SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001008404
Gene Symbol: C14orf180
Description: Homo sapiens chromosome 14 open reading frame 180 (C14orf180), mRNA.
Gene Location: chr14(+):105046055-105056183
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr14:g.104589211A>G COSN7429702 8057528 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-27a-5p aggaggcAAGCCCagcctt
0 AGGGCUUA m6b Created no TS -0.093000 No effect
hsa-miR-378g aggaggcaAGCCCAGcctt
1
ACUGGGCU m7b Created -0.178000 -0.306000 No effect
hsa-miR-5087 aggaggCAAACCCagcctt
0 GGGUUUGU m7a Disrupted NA NA -0.150000
hsa-miR-5589-5p aggaggcaaACCCAGCCtt
2
GGCUGGGU m8a (m8a->m7b) -0.402000 -0.230000 -0.010000

Mutation Mutation ID Sample Name Cancer Type
chr14:g.104589236G>T COSN8588014 2734_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4286 ttatggcttGTGGGGaatc
1
ACCCCACU m6b Disrupted -0.139000 no TS 3.190000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
104589344 rs191863595 C C hsa-miR-1229-5p
hsa-miR-197-5p
hsa-miR-3132
hsa-miR-4505
hsa-miR-5589-5p
hsa-miR-5787
hsa-miR-6861-5p
1
1
1
2
2
2
1
cccCTACCCAgcc
cccCTACCCAgcc
cccCTACCCAgcc
cccctaCCCAGCC
cccctACCCAGCc
cccctaCCCAGCC
ccccTACCCAGcc
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
-0.029
-0.069
-0.062
-0.121
-0.065
-0.159
-0.02
G hsa-miR-4794
hsa-miR-5580-5p
hsa-miR-6069
hsa-miR-664a-5p
1
2
1
1
ccccTAGCCAGcc
cccctAGCCAGCc
ccCCTAGCCAgcc
ccccTAGCCAGcc
Created
Created
Created
Created
N
N
N
N
0.008
-0.098
-0.223
0.027

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