| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_005603 |
|---|---|
| Gene Symbol: | ATP8B1 |
| Description: | Homo sapiens ATPase, aminophospholipid transporter, class I, type 8B, member 1 (ATP8B1), mRNA. |
| Gene Location: | chr18(-):55313658-55470327 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr18:g.57646529T>C | COSN6128612 | RK308_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-2355-3p |
ttctttGGACAAattattt |
0 | AUUGUCCU | m6b | Created | no TS | -0.200000 |
-0.030000 |
|
| hsa-miR-32-3p |
ttctttggaTAAATTattt |
2 |
CAAUUUAG | m6b | Disrupted | 0.097000 | 0.084000 | No effect | |
| hsa-miR-4646-3p |
ttctttGGACAAattattt |
0 | AUUGUCCC | m6b | Created | no TS | -0.194000 |
-1.540000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr18:g.57647612A>C | COSN5846966 | HX25T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-374a-5p |
tgTATTATAAaattacagt |
0 | UUAUAAUA | m8a | (m8a->m7b) | 0.076000 | 0.064000 |
0.050000 |
|
| hsa-miR-4775 |
tgtattatAAAATTAcagt |
2 |
UUAAUUUU | m7b | Disrupted | 0.376000 | 0.284000 | No effect | |
| hsa-miR-568 |
tgtaTTATACAattacagt |
0 | AUGUAUAA | m7b | Created | no TS | -0.107000 |
-0.220000 |
|
| hsa-miR-590-3p |
tgtattaTAAAATTAcagt |
2 |
UAAUUUUA | m8a | Disrupted | 0.492000 | 0.353000 |
0.280000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr18:g.57647754A>T | COSN7364016 | 8047810 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4282 |
tcaaaaaAAATTTTttaat |
0 | UAAAAUUU | m7b | Disrupted | 0.078000 | 0.082000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr18:g.57647822C>G | ICGC_8DACB804-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4418 |
gtggaggtTGCAGTGagcc |
0 | CACUGCAG | m7a | Created | NA | NA |
2.53 |
|
| hsa-miR-4772-3p |
gtggagGTTGCAGtgagcc |
0 | CCUGCAAC | m7b | Created | -0.102 | -0.138 |
-0.15 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr18:g.57647902C>T | ICGC_C9B23464-2A78-11E2-BDED-1EFD496BB9B8 | CPCG_0103_Pr_P_P4 | ProstateCancer(OICR,CA) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4435 |
agaccagcCTGGCCAacat |
0 | AUGGCCAG | m7b | Created | no TS | -0.219 |
-0.91 |
|
| hsa-miR-4492 |
agaCCAGCCCggccaacat |
0 | GGGGCUGG | m7b | (m7b->m6c) | -0.501 | -0.373 | No effect | |
| hsa-miR-4498 |
agaCCAGCCCggccaacat |
0 | UGGGCUGG | m7b | (m7b->m6c) | -0.501 | -0.373 | No effect | |
| hsa-miR-4743 |
agaccagcCCGGCCAacat |
0 | UGGCCGGA | m7a | Disrupted | -0.218 | no TS |
0.01 |
|
| hsa-miR-4755-3p |
agaccaGCCTGGCcaacat |
0 | AGCCAGGC | m7b | Created | no TS | -0.159 |
-0.01 |
|
| hsa-miR-5001-5p |
agaCCAGCCCggccaacat |
0 | AGGGCUGG | m7b | (m7b->m6c) | -0.491 | -0.363 | No effect | |
| hsa-miR-548s |
agaccagccTGGCCAacat |
0 | AUGGCCAA | m6b | Created | no TS | -0.073 | No effect | |
| hsa-miR-762 |
agaCCAGCCCggccaacat |
0 | GGGGCUGG | m7b | (m7b->m6c) | -0.482 | -0.363 |
0.27 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr18:g.57647955T>C | ICGC_8DACBDFE-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1255a |
ctgTCATCCTagcactttg |
0 | AGGAUGAG | m7a | (m7a->m6b) | NA | NA | No effect |
| hsa-miR-1265 |
ctgtCATCCTagcactttg |
0 | CAGGAUGU | m6b | Disrupted | -0.035 | no TS |
0.05 |
| hsa-miR-204-3p |
ctgtcaTCCCAGCactttg |
0 | GCUGGGAA | m7a | Created | -0.123 | -0.123 | No effect |
| hsa-miR-512-3p |
ctgtcatccCAGCACTTtg |
0 | AAGUGCUG | m8a | (m7a->m8a) | -0.119 | -0.169 | No effect |
| hsa-miR-5187-5p |
ctgTCATCCCAgcactttg |
0 | UGGGAUGA | m8a | Created | no TS | -0.211 | No effect |
| hsa-miR-5589-5p |
ctgtcatCCCAGCactttg |
0 | GGCUGGGU | m6b | Created | -0.145 | -0.242 | No effect |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 57646548 | rs117693241 | A | A |
hsa-miR-4282 |
6 |
AATTTTAaatgca |
Disrupted |
N |
0.048 |
| G |
hsa-miR-4698 hsa-miR-8063 |
6 6 |
aATTTTGAatgca aATTTTGAatgca |
Created Created |
N N |
0.01 0.007 |
|||
| 57646551 | rs1129621 | T | T |
hsa-miR-4282 |
6 |
aacAATTTTAaat |
Disrupted |
N |
0.048 |
| A |
hsa-miR-889-3p |
6 |
aacaATATTAAat |
Created |
N |
-0.004 |
|||
| 57647901 | rs317822 | G | G |
hsa-miR-4743-5p |
1 |
cagcCCGGCCAac |
Disrupted |
N |
-0.218 |
| A |
hsa-miR-1587 hsa-miR-3620-5p hsa-miR-3652 hsa-miR-378g hsa-miR-4430 hsa-miR-4492 hsa-miR-4498 hsa-miR-4505 hsa-miR-4656 hsa-miR-4675 hsa-miR-4741 hsa-miR-5001-5p hsa-miR-5787 hsa-miR-647 hsa-miR-6829-5p hsa-miR-6842-3p hsa-miR-762 |
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 |
CAGCCCAgccaac CAGCCCAgccaac cagcCCAGCCAac cAGCCCAGccaac cagcCCAGCCAac CAGCCCAgccaac CAGCCCAgccaac cagCCCAGCCAac CAGCCCAgccaac CAGCCCAgccaac CAGCCCAgccaac CAGCCCAgccaac cagCCCAGCCAac cagccCAGCCAAc CAGCCCAgccaac cagcCCAGCCAAc CAGCCCAgccaac |
Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created |
N N N N N N N N N N N N N N N N N |
-0.087 -0.096 -0.099 -0.087 -0.095 -0.167 -0.167 -0.287 -0.107 -0.126 -0.102 -0.167 -0.287 -0.078 -0.098 -0.254 -0.165 |