SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_078487 |
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Gene Symbol: | CDKN2B |
Description: | Homo sapiens cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (CDKN2B), transcript variant 1, mRNA. |
Gene Location: | chr9(-):22002901-22009312 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.22003611T>- | ICGC_sm163541 | RK046_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.22003887A>T | 9_31913 | CRC-4-Tumor | Colorectal adenocarcinoma | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr9:g.22006037T>T | ICGC_59229 | TCGA-G2-A2EK-01A-22D-A18F-08 | BladderUrothelialCarcinoma(TCGA,US) | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4268 |
gccGAGGAGCggggccacc |
0 | GGCUCCUC | m7b | (m7b->m6c) | -0.172 | -0.114 | No effect |
hsa-miR-4286 |
gccgaggAGTGGGGccacc |
0 | ACCCCACU | m7b | Created | no TS | -0.063 |
-3.2 |
hsa-miR-4758-3p |
gccgaggaGTGGGGCcacc |
0 | UGCCCCAC | m7b | Created | no TS | -0.179 |
-0.05 |
hsa-miR-483-3p |
gccgAGGAGTGgggccacc |
0 | UCACUCCU | m7b | Created | -0.251 | -0.274 |
-0.01 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
22006042 | rs191233212 | A | A |
hsa-miR-4268 |
8 |
tggccGAGGAGCg |
Disrupted |
N |
-0.058 |