SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_001204108
Gene Symbol:	BCL2L11
Description:	Homo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 11, mRNA.
Gene Location:	chr2(+):111878490-111926022
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.111161466T>C			ICGC_ssm_v3_94998		HCC3T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-145-5p	gcagacttACTGGACacta	0	GUCCAGUU	m7a	Created	NA	NA	No effect
hsa-miR-198	gcagacttaCTGGACacta	0	GGUCCAGA	m6b	Created	-0.057	-0.198	-0.01
hsa-miR-323b-3p	gcagactTATTGGacacta	0	CCCAAUAC	m6b	Disrupted	-0.063	no TS	0.06

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.111164160G>A			ICGC_1302764		TCGA-A5-A0GU-01A-11W-A062-09		UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-647	caaGCAGCCAaagaccacc	0	GUGGCUGC	m7b	(m6b->m7b)	-0.166	-0.645	-0.73

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.111164172C>T			ICGC_1302765		TCGA-BS-A0UV-01A-11D-A10B-09		UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3677-3p	gaccaCCCACGAatggtta	0	CUCGUGGG	m7b	Disrupted	-0.551	no TS	0.01

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.111164194->A			ICGC_1302766		TCGA-AJ-A23M-01A-11D-A159-09		UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-132-3p	tacGACTGTTAcgttacat	0	UAACAGUC	m8a	Disrupted	-0.260000	-0.280000	0.630000
hsa-miR-194-5p	tacgaCTGTTACgttacat	0	UGUAACAG	m7b	Disrupted	-0.133000	no TS	0.660000
hsa-miR-212-3p	tacGACTGTTAcgttacat	0	UAACAGUC	m8a	Disrupted	-0.239000	-0.259000	0.560000

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.111166831A>T			ICGC_sm102534		RK023_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-183-3p	tagtggAATTCAattgtct	0	GUGAAUUA	m6b	Created	no TS	0.124	No effect
hsa-miR-4452	tagtgGAATTCAAttgtct	0	UUGAAUUC	m8a	Created	no TS	0.127	No effect
hsa-miR-630	tagtgGAATACaattgtct	0	AGUAUUCU	m6b	Disrupted	0.047	no TS	0.07

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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