SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_053056
Gene Symbol: CCND1
Description: Homo sapiens cyclin D1 (CCND1), mRNA.
Gene Location: chr11(+):69455872-69469242
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr11:g.69651520A>G COSN9031603 8051717 [pancreas][NS][carcinoid-endocrine_tumour][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.69651761A>G COSN8689115 AOCS-088-3-8 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3127-3p aagtaGAAGGGGgttttag
 0 UCCCCUUC m7b Created 0.085000 -0.165000 -5.980000
hsa-miR-4640-3p aagtagaAGGGGGTtttag
 0 CACCCCCU m7b Created no TS -0.320000 -2.690000
hsa-miR-877-3p aagtaGAAGAGGgttttag
 13
 UCCUCUUC m7b Disrupted -0.196000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.69653168T>G COSN15333221 SNU_09_S1 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1228-3p gggaggAGGTGTGAggagg
 2
 UCACACCU m8a Disrupted 0.042000 no TS 6.040000
hsa-miR-1306-5p gggaGGAGGTGtgaggagg
 2
 CCACCUCC m7b Disrupted -0.044000 -0.057000 3.510000
hsa-miR-342-3p gggaggagGTGTGAGgagg
 0 UCUCACAC m7b Disrupted 0.192000 0.101000 6.200000
hsa-miR-4667-3p gggAGGAGGGgtgaggagg
 3
 UCCCUCCU m7b (m6b->m7b) -0.172000 -0.124000 -10.200000
hsa-miR-1228-3p gggaggAGGTGTGAggagg
 2
 UCACACCU m8a Disrupted 0.042000 no TS 6.040000
hsa-miR-1306-5p gggaGGAGGTGtgaggagg
 2
 CCACCUCC m7b Disrupted -0.044000 -0.057000 3.510000
hsa-miR-342-3p gggaggagGTGTGAGgagg
 0 UCUCACAC m7b Disrupted 0.192000 0.101000 6.200000
hsa-miR-4667-3p gggAGGAGGGgtgaggagg
 3
 UCCCUCCU m7b (m6b->m7b) -0.172000 -0.124000 -10.200000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.69653190G>A COSN8584632 J30_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4279 ctcccGAGGAGAaggggcg
 0 CUCUCCUC m7b Created no TS 0.121000 0.110000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
69652450 rs183243879 G G hsa-miR-1224-3p
hsa-miR-1306-5p
2
2
 ggAGGTGGGgtgt
GGAGGTGgggtgt
 Disrupted
Disrupted
N
N
 0.013
-0.021
69653116 rs78871738 A A hsa-miR-1306-5p
hsa-miR-4287
hsa-miR-4685-3p
hsa-miR-5088-3p
8
7
7
11
 gaagGGAGGTGgc
gAAGGGAGgtggc
gAAGGGAGgtggc
GAAGGGAggtggc
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 -0.036
-0.011
0.017
0.014
G hsa-miR-3127-3p
hsa-miR-6756-3p
11
11
 GAAGGGGggtggc
GAAGGGGggtggc
 Created
Created
N
N
 -0.062
-0.052

Genome Browser