SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_145862 |
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Gene Symbol: | CHEK2 |
Description: | Homo sapiens checkpoint kinase 2 (CHEK2), transcript variant 3, mRNA. |
Gene Location: | chr22(-):29083730-29137822 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
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chr22:g.28687854C>G | COSN8612538 | 202_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-128 |
tctttCACTGTGtcatctt |
0 | UCACAGUG | m7b | Created | no TS | -0.262000 |
-5.350000 |
hsa-miR-3681-3p |
tctttCACTGTGTcatctt |
0 | ACACAGUG | m8a | Created | no TS | -0.234000 |
-7.920000 |
hsa-miR-425-5p |
tctttcactGTGTCATctt |
0 | AAUGACAC | m7b | (m6b->m7b) | no TS | -0.205000 |
-0.690000 |
hsa-miR-4797-5p |
tctttcACTCTGTCatctt |
0 | GACAGAGU | m8a | Disrupted | -0.182000 | no TS |
4.790000 |
hsa-miR-5586-3p |
tcttTCACTCTGtcatctt |
1 |
CAGAGUGA | m8a | Disrupted | -0.240000 | no TS |
8.220000 |
hsa-miR-642a-3p |
tctttcacTGTGTCatctt |
0 | AGACACAU | m6b | Created | no TS | -0.166000 |
-14.920000 |
hsa-miR-642b-3p |
tctttcacTGTGTCatctt |
0 | AGACACAU | m6b | Created | no TS | -0.166000 |
-14.620000 |
hsa-miR-759 |
tctttCACTCTGtcatctt |
1 |
GCAGAGUG | m7b | Disrupted | -0.258000 | no TS |
5.030000 |