| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_138627 |
|---|---|
| Gene Symbol: | BCL2L11 |
| Description: | Homo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 11, mRNA. |
| Gene Location: | chr2(+):111878490-111926022 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111164160G>A | ICGC_1302764 | TCGA-A5-A0GU-01A-11W-A062-09 | UterineCorpusEndometrioidCarcinoma(TCGA,US) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-647 |
caaGCAGCCAaagaccacc |
0 | GUGGCUGC | m7b | (m6b->m7b) | -0.184 | -0.368 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111164172C>T | ICGC_1302765 | TCGA-BS-A0UV-01A-11D-A10B-09 | UterineCorpusEndometrioidCarcinoma(TCGA,US) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3677-3p |
gaccaCCCACGAatggtta |
0 | CUCGUGGG | m7b | Disrupted | -0.576 | no TS | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111164194->A | ICGC_1302766 | TCGA-AJ-A23M-01A-11D-A159-09 | UterineCorpusEndometrioidCarcinoma(TCGA,US) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-132-3p |
tacGACTGTTAcgttacat |
0 | UAACAGUC | m8a | Disrupted | -0.292000 | -0.312000 |
0.360000 |
|
| hsa-miR-194-5p |
tacgaCTGTTACgttacat |
0 | UGUAACAG | m7b | Disrupted | -0.151000 | no TS |
0.100000 |
|
| hsa-miR-212-3p |
tacGACTGTTAcgttacat |
0 | UAACAGUC | m8a | Disrupted | -0.271000 | -0.291000 |
0.310000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111164592A>G | COSN1778139 | RK167_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111164735A>G | COSN1778140 | RK080_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4469 |
tttttaaacAGGGAGacgt |
7 |
GCUCCCUC | m6b | Disrupted | -0.269000 | -0.162000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111165062A>G | COSN1778141 | RK208_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3166 |
agagttaaTGTCTGCctgt |
2 |
CGCAGACA | m7b | Created | -0.056000 | -0.194000 |
-0.430000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111165142G>A | COSN4794401 | tumor_4160468 | [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3655 |
catttCGACAAGCatgtta |
0 | GCUUGUCG | m8a | Created | no TS | -0.136000 |
0.050000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111165679G>T | COSN14581835 | 8066067 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-130b-5p |
cccaaGAAAGAGTcaggtt |
0 | ACUCUUUC | m8a | Disrupted | 0.104000 | no TS |
0.270000 |
|
| hsa-miR-138-2-3p |
cccaaGAAATAGtcaggtt |
0 | GCUAUUUC | m7b | Created | no TS | 0.139000 |
-0.030000 |
|
| hsa-miR-345-5p |
cccaagaaaGAGTCAGgtt |
2 |
GCUGACUC | m7b | (m7b->m6c) | -0.268000 | -0.259000 |
3.420000 |
|
| hsa-miR-130b-5p |
cccaaGAAAGAGTcaggtt |
0 | ACUCUUUC | m8a | Disrupted | 0.104000 | no TS |
0.270000 |
|
| hsa-miR-138-2-3p |
cccaaGAAATAGtcaggtt |
0 | GCUAUUUC | m7b | Created | no TS | 0.139000 |
-0.030000 |
|
| hsa-miR-345-5p |
cccaagaaaGAGTCAGgtt |
2 |
GCUGACUC | m7b | (m7b->m6c) | -0.268000 | -0.259000 |
3.420000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111166776G>A | COSN8606992 | 360_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1260a |
gggGGTGGGAgttgcggag |
3 |
AUCCCACC | m7b | (m6b->m7b) | -0.377000 | -0.392000 | No effect | |
| hsa-miR-1260b |
gggGGTGGGAgttgcggag |
3 |
AUCCCACC | m7b | (m6b->m7b) | -0.377000 | -0.392000 | No effect | |
| hsa-miR-532-3p |
ggggGTGGGAGttgcggag |
0 | CCUCCCAC | m7b | Created | no TS | -0.015000 |
-1.220000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111166831A>T | COSN1778142 | RK023_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-183-3p |
tagtggAATTCAattgtct |
0 | GUGAAUUA | m6b | Created | no TS | 0.124000 | No effect | |
| hsa-miR-4452 |
tagtgGAATTCAAttgtct |
0 | UUGAAUUC | m8a | Created | no TS | 0.127000 | No effect | |
| hsa-miR-630 |
tagtgGAATACaattgtct |
0 | AGUAUUCU | m6b | Disrupted | 0.047000 | no TS |
0.080000 |
|
| hsa-miR-183-3p |
tagtggAATTCAattgtct |
0 | GUGAAUUA | m6b | Created | no TS | 0.124 | No effect | |
| hsa-miR-4452 |
tagtgGAATTCAAttgtct |
