SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_014753
Gene Symbol: BMS1
Description: Homo sapiens BMS1 homolog, ribosome assembly protein (yeast) (BMS1), mRNA.
Gene Location: chr10(+):43277953-43330385
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr10:g.42831203A>C COSN6970583 8033510 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4524a-3p gctcaagagCTGTCTCtac
2
UGAGACAG m7b (m6c->m7b) -0.041000 -0.199000 -0.460000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.42831457A>G COSN6071434 RK191_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-944 tttgtggATAATTatttat
2
AAAUUAUU m6b Disrupted 0.057000 no TS 0.030000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.42831782G>A COSN1489244 RK033_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5580-3p aaggaaatCATATGTatca
2
CACAUAUG m7b Created -0.006000 -0.076000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.42832025T>C COSN8185379 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-297 tcacACATACAacaatcag
0 AUGUAUGU m7b Created no TS -0.037000 -0.390000
hsa-miR-3149 tcacaCATACAAcaatcag
0 UUUGUAUG m7b Created no TS -0.021000 -0.030000
hsa-miR-3613-5p tcacacaTACAACAatcag
2
UGUUGUAC m7a Created 0.096000 0.087000 -0.110000
hsa-miR-567 tcacACATACaacaatcag
0 AGUAUGUU m6b Created no TS -0.011000 -0.030000
hsa-miR-675-3p tcacaCATACAacaatcag
0 CUGUAUGC m6b Created no TS -0.003000 -0.060000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.42832325T>C COSN6970584 8036161 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4777-3p ttgggaggcTGAGGTAgga
2
AUACCUCA m7b (m7b->m6c) 0.065000 no TS 1.520000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.42833078G>C COSN8933038 SS6003149 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-149-5p ttttAGCCAGAagagtgga
1
UCUGGCUC m7a Disrupted -0.038000 no TS No effect
hsa-miR-3064-5p ttttAGCCAGAagagtgga
1
UCUGGCUG m7a Disrupted -0.023000 no TS 0.010000
hsa-miR-3182 ttttagcCAGAAGagtgga
1
GCUUCUGU m6b Disrupted -0.008000 -0.063000 0.720000
hsa-miR-4474-3p ttttAGCCACAAgagtgga
0 UUGUGGCU m8a Created no TS -0.127000 -0.890000
hsa-miR-4794 tttTAGCCAGAagagtgga
1
UCUGGCUA m8a Disrupted -0.096000 no TS 4.620000
hsa-miR-664-5p tttTAGCCAGaagagtgga
1
ACUGGCUA m7b (m7b->m6b) -0.127000 no TS 0.130000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.42833241C>T COSN10067806 C0094T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7a-3p aaaagtTTGTATAttaaga
2
CUAUACAA m7b Created 0.036000 0.072000 -0.600000
hsa-let-7b-3p aaaagtTTGTATAttaaga
2
CUAUACAA m7b Created 0.055000 0.081000 -1.020000
hsa-let-7f-1-3p aaaagtTTGTATAttaaga
2
CUAUACAA m7b Created 0.036000 0.062000 -0.100000
hsa-miR-1277-5p aaaagtttgTATATTaaga
2
AAAUAUAU m6b Created 0.344000 0.488000 -0.010000
hsa-miR-4517 aaaagtttgCATATTaaga
4
AAAUAUGA m6b Disrupted 0.050000 -0.028000 0.010000
hsa-miR-4666a-3p aaaagtTTGTATattaaga
1
CAUACAAU m6b Created 0.119000 0.214000 -0.010000
hsa-miR-5583-3p aaaagtttgCATATTaaga
1
GAAUAUGG m6b Disrupted 0.074000 no TS 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.42833246T>C COSN10067807 C0094T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-190a tttgCATATCAagattatt
2
UGAUAUGU m7a Created -0.155000 -0.147000 -0.030000
hsa-miR-190b tttgCATATCAagattatt
2
UGAUAUGU m7a Created -0.155000 -0.147000 No effect
hsa-miR-4517 tttgCATATTaagattatt
4
AAAUAUGA m6b Disrupted 0.050000 -0.026000 0.010000
hsa-miR-5583-3p tttgCATATTaagattatt
1
GAAUAUGG m6b Disrupted 0.074000 no TS 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.42833328G>T COSN8530570 tumor_4133511 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-412 atttttattGGTGAAGgtt
1
ACUUCACC m7b (m7b->m6c) -0.043000 no TS No effect
hsa-miR-4719 atttttATTTGTGAaggtt
2
