SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001206955
Gene Symbol: CNTN4
Description: Homo sapiens contactin 4 (CNTN4), transcript variant 4, mRNA.
Gene Location: chr3(+):2280512-3099645
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr3:g.3056288C>A COSN1275826 HCC21T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4318 tgaagacaCACAGTactaa
 0 CACUGUGG m6b Created no TS -0.130000 -0.690000
hsa-miR-4455 tgaagACACCCagtactaa
 15
 AGGGUGUG m6b Disrupted -0.397000 -0.199000 No effect
hsa-miR-4693-5p tgaagacaCACAGTActaa
 0 AUACUGUG m7b Created no TS -0.248000 -0.010000
hsa-miR-609 tgaagACACCCagtactaa
 15
 AGGGUGUU m6b Disrupted -0.411000 -0.191000 No effect
hsa-miR-892a tgaagacACACAGTactaa
 0 CACUGUGU m7b Created no TS -0.354000 -1.150000
hsa-miR-4318 tgaagacaCACAGTactaa
 0 CACUGUGG m6b Created no TS -0.130000 -0.690000
hsa-miR-4455 tgaagACACCCagtactaa
 15
 AGGGUGUG m6b Disrupted -0.397000 -0.199000 No effect
hsa-miR-4693-5p tgaagacaCACAGTActaa
 0 AUACUGUG m7b Created no TS -0.248000 -0.010000
hsa-miR-609 tgaagACACCCagtactaa
 15
 AGGGUGUU m6b Disrupted -0.411000 -0.191000 No effect
hsa-miR-892a tgaagacACACAGTactaa
 0 CACUGUGU m7b Created no TS -0.354000 -1.150000
hsa-miR-4318 tgaagacaCACAGTactaa
 0 CACUGUGG m6b Created no TS -0.130000 -0.690000
hsa-miR-4455 tgaagACACCCagtactaa
 15
 AGGGUGUG m6b Disrupted -0.397000 -0.199000 No effect
hsa-miR-4693-5p tgaagacaCACAGTActaa
 0 AUACUGUG m7b Created no TS -0.248000 -0.010000
hsa-miR-609 tgaagACACCCagtactaa
 15
 AGGGUGUU m6b Disrupted -0.411000 -0.191000 No effect
hsa-miR-892a tgaagacACACAGTactaa
 0 CACUGUGU m7b Created no TS -0.354000 -1.150000
hsa-miR-4318 tgaagacaCACAGTactaa
 0 CACUGUGG m6b Created no TS -0.13 -0.69
hsa-miR-4455 tgaagACACCCagtactaa
 15
 AGGGUGUG m6b Disrupted -0.397 -0.199 No effect
hsa-miR-4693-5p tgaagacaCACAGTActaa
 0 AUACUGUG m7b Created no TS -0.248 -0.01
hsa-miR-609 tgaagACACCCagtactaa
 15
 AGGGUGUU m6b Disrupted -0.411 -0.191 No effect
hsa-miR-892a tgaagacACACAGTactaa
 0 CACUGUGU m7b Created no TS -0.354 -1.15


Mutation Mutation ID Sample Name Cancer Type
chr3:g.3056387C>A 9_105450 CRC-9-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr3:g.3056661G>T COSN6765447 RK197_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-106a-3p aaataaATTGCAaattact
 6
 CUGCAAUG m6b Disrupted -0.090000 no TS 0.060000
hsa-miR-203 aaataaATTTCAaattact
 12
 GUGAAAUG m6b Created 0.082000 0.068000 No effect
hsa-miR-450b-5p aaataaaTTGCAAAttact
 6
 UUUUGCAA m7b Disrupted -0.236000 -0.099000 0.180000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.3056981C>A COSN9719690 C0079T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-579 ttcactCAAATGAgttagc
 16
 UUCAUUUG m7b Created -0.013000 -0.039000 -0.060000
hsa-miR-644b-3p ttcactCAAATGAgttagc
 16
 UUCAUUUG m7b Created -0.013000 -0.020000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.3057021T>A COSN1945993 RK106_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5701 tcttaGACAATAAatttga
 13
 UUAUUGUC m8a Created -0.148000 -0.306000 No effect
hsa-miR-5701 tcttaGACAATAAatttga
 0 UUAUUGUC m8a Created -0.148 -0.306 No effect


Mutation Mutation ID Sample Name Cancer Type
chr3:g.3057584T>A COSN6574072 ICGC_MB125 [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr3:g.3057782T>G COSN9547858 AOCS-137-3-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-376c ggttactTCTATGTTgaaa
 19
 AACAUAGA m8a Disrupted -0.206000 no TS 0.120000
hsa-miR-548ao-5p ggTTACTTCTatgttgaaa
 14
 AGAAGUAA m8a (m8a->m7a) -0.121000 -0.094000 -0.550000
hsa-miR-548ax ggTTACTTCTatgttgaaa
 14
 AGAAGUAA m8a (m8a->m7a) -0.102000 -0.075000 1.620000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
3057776 rs11708737 T T hsa-miR-548ao-5p
hsa-miR-548ax
14
14
 tatggTTACTTCt
tatggTTACTTCt
 Disrupted
Disrupted
N
N
 -0.121
-0.102
C hsa-miR-591
13
 tATGGTCActtct
 Created
N
 -0.161
3057858 rs187891461 C C hsa-miR-4292
hsa-miR-4455
hsa-miR-609
hsa-miR-6742-3p
hsa-miR-6772-5p
hsa-miR-6776-5p
hsa-miR-6791-5p
3
2
2
2
2
2
3
 atgacaCCCAGGG
atgACACCCAggg
atgACACCCAggg
atgacACCCAGGg
atgACACCCAggg
atgaCACCCAGgg
atgacaCCCAGGG
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
 -0.311
-0.199
-0.191
-0.206
-0.185
-0.221
-0.304
A hsa-miR-323b-5p
hsa-miR-410-5p
hsa-miR-494-5p
hsa-miR-6755-3p
2
2
2
2
 atGACAACCAggg
atGACAACCAggg
atGACAACCAggg
aTGACAACcaggg
 Created
Created
Created
Created
N
N
N
N
 -0.453
-0.453
-0.453
-0.288

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