SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001256567
Gene Symbol: CHRNB4
Description: Homo sapiens cholinergic receptor, nicotinic, beta 4 (CHRNB4), mRNA.
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Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr15:g.78624356C>A COSN1180638 HCC90T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4493 ctgagaGGCCTTCcctaac
 0 AGAAGGCC m7b Disrupted -0.453000 -0.227000 5.160000
hsa-miR-4747-5p ctgagaggCCTTCCCTaac
 0 AGGGAAGG m8a Disrupted -0.684000 -0.524000 No effect
hsa-miR-4757-5p ctgAGAGGCCTtccctaac
 0 AGGCCUCU m8a Disrupted -0.202000 no TS 5.890000
hsa-miR-5196-5p ctgagaggCCTTCCCTaac
 0 AGGGAAGG m8a Disrupted -0.753000 -0.556000 No effect
hsa-miR-4493 ctgagaGGCCTTCcctaac
 0 AGAAGGCC m7b Disrupted -0.453000 -0.227000 5.160000
hsa-miR-4747-5p ctgagaggCCTTCCCTaac
 0 AGGGAAGG m8a Disrupted -0.684000 -0.524000 No effect
hsa-miR-4757-5p ctgAGAGGCCTtccctaac
 0 AGGCCUCU m8a Disrupted -0.202000 no TS 5.890000
hsa-miR-5196-5p ctgagaggCCTTCCCTaac
 0 AGGGAAGG m8a Disrupted -0.753000 -0.556000 No effect
hsa-miR-4493 ctgagaGGCCTTCcctaac
 0 AGAAGGCC m7b Disrupted -0.453 -0.227 5.16
hsa-miR-4747-5p ctgagaggCCTTCCCTaac
 0 AGGGAAGG m8a Disrupted -0.684 -0.524 No effect
hsa-miR-4757-5p ctgAGAGGCCTtccctaac
 0 AGGCCUCU m8a Disrupted -0.202 no TS 5.89
hsa-miR-5196-5p ctgagaggCCTTCCCTaac
 0 AGGGAAGG m8a Disrupted -0.753 -0.556 No effect

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78624383G>A COSN5401160 RK172_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-186-5p ccATTCTTTGctccaatgt
 0 CAAAGAAU m8a (m8a->m7b) 0.062000 -0.010000 No effect
hsa-miR-3198 ccattctttACTCCAatgt
 0 GUGGAGUC m6b Created no TS -0.159000 -5.780000
hsa-miR-4309 ccattctttACTCCAatgt
 0 CUGGAGUC m6b Created no TS -0.149000 -0.700000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78624514A>G ICGC_8A8D4AE4-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4530 caaagTGCTGGGattacaa
 0 CCCAGCAG m7a Created NA NA -8.19
hsa-miR-4733-5p caaagtgcTGGGATTacaa
 0 AAUCCCAA m7a Created NA NA -0.85

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78624754C>G COSN7249436 8066491 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4795-5p cacaCACTTCTagattctt
 0 AGAAGUGG m7a Disrupted -0.133000 -0.133000 0.690000
hsa-miR-595 caCACACTTCtagattctt
 0 GAAGUGUG m8a (m8a->m7b) -0.136000 -0.136000 0.350000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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