAAGTcatagccga |
7 |
UACUUUUC | m7b | (m6b->m7b) | 0.076000 | 0.023000 |
0.090000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 134842317 | rs12553247 | C | C |
hsa-miR-3940-3p |
21 |
cgagcCCGGGCTc |
Disrupted |
N |
No Change |
| T |
hsa-miR-3155a hsa-miR-3155b hsa-miR-484 |
21 21 21 |
cGAGCCTGggctc cGAGCCTGggctc cGAGCCTGggctc |
Created Created Created |
N N N |
No Change No Change No Change |
|||
| 134842464 | rs55951876 | G | G |
hsa-miR-4492 hsa-miR-4498 hsa-miR-4505 hsa-miR-4731-5p hsa-miR-5001-5p hsa-miR-5787 hsa-miR-7155-5p hsa-miR-762 |
2 2 2 2 2 2 2 2 |
accCCAGCCCgga accCCAGCCCgga acCCCAGCCcgga aCCCCAGCccgga accCCAGCCCgga acCCCAGCCcgga ACCCCAGcccgga accCCAGCCCgga |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N |
-0.111 -0.12 -0.12 -0.171 -0.111 -0.102 -0.073 -0.102 |
| C |
hsa-miR-4651 hsa-miR-608 hsa-miR-6742-5p hsa-miR-6756-5p hsa-miR-6766-5p hsa-miR-6784-5p hsa-miR-92a-2-5p |
2 2 2 2 2 2 2 |
accCCACCCCgga accCCACCCCgga ACCCCACcccgga acCCCACCCcgga acCCCACCCcgga accccaCCCCGGA aCCCCACCccgga |
Created Created Created Created Created Created Created |
N N N N N N N |
-0.145 -0.126 -0.115 -0.098 -0.107 -0.212 -0.124 |
|||
| 134842782 | rs184272423 | G | G |
hsa-miR-548ac hsa-miR-548ae hsa-miR-548ah-3p hsa-miR-548aj-3p hsa-miR-548am-3p hsa-miR-548aq-3p hsa-miR-548d-3p hsa-miR-548h-3p hsa-miR-548j-3p hsa-miR-548x-3p hsa-miR-548z |
9 9 9 9 9 9 9 9 9 9 9 |
gcctccGTTTTTA gcctccGTTTTTA gcctccGTTTTTA gcctccGTTTTTA gcctccGTTTTTA gcctccGTTTTTA gcctccGTTTTTA gcctccGTTTTTA gcctccGTTTTTA gcctccGTTTTTA gcctccGTTTTTA |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N N N |
0.099 0.102 0.102 0.102 0.102 0.102 0.092 0.099 0.095 0.102 0.099 |
| A |
hsa-miR-3612 hsa-miR-4443 hsa-miR-4694-3p hsa-miR-4802-5p hsa-miR-548c-3p hsa-miR-650 |
3 3 4 4 9 3 |
GCCTCCAttttta GCCTCCAttttta gccTCCATTTtta gCCTCCATtttta gcctccATTTTTA GCCTCCAttttta |
Created Created Created Created Created Created |
N N N N N N |
-0.172 -0.275 -0.004 -0.176 0.161 -0.162 |
|||
| 134842792 | rs142194317 | A | A |
hsa-miR-2053 hsa-miR-3689d hsa-miR-377-5p hsa-miR-6086 hsa-miR-6851-5p |
2 1 1 1 1 |
TTAACAAcctcca ttaacaACCTCCA ttaaCAACCTCca ttaaCAACCTCca ttaacaACCTCCA |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
0.039 -0.115 -0.162 -0.162 -0.118 |
| G |
hsa-miR-3612 hsa-miR-4443 hsa-miR-4687-3p hsa-miR-485-5p hsa-miR-650 hsa-miR-6884-5p |