0 | UUGAAUUC | m8a | Created | no TS | 0.127 | No effect | |
| hsa-miR-630 |
tagtgGAATACaattgtct |
0 | AGUAUUCU | m6b | Disrupted | 0.047 | no TS |
0.08 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.111167717A>G | COSN6418209 | HX36T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.111168392A>C | COSN8553704 | tumor_4163639 | [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][diffuse_large_B_cell_lymphoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-320a |
taactgCAGCTTTTtaaac |
5 |
AAAAGCUG | m8a | Created | 0.003000 | -0.185000 |
-0.010000 |
| hsa-miR-320b |
taactgCAGCTTTTtaaac |
5 |
AAAAGCUG | m8a | Created | 0.003000 | -0.185000 |
-0.010000 |
| hsa-miR-320c |
taactgCAGCTTTTtaaac |
5 |
AAAAGCUG | m8a | Created | 0.003000 | -0.185000 |
-0.010000 |
| hsa-miR-320d |
taactgCAGCTTTTtaaac |
5 |
AAAAGCUG | m8a | Created | 0.003000 | -0.185000 | No effect |
| hsa-miR-4429 |
taactgCAGCTTTTtaaac |
5 |
AAAAGCUG | m8a | Created | 0.003000 | -0.176000 | No effect |
| hsa-miR-548c-3p |
taactgcaGATTTTTaaac |
0 | CAAAAAUC | m7b | Disrupted | 0.822000 | 0.935000 |
0.160000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 111164173 | rs185078669 | G | G |
hsa-miR-3677-3p |
1 |
aCCCACGAAtggt |
Disrupted |
N |
-0.576 |
| A |
hsa-miR-4265 hsa-miR-4296 hsa-miR-4322 hsa-miR-6748-5p hsa-miR-6759-5p hsa-miR-6793-5p hsa-miR-6796-5p |
1 1 1 1 1 1 1 |
aCCCACAAatggt aCCCACAAatggt aCCCACAAatggt ACCCACAaatggt ACCCACAAatggt ACCCACAaatggt aCCCACAAatggt |
Created Created Created Created Created Created Created |
N N N N N N N |
-0.187 -0.187 -0.184 -0.22 -0.384 -0.185 -0.179 |
|||
| 111164197 | rs150291943 | G | G |
hsa-miR-379-3p hsa-miR-411-3p |
12 12 |
tgttacGTTACAT tgttacGTTACAT |
Disrupted Disrupted |
N N |
0.067 0.067 |
| A |
hsa-miR-194-5p hsa-miR-380-3p |
11 12 |
TGTTACAttacat tgttacATTACAT |
Created Created |
N N |
-0.161 -0.04 |
|||
| 111164456 | rs115158848 | G | G |
hsa-miR-4469 hsa-miR-7106-3p |
8 2 |
GAGGGAGcattct gAGGGAGCAttct |
Disrupted Disrupted |
N N |
-0.213 -0.415 |
| A |
hsa-miR-642a-5p hsa-miR-642b-5p |
8 2 |
GAGGGAAcattct gAGGGAACAttct |
Created Created |
N N |
-0.174 -0.358 |
|||
| 111165561 | rs112485457 | C | C |
hsa-miR-3652 hsa-miR-4430 hsa-miR-4505 hsa-miR-4731-5p hsa-miR-5787 hsa-miR-615-5p hsa-miR-6842-3p hsa-miR-7155-5p hsa-miR-7704 |
1 1 1 2 1 1 1 1 1 |
gtgaccCCAGCCA gtgaccCCAGCCA gtgacCCCAGCCA gtgaCCCCAGCca gtgacCCCAGCCA gtGACCCCAgcca gtgaccCCAGCCA gtgACCCCAGcca gtGACCCCAgcca |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N |
-0.013 -0.01 -0.083 -0.075 -0.073 -0.039 0.026 -0.012 -0.046 |
| G |
hsa-miR-604 hsa-miR-647 hsa-miR-6762-3p |
1 1 1 |
gtgacCGCAGCCA gtgaccGCAGCCA gtgaccGCAGCCA |
Created Created Created |
N N N |
-0.137 -0.023 -0.041 |
|||
| 111165771 | rs13422314 | A | A |
hsa-miR-382-5p hsa-miR-548az-5p hsa-miR-548n hsa-miR-548t-5p |
1 1 1 1 |
taaACAACTTtta taaacaACTTTTA taaacaACTTTTA taaacaACTTTTA |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.065 0.124 0.123 0.124 |
| G |
hsa-miR-320a hsa-miR-320b hsa-miR-320c hsa-miR-320d hsa-miR-4429 hsa-miR-548e-5p |
1 1 1 1 1 1 |
taaaCAGCTTTta taaaCAGCTTTta taaaCAGCTTTta taaaCAGCTTTta taaaCAGCTTTta taaacaGCTTTTA |
Created Created Created Created Created Created |
N N N N N N |
-0.052 -0.052 -0.052 -0.052 -0.052 0.087 |
|||
| 111166121 | rs180695314 | A | A |
hsa-miR-1255b-2-3p |
1 |
AGTGGTAggattg |
Disrupted |
N |
0.039 |
| G |
hsa-miR-1224-3p hsa-miR-1260a hsa-miR-1260b |
2 2 2 |
agtGGTGGGAttg agtGGTGGGAttg agtGGTGGGAttg |
Created Created Created |
N N N |
-0.003 -0.032 -0.041 |
|||
| 111167628 | rs76256675 | G | G |
hsa-miR-1224-3p hsa-miR-1260a hsa-miR-1260b hsa-miR-4433-5p hsa-miR-4433b-5p hsa-miR-6748-3p |
3 3 3 3 3 4 |
gGGTGGGAcaggt gGGTGGGAcaggt gGGTGGGAcaggt ggGTGGGACAggt gggTGGGACAggt gggtgGGACAGGt |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N |
-0.085 -0.091 -0.091 -0.211 -0.049 -0.053 |
| A |
hsa-miR-1266-3p |
4 |
gggtgGAACAGGt |
Created |
N |
-0.027 |