SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_025134
Gene Symbol:	CHD9
Description:	Homo sapiens chromodomain helicase DNA binding protein 9 (CHD9), mRNA.
Gene Location:	chr16(+):53088944-53361414
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr16:g.53325166A>G			COSN6086596		RK193_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-335-3p	tttATGAAAAttatgctca	15	UUUUUCAU	m7b	(m7b->m6b)	0.009000	0.103000	0.300000
hsa-miR-4775	tttatgAAAATTAtgctca	6	UUAAUUUU	m7b	Disrupted	0.286000	0.248000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr16:g.53325608T>G			COSN6086597		RK070_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-574-3p	ttgcTGAGCGTaattcaga	0	CACGCUCA	m7b	Created	no TS	-0.395000	-0.030000
hsa-miR-99a-3p	ttgctGAGCTTaattcaga	8	CAAGCUCG	m6b	Disrupted	-0.120000	no TS	-2.920000
hsa-miR-99b-3p	ttgctGAGCTTaattcaga	8	CAAGCUCG	m6b	Disrupted	-0.120000	no TS	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr16:g.53326345A>C			COSN5835225		HX27T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-491-3p	aaggGCATAAatttagggg	1	CUUAUGCA	m6b	Disrupted	0.020000	no TS	0.700000
hsa-miR-675-3p	aaggGCATACAtttagggg	0	CUGUAUGC	m7b	Created	no TS	-0.018000	-4.110000

Mutation			Mutation ID		Sample Name		Cancer Type
chr16:g.53327369G>A			COSN7260289		8066067		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-151a-3p	gtgtAGTCTAaatttgctt	1	CUAGACUG	m6b	Created	-0.161000	-0.286000	-0.930000
hsa-miR-32-3p	gtgtagtCTAAATTtgctt	12	CAAUUUAG	m7b	Created	0.187000	0.174000	No effect
hsa-miR-4494	gtgtAGTCTGaatttgctt	11	CCAGACUG	m6b	Disrupted	-0.137000	no TS	0.880000
hsa-miR-499b-5p	gtgtAGTCTGaatttgctt	11	ACAGACUU	m6b	Disrupted	-0.164000	-0.031000	5.260000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
53327154	rs186531692	G
			A	hsa-miR-4775 hsa-miR-590-3p	12 12	tgtAAAATTAAgg tgTAAAATTAagg	Created Created	N N	0.087 0.088

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