1 1 2 1 1 1 |
ttaacaGCCTCCA ttaacaGCCTCCA ttAACAGCCtcca ttaaCAGCCTCca ttaacaGCCTCCA ttaaCAGCCTCca |
Created Created Created Created Created Created |
N N N N N N |
-0.147 -0.255 -0.173 -0.173 -0.144 -0.182 |
|||
| 134843036 | rs3196378 | C | C |
hsa-miR-1908-5p hsa-miR-3141 hsa-miR-4787-5p hsa-miR-663a hsa-miR-6752-5p hsa-miR-6787-5p hsa-miR-6842-5p hsa-miR-7110-5p |
2 2 2 8 3 8 3 3 |
cacCCCCGCCctg cacccCCGCCCTg cACCCCCGccctg cacCCCCGCCctg CACCCCCgccctg cacCCCCGCCctg CACCCCCgccctg CACCCCCgccctg |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N |
-0.178 -0.176 -0.131 -0.188 -0.092 -0.188 -0.082 -0.138 |
| A |
hsa-miR-342-5p hsa-miR-4446-3p hsa-miR-4492 hsa-miR-4498 hsa-miR-4505 hsa-miR-4651 hsa-miR-4664-5p hsa-miR-4731-5p hsa-miR-5001-5p hsa-miR-5787 hsa-miR-608 hsa-miR-6737-5p hsa-miR-6747-5p hsa-miR-6812-5p hsa-miR-6819-5p hsa-miR-7155-5p hsa-miR-762 |
3 10 9 9 8 3 3 2 2 2 3 3 3 3 3 2 2 |
CACCCCAgccctg cacccCAGCCCTg caccCCAGCCCtg caccCCAGCCCtg cacCCCAGCCctg CACCCCAgccctg CACCCCAgccctg caCCCCAGCcctg caccCCAGCCCtg cacCCCAGCCctg CACCCCAgccctg CACCCCAgccctg CACCCCAgccctg CACCCCAgccctg CACCCCAgccctg cACCCCAGccctg caccCCAGCCCtg |
Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created |
N N N N N N N N N N N N N N N N N |
-0.081 -0.056 -0.054 -0.091 -0.11 -0.152 -0.087 -0.098 -0.082 -0.147 -0.152 -0.048 -0.092 -0.058 -0.048 -0.045 -0.129 |
|||
| 134843575 | rs115807049 | C | C |
hsa-miR-181d-3p hsa-miR-3180 hsa-miR-3180-3p hsa-miR-3196 hsa-miR-4655-5p hsa-miR-6784-5p hsa-miR-6816-5p |
1 2 2 2 1 1 2 |
ccgcCCCGGTGcg CCGCCCCggtgcg CCGCCCCggtgcg CCGCCCCggtgcg ccgCCCCGGTgcg ccGCCCCGGtgcg CCGCCCCggtgcg |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N |
-0.032 -0.081 -0.09 -0.071 -0.086 -0.078 -0.071 |
| T |
hsa-miR-3141 hsa-miR-4685-5p hsa-miR-4733-3p hsa-miR-6753-5p hsa-miR-6837-5p |
2 1 1 1 1 |
CCGCCCTggtgcg ccGCCCTGGtgcg ccgcCCTGGTGcg ccgCCCTGGTgcg ccGCCCTGGtgcg |
Created Created Created Created Created |
N N N N N |
-0.103 0.002 0.088 0.036 0.021 |
|||
| 134843746 | rs10895 | G | G |
hsa-miR-337-5p hsa-miR-4724-5p hsa-miR-887-3p |
14 14 14 |
caAGCCGTTcagt caagccGTTCAGT caagCCGTTCAgt |
Disrupted Disrupted Disrupted |
N N N |
-0.158 0.065 -0.084 |
| A |
hsa-miR-135a-5p hsa-miR-135b-5p hsa-miR-4790-3p |
10 10 14 |
cAAGCCATtcagt cAAGCCATtcagt caagCCATTCAgt |
Created Created Created |
N N N |
0.029 0.029 0.005 |