SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000053
Gene Symbol: ATP7B
Description: Homo sapiens ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1, mRNA.
Gene Location: chr13(-):52506805-52585630

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr13:g.51932974C>G COSN6627185 CHC433T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3198 cagccccccGACTCCAgcc
 0 GUGGAGUC m7b (m6b->m7b) no TS -0.070000 -3.760000
hsa-miR-4294 cagccccccGACTCCagcc
 0 GGGAGUCU m6b Created no TS -0.080000 -2.350000
hsa-miR-4309 cagccccccGACTCCAGcc
 0 CUGGAGUC m8a (m7a->m8a) no TS -0.033000 -0.540000
hsa-miR-4447 cagccCCCCCACtccagcc
 2
 GGUGGGGG m7b Disrupted -0.154000 no TS 6.630000
hsa-miR-4472 cagccCCCCCACtccagcc
 2
 GGUGGGGG m7b Disrupted -0.154000 no TS 3.630000
hsa-miR-4481 cagccccCCCACTCCagcc
 1
 GGAGUGGG m8a Disrupted -0.198000 -0.096000 5.920000
hsa-miR-4745-5p cagccccCCCACTCcagcc
 1
 UGAGUGGG m7b Disrupted -0.180000 -0.096000 2.060000
hsa-miR-4785 cagccccCCGACTCcagcc
 0 AGAGUCGG m7b Created no TS -0.179000 -12.710000
hsa-miR-4787-5p cagcCCCCCGactccagcc
 0 GCGGGGGU m6b Created no TS -0.226000 -3.630000

Mutation Mutation ID Sample Name Cancer Type
chr13:g.51932983C>T COSN8594369 AOCS-139-12-5 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-185-3p ccttgttttCAGCCCCccc
 2
 AGGGGCUG m7b (m7b->m6b) -0.187000 no TS No effect
hsa-miR-4489 ccttgttttTAGCCCCccc
 0 UGGGGCUA m7b (m6b->m7b) no TS -0.219000 0.030000
hsa-miR-4656 ccttgtttTCAGCCCcccc
 2
 UGGGCUGA m7b Disrupted -0.219000 no TS 0.510000
hsa-miR-548ac ccttGTTTTTagccccccc
 0 CAAAAACC m6b Created no TS 0.108000 -0.240000
hsa-miR-548ae ccttGTTTTTagccccccc
 0 CAAAAACU m6b Created -0.078000 0.030000 0.310000
hsa-miR-548ah-3p ccttGTTTTTagccccccc
 0 CAAAAACU m6b Created -0.078000 0.030000 0.110000
hsa-miR-548am-3p ccttGTTTTTagccccccc
 0 CAAAAACU m6b Created -0.078000 0.030000 0.300000
hsa-miR-548aq-3p ccttGTTTTTagccccccc
 0 CAAAAACU m6b Created -0.078000 0.030000 0.040000
hsa-miR-548d-3p ccttGTTTTTagccccccc
 0 CAAAAACC m6b Created no TS 0.112000 0.190000
hsa-miR-548h-3p ccttGTTTTTagccccccc
 0 CAAAAACC m6b Created no TS 0.105000 -4.690000
hsa-miR-548z ccttGTTTTTagccccccc
 0 CAAAAACC m6b Created no TS 0.105000 -4.690000
hsa-miR-570-3p cctTGTTTTCagccccccc
 2
 CGAAAACA m7b (m7b->m6c) -0.003000 0.022000 0.450000
hsa-miR-644b-5p ccttgtttTTAGCCCcccc
 0 UGGGCUAA m7b Created no TS -0.174000 -1.330000

Mutation Mutation ID Sample Name Cancer Type
chr13:g.51933012C>T COSN6627186 CHC433T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3614-5p aaatCCAAGTGcgctgttg
 0 CCACUUGG m7b Created no TS -0.192000 -2.880000
hsa-miR-890 aaaTCCAAGTgcgctgttg
 0 UACUUGGA m7b (m6c->m7b) no TS -0.177000 -1.604000