UCACAAAU m8a Created 0.070000 0.171000 -1.020000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.42833490T>A COSN1489245 RK037_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1225-3p cctGGGCTCAatggtatgg
0 UGAGCCCC m7a (m6a->m7a) no TS -0.043000 -0.050000
hsa-miR-1233 cctGGGCTCAatggtatgg
0 UGAGCCCU m7a (m6a->m7a) no TS -0.035000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.42833645G>A COSN6970585 8036161 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3619-3p gccatatacATGGTCCatc
0 GGGACCAU m7b (m6c->m7b) -0.065000 -0.116000 -2.000000
hsa-miR-591 gccatataCATGGTCcatc
0 AGACCAUG m7b Created no TS -0.080000 -0.430000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
42831808 rs111535934 G G hsa-miR-369-3p
hsa-miR-4681
hsa-miR-6082
3
2
2
cttcccGTATTAT
cTTCCCGTAttat
cttccCGTATTAt
Disrupted
Disrupted
Disrupted
N
N
N
0.101
-0.318
-0.053
A hsa-miR-4517
hsa-miR-4747-5p
hsa-miR-5196-5p
hsa-miR-5583-3p
hsa-miR-5692b
hsa-miR-5692c
hsa-miR-6871-5p
2
2
2
2
3
3
2
cttccCATATTAt
CTTCCCAtattat
CTTCCCAtattat
cttcCCATATTAt
cttcccATATTAT
cttcccATATTAT
ctTCCCATAttat
Created
Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
N
0.059
-0.066
-0.062
-0.042
0.154
0.154
-0.068
42831983 rs187249437 A A hsa-let-7a-3p
hsa-let-7b-3p
hsa-let-7f-1-3p
hsa-miR-300
hsa-miR-381-3p
hsa-miR-4666a-3p
hsa-miR-98-3p
2
2
2
2
2
2
2
agTTGTATAtttt
agTTGTATAtttt
agTTGTATAtttt
agTTGTATAtttt
agTTGTATAtttt
agTTGTATAtttt
agTTGTATAtttt
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
-0.008
0.011
0.001
0.03
0.03
0.023
0.011
G hsa-miR-4731-3p
hsa-miR-4801
2
2
agTTGTGTAtttt
agTTGTGTAtttt
Created
Created
N
N
-0.012
-0.019
42832472 rs201656232 - TG hsa-miR-4719
2
atgaATTTGTGtgtc
Unknown
N
0.002
-
42833058 rs116806586 A A hsa-let-7a-3p
hsa-let-7b-3p
hsa-let-7f-1-3p
hsa-miR-1284
hsa-miR-300
hsa-miR-381-3p
hsa-miR-4666a-3p
hsa-miR-7849-3p
hsa-miR-98-3p
2
2
2
2
2
2
2
2
2
aaTTGTATAgttt
aaTTGTATAgttt
aaTTGTATAgttt
aatTGTATAGttt
aaTTGTATAgttt
aaTTGTATAgttt
aATTGTATAgttt
AATTGTAtagttt
aaTTGTATAgttt
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
N
N
0.044
0.044
0.035
-0.058
0.082
0.089
0.112
0.072
-0.003
G hsa-miR-4731-3p
hsa-miR-4801
2
2
aaTTGTGTAgttt
aaTTGTGTAgttt
Created
Created
N
N
0.05
0.043
42833241 rs139700940 C C hsa-miR-4517
hsa-miR-5583-3p
1
1
agtttgCATATTA
agtttgCATATTA
Disrupted
Disrupted
N
N
0.078
0.074
T hsa-let-7a-3p
hsa-let-7b-3p
hsa-let-7f-1-3p
hsa-miR-1277-5p
hsa-miR-300
hsa-miR-381-3p
hsa-miR-4666a-3p
hsa-miR-98-3p
2
2
2
1
2
2
2
2
agtTTGTATAtta
agtTTGTATAtta
agtTTGTATAtta
agtttgTATATTA
agtTTGTATAtta
agtTTGTATAtta
agtTTGTATAtta
agtTTGTATAtta
Created
Created
Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
N
N
0.036
0.026
0.026
0.144
0.092
0.092
0.095
0.017
42833246 rs112772563 T T hsa-miR-4517
hsa-miR-5583-3p
hsa-miR-889-3p
1
1
1
gCATATTAagatt
gCATATTAagatt
gcATATTAAgatt
Disrupted
Disrupted
Disrupted
N
N
N
0.076
0.074
0.141
C hsa-miR-190a-5p
hsa-miR-190b
1
1
gCATATCAagatt
gCATATCAagatt
Created
Created
N
N
0.008
0.008
42833328 rs200513807 G G hsa-miR-197-3p
hsa-miR-412-3p
hsa-miR-6754-3p
hsa-miR-95-5p
2
1
1
2
tttatTGGTGAAg
tttattGGTGAAG
tttattGGTGAAG
TTTATTGgtgaag
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
0.013
-0.043
-0.043
0.115
T hsa-miR-4719
hsa-miR-513b-5p
2
2
tttATTTGTGAag
tttatTTGTGAAg
Created
Created
N
N
0.101
0.071
42833740 rs113190084 T
C hsa-miR-297
hsa-miR-3171
hsa-miR-567
2
3
2
gACATACAtcaaa
gacATACATCAaa
gACATACAtcaaa
Created
Created
Created
N
N
N
0.005
-0.018
0.011
42834514 rs111545137 - C hsa-miR-125b-2-3p
hsa-miR-4731-3p
hsa-miR-4801
0 attttACTTGTGt
attttaCTTGTGT
attttaCTTGTGT
Unknown
Unknown
Unknown
N
N
N
-0.154
-0.148
-0.167
T hsa-miR-3163
hsa-miR-4719
0 ATTTTATttgtgt
attttATTTGTGt
Unknown
Unknown
N
N
0.051
-0.132

Genome Browser