SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001012270
Gene Symbol: BIRC5
Description: Homo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 2, mRNA.
Gene Location: chr17(+):76210276-76221716
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr17:g.78223712->T ICGC_ssm_v3_22274 BN50T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3617 tgtttTGTCTTTgaaagtgg
 0 AAAGACAU m7a Created NA NA 0.910000
hsa-miR-548u tgttttGTCTTTGaaagtgg
 0 CAAAGACU m7a Created NA NA -1.370000
hsa-miR-641 tgtttTGTCTTTgaaagtgg
 0 AAAGACAU m7a Created NA NA 1.200000


Mutation Mutation ID Sample Name Cancer Type
chr17:g.78223775TC>- ICGC_1428649 TCGA-AP-A0LP-01A-12D-A10B-09 UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr17:g.78224056G>T ICGC_6865AF92-2A78-11E2-848B-FEFC496BB9B8 CPCG_0006_Pr_P_F0 [prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3529-3p tgTTGTTGTTtttttttgt
 0 AACAACAA m8a (m7a->m8a) -0.25 -0.292 -1.75
hsa-miR-5003-5p tgtTGTTGTGtttttttgt
 0 UCACAACA m7b (m7b->m6b) -0.262 -0.077 0.07

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78225488G>A COSN4770657 tumor_4177376 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1538 gagcccctCGGGCCaactg
 1
 CGGCCCGG m6b Disrupted -0.242000 no TS 0.010000
hsa-miR-3184-5p gaGCCCCTCAggccaactg
 1
 UGAGGGGC m8a (m7a->m8a) -0.354000 -0.584000 -2.030000
hsa-miR-328 gagcccctcGGGCCAactg
 1
 CUGGCCCU m6b Disrupted -0.185000 no TS 6.800000
hsa-miR-423-5p gaGCCCCTCAggccaactg
 1
 UGAGGGGC m8a (m7a->m8a) -0.345000 -0.572000 -0.280000
hsa-miR-4745-3p gagcccctCGGGCCAactg
 1
 UGGCCCGG m7a Disrupted -0.246000 no TS No effect
hsa-miR-544b gagccCCTCAGGccaactg
 0 ACCUGAGG m7b Created no TS -0.105000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78225600C>A COSN9323436 AOCS-057-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4424 agagTAACTCacaattgcc
 0 AGAGUUAA m6b Disrupted -0.101000 no TS 4.330000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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