Mutation Mutation ID Sample Name Cancer Type
chr13:g.51933156G>A COSN1611980 RK025_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3180-5p ttgcctcCTGGAAGaacaa
 0 CUUCCAGA m7a Disrupted NA NA No effect
hsa-miR-4266 ttgCCTCCTAGaagaacaa
 0 CUAGGAGG m8a Created no TS -0.158000 -2.280000
hsa-miR-4459 ttgCCTCCTGGaagaacaa
 3
 CCAGGAGG m8a Disrupted -0.163000 no TS No effect
hsa-miR-4659a-3p ttgcctcctAGAAGAAcaa
 0 UUUCUUCU m7b (m6b->m7b) no TS -0.046000 -1.820000
hsa-miR-4659b-3p ttgcctcctAGAAGAAcaa
 0 UUUCUUCU m7b (m6b->m7b) no TS -0.036000 -0.480000
hsa-miR-4695-5p ttGCCTCCTGgaagaacaa
 3
 CAGGAGGC m8a (m8a->m7b) -0.193000 -0.366000 -0.090000
hsa-miR-4768-3p ttgcCTCCTGGaagaacaa
 1
 CCAGGAGA m7a Disrupted -0.083000 -0.083000 No effect
hsa-miR-665 ttgcCTCCTGGaagaacaa
 4
 ACCAGGAG m7b Disrupted -0.285000 no TS 0.250000
hsa-miR-3180-5p ttgcctcCTGGAAGaacaa
 0 CUUCCAGA m7a Disrupted NA NA No effect
hsa-miR-4266 ttgCCTCCTAGaagaacaa
 0 CUAGGAGG m8a Created no TS -0.158000 -2.280000
hsa-miR-4459 ttgCCTCCTGGaagaacaa
 3
 CCAGGAGG m8a Disrupted -0.163000 no TS No effect
hsa-miR-4659a-3p ttgcctcctAGAAGAAcaa
 0 UUUCUUCU m7b (m6b->m7b) no TS -0.046000 -1.820000
hsa-miR-4659b-3p ttgcctcctAGAAGAAcaa
 0 UUUCUUCU m7b (m6b->m7b) no TS -0.036000 -0.480000
hsa-miR-4695-5p ttGCCTCCTGgaagaacaa
 3
 CAGGAGGC m8a (m8a->m7b) -0.193000 -0.366000 -0.090000
hsa-miR-4768-3p ttgcCTCCTGGaagaacaa
 1
 CCAGGAGA m7a Disrupted -0.083000 -0.083000 No effect
hsa-miR-665 ttgcCTCCTGGaagaacaa
 4
 ACCAGGAG m7b Disrupted -0.285000 no TS 0.250000
hsa-miR-3180-5p ttgcctcCTGGAAGaacaa
 0 CUUCCAGA m7a Disrupted NA NA No effect
hsa-miR-4266 ttgCCTCCTAGaagaacaa
 0 CUAGGAGG m8a Created no TS -0.158 -2.28
hsa-miR-4459 ttgCCTCCTGGaagaacaa
 0 CCAGGAGG m8a Disrupted -0.163 no TS No effect
hsa-miR-4659a-3p ttgcctcctAGAAGAAcaa
 0 UUUCUUCU m7b (m6b->m7b) no TS -0.046 -1.82
hsa-miR-4659b-3p ttgcctcctAGAAGAAcaa
 0 UUUCUUCU m7b (m6b->m7b) no TS -0.036 -0.48
hsa-miR-4695-5p ttGCCTCCTGgaagaacaa
 0 CAGGAGGC m8a (m8a->m7b) -0.193 -0.366 -0.09
hsa-miR-4768-3p ttgcCTCCTGGaagaacaa
 0 CCAGGAGA m7a Disrupted -0.083 -0.083 No effect
hsa-miR-665 ttgcCTCCTGGaagaacaa
 0 ACCAGGAG m7b Disrupted -0.285 no TS 0.25

Mutation Mutation ID Sample Name Cancer Type
chr13:g.51933584G>A COSN6627187 CHC322T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-30a-5p ggagcatcTGTTTACctgg
 2
 UGUAAACA m7b Disrupted 0.101000 no TS 0.010000
hsa-miR-30b-5p ggagcatcTGTTTACctgg
 2
 UGUAAACA m7b Disrupted 0.110000 no TS 0.020000
hsa-miR-30c-5p ggagcatcTGTTTACctgg
 2
 UGUAAACA m7b Disrupted 0.110000 no TS 0.010000
hsa-miR-30d-5p ggagcatcTGTTTACctgg
 2
 UGUAAACA m7b Disrupted 0.110000 no TS 0.090000
hsa-miR-30e-5p ggagcatcTGTTTACctgg
 2
 UGUAAACA m7b Disrupted 0.101000 no TS 0.220000
hsa-miR-3121-3p ggagcaTCTATTTAcctgg
 0 UAAAUAGA m8a Created no TS 0.167000 No effect
hsa-miR-5683 ggagCATCTGTttacctgg
 2
 UACAGAUG m7b Disrupted 0.012000 no TS 3.080000

Mutation Mutation ID Sample Name Cancer Type
chr13:g.51934127G>A COSN7404141 8048316 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1271-3p ctctCAGGCACTtctccaa
 0 AGUGCCUG m8a Created no TS -0.164000 -0.010000
hsa-miR-33b-3p ctctcAGGCACTtctccaa
 0 CAGUGCCU m7b Created no TS -0.132000 -0.450000
hsa-miR-515-3p ctctcAGGCACTtctccaa
 0 GAGUGCCU m7b Created no TS -0.104000 No effect
hsa-miR-519e-3p ctctcAGGCACTTctccaa
 0 AAGUGCCU m8a Created no TS -0.113000 -0.360000
hsa-miR-550a-3-5p ctctCAGGCACTtctccaa
 0 AGUGCCUG m8a Created no TS -0.174000 -0.220000
hsa-miR-550a-5p ctctCAGGCACTtctccaa
 0 AGUGCCUG m8a Created no TS -0.174000 -0.220000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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