SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_153714
Gene Symbol: C10orf67
Description: Homo sapiens chromosome 10 open reading frame 67 (C10orf67), mRNA.
Gene Location: chr10(-):23605519-23633772
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr10:g.23316611A>G COSN8183164 ASHPC_0006_Pa_P [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4461 tgttgCTCAATaaagcacc
 1
 GAUUGAGA m6b Disrupted -0.104000 no TS 8.870000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.23317315C>G COSN1116995 HCC119T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1286 aagtgcctaGTCCTGCtgc
 1
 UGCAGGAC m7b (m6b->m7b) -0.182000 -0.273000 No effect
hsa-miR-4433-3p aagtgcctACTCCTGctgc
 2
 ACAGGAGU m7b Disrupted -0.029000 -0.025000 -0.870000
hsa-miR-4722-5p aagtgcctaCTCCTGCtgc
 1
 GGCAGGAG m7b (m7b->m6b) -0.582000 -0.515000 No effect
hsa-miR-4759 aagtgccTAGTCCTgctgc
 0 UAGGACUA m7b Created no TS 0.023000 -3.800000
hsa-miR-1286 aagtgcctaGTCCTGCtgc
 0 UGCAGGAC m7b (m6b->m7b) -0.182 -0.273 No effect
hsa-miR-4433-3p aagtgcctACTCCTGctgc
 0 ACAGGAGU m7b Disrupted -0.029 -0.025 -0.87
hsa-miR-4722-5p aagtgcctaCTCCTGCtgc
 0 GGCAGGAG m7b (m7b->m6b) -0.582 -0.515 No effect
hsa-miR-4759 aagtgccTAGTCCTgctgc
 0 UAGGACUA m7b Created no TS 0.023 -3.8

Mutation Mutation ID Sample Name Cancer Type
chr10:g.23317858T>A COSN1482650 RK189_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1299 ccttagcaTTCCAGAgtgc
 2
 UUCUGGAA m7b Disrupted 0.003000 no TS No effect
hsa-miR-3673 ccttagCATTCCAgagtgc
 2
 AUGGAAUG m7b Disrupted 0.023000 no TS 0.010000
hsa-miR-4774-5p ccttagcATACCAGAgtgc
 0 UCUGGUAU m8a Created no TS -0.064000 -1.050000
hsa-miR-518c-5p ccttagcatTCCAGAGtgc
 1
 UCUCUGGA m7b (m7b->m6b) -0.111000 -0.030000 No effect
hsa-miR-613 ccttagCATTCCagagtgc
 2
 AGGAAUGU m6b Disrupted 0.020000 no TS 0.030000
hsa-miR-875-3p ccttagcaTTCCAGagtgc
 2
 CCUGGAAA m6b Disrupted 0.032000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.23317957G>A COSN9201578 AOCS-166-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-582-3p gcacacCCAGTTAatttaa
 2
 UAACUGGU m7a Disrupted -0.060000 no TS 0.280000


Mutation Mutation ID Sample Name Cancer Type
chr10:g.23318012C>T COSN1482651 RK062_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr10:g.23318721C>A COSN8639507 J46_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1207-3p agttacttgCAGCTGAaaa
 1
 UCAGCUGG m7a (m7a->m6a) -0.262000 -0.140000 No effect
hsa-miR-1297 agtTACTTGAAgctgaaaa
 0 UUCAAGUA m8a Created no TS -0.198000 -0.630000
hsa-miR-2276 agttaCTTGCAGctgaaaa
 2
 UCUGCAAG m7b Disrupted -0.497000 -0.298000 0.230000
hsa-miR-26a-5p agtTACTTGAAgctgaaaa
 0 UUCAAGUA m8a Created no TS -0.198000 -1.230000
hsa-miR-26b-5p agtTACTTGAAgctgaaaa
 0 UUCAAGUA m8a Created no TS -0.198000 -0.870000
hsa-miR-4465 agtTACTTGAagctgaaaa
 0 CUCAAGUA m7b (m6c->m7b) no TS -0.229000 -4.630000
hsa-miR-5697 agtTACTTGAagctgaaaa
 0 UCAAGUAG m7a (m6b->m7a) no TS -0.055000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
23317032 rs180787949 T C hsa-miR-6746-5p
hsa-miR-6771-5p
hsa-miR-6827-5p
0 ggCTCCCGAgtgg
ggCTCCCGAgtgg
GGCTCCCgagtgg
 Created
Created
Created
N
N
N
 -0.148
-0.157
-0.192
T hsa-miR-3664-3p
hsa-miR-4433-3p
hsa-miR-4459
hsa-miR-4768-3p
hsa-miR-510-5p
0 ggcTCCTGAGtgg
ggCTCCTGAgtgg
ggCTCCTGAgtgg
ggCTCCTGAgtgg
ggctCCTGAGTgg
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
 -0.025
-0.052
-0.032
-0.035
-0.102
23318178 rs184223997 C C hsa-miR-425-3p
hsa-miR-4785
1
2
 aaTTCCCGActca
aattcCCGACTCA
 Disrupted
Disrupted
N
N
 -0.244
-0.431
A hsa-miR-1299
hsa-miR-6128
hsa-miR-627-5p
hsa-miR-875-3p
hsa-miR-924
1
1
2
1
2
 aaTTCCAGActca
aATTCCAGActca
aattccAGACTCA
aaTTCCAGActca
aattccAGACTCA
 Created
Created
Created
Created
Created
N
N
N
N
N
 -0.117
-0.16
-0.133
-0.037
-0.096
23318263 rs4603206 G G hsa-miR-1207-3p
hsa-miR-6868-5p
hsa-miR-885-3p
1
1
1
 CCAGCTGccagcc
ccagCTGCCAGcc
ccaGCTGCCAgcc
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.14
-0.087
-0.116
A hsa-miR-133a-5p
1
 ccagcTACCAGCc
 Created
N
 -0.119

Genome Browser