| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_145200 |
|---|---|
| Gene Symbol: | CABP4 |
| Description: | Homo sapiens calcium binding protein 4 (CABP4), mRNA. |
| Gene Location: | chr11(+):67222817-67229245 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr11:g.67459136G>A | COSN5917089 | RK308_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1343 |
ttgagCCCAGGAGtgcaag |
1 |
CUCCUGGG | m8a | Disrupted | -0.303000 | -0.201000 | No effect | |
| hsa-miR-3187-5p |
ttgaGCCCAGGagtgcaag |
1 |
CCUGGGCA | m7a | Disrupted | -0.070000 | -0.070000 |
0.020000 |
|
| hsa-miR-378g |
ttgAGCCCAGgagtgcaag |
1 |
ACUGGGCU | m7b | (m7b->m6b) | -0.445000 | -0.334000 |
0.080000 |
|
| hsa-miR-4674 |
ttGAGCCCAGgagtgcaag |
1 |
CUGGGCUC | m8a | (m8a->m7a) | -0.339000 | -0.517000 |
-0.750000 |
|
| hsa-miR-483-3p |
ttgagcccAGGAGTGcaag |
1 |
UCACUCCU | m7b | Disrupted | -0.073000 | no TS |
0.700000 |
|
| hsa-miR-635 |
ttgaGCCCAAGagtgcaag |
0 | ACUUGGGC | m7b | Created | no TS | -0.306000 |
-0.060000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr11:g.67459515C>A | COSN15082637 | SM-4B296 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1291 |
acagatgttCAGGGCCcag |
2 |
UGGCCCUG | m7b | (m7b->m6c) | -0.251000 | -0.091000 |
3.040000 |
|
| hsa-miR-302c-5p |
acagATGTTAAgggcccag |
1 |
UUUAACAU | m7b | Created | 0.078000 | 0.207000 | No effect | |
| hsa-miR-3143 |
acagATGTTAagggcccag |
0 | AUAACAUU | m6b | Created | no TS | 0.098000 |
-5.770000 |
|
| hsa-miR-345-3p |
acagatgTTCAGGGCccag |
3 |
GCCCUGAA | m8a | Disrupted | -0.024000 | no TS |
0.020000 |
|
| hsa-miR-938 |
acagatgtTAAGGGCccag |
0 | UGCCCUUA | m7b | Created | no TS | -0.097000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr11:g.67459516A>G | COSN15122750 | SM-4B296 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1291 |
cagatgttCAGGGCCcaga |
2 |
UGGCCCUG | m7b | Disrupted | -0.251000 | -0.091000 |
3.440000 |
|
| hsa-miR-296-5p |
cagatgttcGGGGCCCaga |
1 |
AGGGCCCC | m7b | (m6c->m7b) | -0.142000 | -0.369000 |
-0.440000 |
|
| hsa-miR-345-3p |
cagatgTTCAGGGCccaga |
3 |
GCCCUGAA | m8a | Disrupted | -0.024000 | no TS |
0.020000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr11:g.67460797A>G | COSN8282899 | PCSI_0083_Pa_P_526 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1208 |
ctggctaacACAGTGAaac |
0 | UCACUGUU | m7a | (m7a->m6b) | -0.035000 | no TS |
1.090000 |
|
| hsa-miR-3152-3p |
ctggCTAACACAgtgaaac |
0 | UGUGUUAG | m8a | Disrupted | -0.029000 | no TS |
0.050000 |
|
| hsa-miR-4318 |
ctggctaaCACAGTGaaac |
0 | CACUGUGG | m7a | Disrupted | NA | NA | No effect | |
| hsa-miR-892a |
ctggctaACACAGTGaaac |
0 | CACUGUGU | m8a | Disrupted | -0.044000 | no TS | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr11:g.67461203G>C | COSN5917090 | RK175_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1229 |
ctgaGGTGAGAGgatcatt |
1 |
CUCUCACC | m8a | Disrupted | -0.133000 | 0.017000 | No effect | |
| hsa-miR-3183 |
ctgaggtGAGAGGatcatt |
2 |
GCCUCUCU | m6b | Disrupted | -0.170000 | -0.106000 | No effect | |
| hsa-miR-4421 |
ctgaggtGACAGGatcatt |
0 | ACCUGUCU | m6b | Created | no TS | -0.078000 |
-0.050000 |
|
| hsa-miR-4723-3p |
ctgaggtGAGAGGatcatt |
2 |
CCCUCUCU | m6b | Disrupted | -0.190000 | -0.106000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr11:g.67461640G>A | COSN8688406 | AOCS-166-1-2 | [ovary][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-4756-3p |
gaggctttgATCTCTGttg |
0 | CCAGAGAU | m7b | (m6c->m7b) | no TS | -0.161000 |
-0.010000 |
| hsa-miR-4786-5p |
gaggcttTGGTCTCtgttg |
0 | UGAGACCA | m7b | Disrupted | -0.204000 | no TS | No effect |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 67459006 | rs143907498 | A | A |
hsa-miR-3183 hsa-miR-4723-3p hsa-miR-5196-3p hsa-miR-6769b-3p hsa-miR-7111-3p |
2 2 2 2 2 |
GAGAGGAtggctg GAGAGGAtggctg gaGAGGATGgctg GAGAGGAtggctg GAGAGGAtggctg |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
-0.106 -0.106 -0.117 -0.106 -0.103 |
| C |
hsa-miR-3194-5p hsa-miR-6819-3p hsa-miR-6849-3p hsa-miR-6858-3p hsa-miR-6877-3p |
2 2 2 2 2 |
gagaGGCTGGCtg gAGAGGCTggctg gagAGGCTGGctg gagagGCTGGCTg gAGAGGCTggctg |
Created Created Created Created Created |
N N N N N |
-0.223 -0.091 -0.124 -0.15 -0.091 |
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| 67459525 | rs189731301 | A | A |
hsa-miR-1285-3p hsa-miR-3187-5p hsa-miR-326 hsa-miR-330-5p hsa-miR-378g hsa-miR-4436b-5p hsa-miR-4486 hsa-miR-514a-5p hsa-miR-5189-5p hsa-miR-612 hsa-miR-6509-3p hsa-miR-6777-3p hsa-miR-6860 |
1 1 1 1 1 4 1 1 1 1 4 1 1 |
GCCCAGAgtggaa GCCCAGAgtggaa gCCCAGAGtggaa gCCCAGAGtggaa GCCCAGAgtggaa gcccagAGTGGAA GCCCAGAgtggaa gcCCAGAGTggaa GCCCAGAgtggaa GCCCAGAgtggaa gcccagAGTGGAA gcccAGAGTGGAa GCCCAGAgtggaa |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N N N N N |
-0.07 -0.07 -0.04 -0.04 -0.077 -0.031 -0.098 -0.028 -0.07 -0.083 -0.021 -0.164 -0.073 |
| G |
hsa-miR-3620-3p hsa-miR-4292 hsa-miR-6791-5p hsa-miR-939-3p |
1 1 1 1 |
gccCAGGGTGgaa gCCCAGGGtggaa gCCCAGGGtggaa GCCCAGGgtggaa |
Created Created Created Created |
N N N N |
-0.058 -0.091 -0.081 -0.077 |