SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_017774
Gene Symbol: CDKAL1
Description: Homo sapiens CDK5 regulatory subunit associated protein 1-like 1 (CDKAL1), mRNA.
Gene Location: chr6(+):20534687-21232634
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr6:g.21231109C>T COSN167702 GC8_T [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3124-3p acAGGAAAGTgacatctcc
 4
 ACUUUCCU m8a (m7a->m8a) -0.123000 -0.151000 0.110000
hsa-miR-4315 acagGAAAGCGacatctcc
 1
 CCGCUUUC m7b Disrupted -0.440000 no TS 2.090000
hsa-miR-4790-5p acaggAAAGCGAcatctcc
 1
 AUCGCUUU m7b Disrupted -0.259000 no TS 2.100000
hsa-miR-3124-3p acAGGAAAGTgacatctcc
 0 ACUUUCCU m8a (m7a->m8a) -0.123 -0.151 0.11
hsa-miR-4315 acagGAAAGCGacatctcc
 1
 CCGCUUUC m7b Disrupted -0.44 no TS 2.09
hsa-miR-4790-5p acaggAAAGCGAcatctcc
 1
 AUCGCUUU m7b Disrupted -0.259 no TS 2.1

Mutation Mutation ID Sample Name Cancer Type
chr6:g.21231169A>C COSN8314804 TCGA-A8-A0A6-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-185-3p ttctCAGCCCCTcttctta
 0 AGGGGCUG m8a Created no TS -0.239000 -0.010000
hsa-miR-3184-5p ttctcaGCCCCTCttctta
 0 UGAGGGGC m7b Created no TS -0.304000 -1.350000
hsa-miR-423-5p ttctcaGCCCCTCttctta
 0 UGAGGGGC m7b Created no TS -0.304000 -4.240000
hsa-miR-4656 ttcTCAGCCCctcttctta
 2
 UGGGCUGA m7b (m6b->m7b) -0.185000 -0.444000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr6:g.21231528A>G ICGC_9FF0C492-2A78-11E2-8335-12FD496BB9B8 CPCG_0102_Pr_P_P2 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5707 tgggtTCAAACGattctcc
 2
 ACGUUUGA m7b Disrupted -0.259 no TS 0.21

Mutation Mutation ID Sample Name Cancer Type
chr6:g.21231697A>G ICGC_7A2313A0-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4530 caaagTGCTGGGattacag
 0 CCCAGCAG m7a Created NA NA -0.1
hsa-miR-4733-5p caaagtgcTGGGATTacag
 0 AAUCCCAA m7a Created NA NA -0.01

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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