SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_206866
Gene Symbol: BACH1
Description: Homo sapiens BTB and CNC homology 1, basic leucine zipper transcription factor 1 (BACH1), transcript variant 2, mRNA.
Gene Location: chr21(+):30671736-30718469
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr21:g.29343586C>T COSN8565244 tumor_4163639 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][diffuse_large_B_cell_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3121-3p catggacttTCTATTTcct
 15
 UAAAUAGA m7b (m6c->m7b) -0.095000 -0.044000 No effect
hsa-miR-4476 catggaCTTCCTatttcct
 1
 CAGGAAGG m6b Disrupted -0.023000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr21:g.29343971C>T COSN5984562 RK162_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1253 tgctcTCTTCTCcaaattt
 10
 AGAGAAGA m7b Disrupted -0.049000 -0.065000 2.950000
hsa-miR-1270 tgctctctTCTCCAaattt
 1
 CUGGAGAU m6b Disrupted -0.036000 no TS 0.360000
hsa-miR-3148 tgctctcTTTTCCAaattt
 0 UGGAAAAA m7a Created -0.019000 0.066000 No effect
hsa-miR-3978 tgctctctTTTCCAaattt
 0 GUGGAAAG m6b Created no TS 0.049000 -0.040000
hsa-miR-4311 tgcTCTCTTTtccaaattt
 0 GAAAGAGA m7b (m6b->m7b) no TS 0.082000 -0.440000
hsa-miR-4434 tgctctCTTCTCCaaattt
 7
 AGGAGAAG m7b Disrupted -0.191000 -0.093000 0.030000
hsa-miR-4516 tgctctCTTCTCCaaattt
 7
 GGGAGAAG m7b Disrupted -0.156000 -0.058000 1.500000
hsa-miR-4531 tgctctcTTCTCCAaattt
 7
 AUGGAGAA m7b Disrupted -0.135000 -0.110000 0.010000
hsa-miR-5197-3p tgctCTCTTCTccaaattt
 1
 AAGAAGAG m7b Disrupted 0.011000 no TS 0.100000
hsa-miR-5703 tgctctCTTCTCCaaattt
 7
 AGGAGAAG m7b Disrupted -0.211000 -0.081000 0.120000
hsa-miR-620 tgctctctTCTCCAaattt
 1
 AUGGAGAU m6b Disrupted -0.029000 no TS 0.030000

Mutation Mutation ID Sample Name Cancer Type
chr21:g.29344660G>A COSN7143246 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3941 tgtGTGTGTAtgtgtgtgt
 0 UUACACAC m7b (m6b->m7b) 0.042000 0.075000 0.130000
hsa-miR-4789-3p tgtgtgtgTATGTGTGtgt
 1
 CACACAUA m8a Created 0.149000 0.254000 0.400000

Mutation Mutation ID Sample Name Cancer Type
chr21:g.29344666G>A COSN7143247 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-329 tgtgtgtGTGTGTatgtgt
 0 AACACACC m6b Disrupted 0.037000 0.034000 0.150000
hsa-miR-362-3p tgtgtgtGTGTGTatgtgt
 0 AACACACC m6b Disrupted 0.037000 0.034000 0.100000
hsa-miR-3941 tgtgtgtGTGTGTAtgtgt
 0 UUACACAC m7b Disrupted 0.042000 0.035000 0.200000

Mutation Mutation ID Sample Name Cancer Type
chr21:g.29345005C>A COSN10025188 C0059T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-452-5p acctatAAACAGTTtagca
 0 AACUGUUU m8a Disrupted -0.056000 no TS 2.450000
hsa-miR-4676-3p acctatAAACAGTttagca
 0 CACUGUUU m7b Disrupted -0.010000 no TS 0.110000
hsa-miR-548av-3p acctataaaCAGTTTagca
 10
 AAAACUGC m6b Disrupted 0.043000 no TS 0.020000
hsa-miR-548g-3p acctataaACAGTTTagca
 3
 AAAACUGU m7b Disrupted -0.100000 -0.097000 0.600000

Mutation Mutation ID Sample Name Cancer Type
chr21:g.29345931A>G COSN8611632 J46_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3617 tttttttATGTCTTTcata
 2
 AAAGACAU m8a Created 0.136000 -0.083000 -0.370000
hsa-miR-641 tttttttATGTCTTTcata
 2
 AAAGACAU m8a Created 0.117000 -0.083000 -1.400000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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