| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_025153 |
|---|---|
| Gene Symbol: | ATP10B |
| Description: | Homo sapiens ATPase, class V, type 10B (ATP10B), mRNA. |
| Gene Location: | chr5(-):159990126-160279219 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr5:g.160563141G>T | COSN7904935 | 8051900 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3148 |
ataaacatgTTTTTCCAta |
4 |
UGGAAAAA | m8a | (m7a->m8a) | -0.028000 | -0.167000 |
-0.010000 |
|
| hsa-miR-4716-5p |
ataAACATGGttttccata |
4 |
UCCAUGUU | m7b | (m7b->m6c) | -0.253000 | no TS |
0.030000 |
|
| hsa-miR-548aa |
ataaacaTGGTTTTccata |
8 |
AAAAACCA | m7b | Disrupted | -0.134000 | no TS |
0.230000 |
|
| hsa-miR-548ap-3p |
ataaacaTGGTTTTccata |
8 |
AAAAACCA | m7b | Disrupted | -0.134000 | no TS |
0.780000 |
|
| hsa-miR-548t-3p |
ataaacaTGGTTTTccata |
8 |
AAAAACCA | m7b | Disrupted | -0.134000 | no TS |
0.230000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr5:g.160563142G>T | COSN7904936 | 8051900 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-33a-3p |
aatAAACATTGttttccat |
2 |
CAAUGUUU | m8a | Created | 0.068000 | -0.045000 |
-0.420000 |
|
| hsa-miR-4716-5p |
aataAACATGGttttccat |
4 |
UCCAUGUU | m7b | Disrupted | -0.253000 | no TS |
0.040000 |
|
| hsa-miR-548aa |
aataaacaTGGTTTTccat |
8 |
AAAAACCA | m7b | Disrupted | -0.134000 | no TS |
0.230000 |
|
| hsa-miR-548ap-3p |
aataaacaTGGTTTTccat |
8 |
AAAAACCA | m7b | Disrupted | -0.134000 | no TS |
0.780000 |
|
| hsa-miR-548t-3p |
aataaacaTGGTTTTccat |
8 |
AAAAACCA | m7b | Disrupted | -0.134000 | no TS |
0.230000 |
|
| hsa-miR-570-3p |
aataaacatTGTTTTCcat |
0 | CGAAAACA | m7b | (m6b->m7b) | no TS | -0.161000 |
-2.240000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr5:g.160563401C>T | COSN9414961 | AOCS-112-1-2 | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1302 |
aggaccaacTGTCCCAgtt |
6 |
UUGGGACA | m7b | (m6b->m7b) | -0.310000 | -0.479000 | No effect | |
| hsa-miR-4298 |
aggaccaacTGTCCCAGtt |
6 |
CUGGGACA | m8a | (m7a->m8a) | -0.276000 | -0.445000 |
-0.480000 |
|
| hsa-miR-92b-5p |
aggaccaaCCGTCCCagtt |
2 |
AGGGACGG | m7b | Disrupted | -0.560000 | no TS |
0.420000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr5:g.160563976C>A | 13_13 | SJMB004_D | Medulloblastoma | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1291 |
ctggaAGGGCCAtttgcag |
0 | UGGCCCUG | m7a | Disrupted | -0.104 | no TS |
6.64 |
|
| hsa-miR-328 |
ctggaAGGGCCAtttgcag |
0 | CUGGCCCU | m7b | Disrupted | -0.162 | no TS |
6.4 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr5:g.160564583G>C | COSN5593926 | RK104_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1200 |
aaaTCAGGAGatataagca |
3 |
CUCCUGAG | m7a | (m7a->m6b) | -0.329000 | -0.329000 |
0.010000 |
|
| hsa-miR-1976 |
aaatCAGGAGatataagca |
5 |
CCUCCUGC | m6b | Disrupted | -0.114000 | -0.050000 |
1.930000 |
|
| hsa-miR-378a-5p |
aaaTCAGGAGatataagca |
0 | CUCCUGAC | m7a | (m7a->m6b) | NA | NA | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr5:g.160564799G>A | COSN5593927 | RK038_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4704-5p |
acagCTAGTGTaagaggca |
0 | GACACUAG | m7b | Disrupted | -0.222000 | no TS |
2.110000 |
|
| hsa-miR-600 |
acagctagTGTAAGaggca |
4 |
ACUUACAG | m6b | Disrupted | -0.056000 | -0.057000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr5:g.160565180C>T | COSN5071557 | HX34T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1537 |
ttctcaaatCGGTTTagac |
1 |
AAAACCGU | m6b | Disrupted | -0.163000 | no TS |
0.170000 |
|
| hsa-miR-497-3p |
ttctcaaatTGGTTTagac |
0 | CAAACCAC | m6b | Created | no TS | -0.048000 |
-0.020000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr5:g.160565286A>C | COSN6870560 | RK308_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-5010-3p |
tctgACACAAAgacgggaa |
2 |
UUUUGUGU | m7b | Disrupted | 0.001000 | no TS |
1.710000 |
|
| hsa-miR-592 |
tcTGACACAAagacgggaa |
2 |
UUGUGUCA | m8a | (m8a->m7b) | -0.277000 | -0.114000 | No effect | |
| hsa-miR-599 |
tctGACACAAagacgggaa |
2 |
GUUGUGUC | m7b | (m7b->m6c) | -0.199000 | no TS |
0.050000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr5:g.160565354G>T | COSN5071558 | HCC172 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-183-5p |
aatGTGCCATtcttattct |
6 |
UAUGGCAC | m7b | (m6c->m7b) | -0.321000 | -0.591000 | No effect | |
| hsa-miR-4432 |
aatgtgccAGTCTTattct |
2 |
AAAGACUC | m6b | Disrupted | -0.115000 | -0.020000 | No effect | |
| hsa-miR-4463 |
aatgtgCCAGTCTtattct |
5 |
GAGACUGG | m7b | Disrupted | -0.223000 | no TS |
0.660000 |
|
| hsa-miR-4499 |
aatgtgcCAGTCTTattct |
0 | AAGACUGA | m7a | Disrupted | NA | NA |
0.400000 |
|
| hsa-miR-499a-5p |
aatgtgccAGTCTTAttct |
4 |
UUAAGACU | m7b | Disrupted | -0.132000 | no TS | No effect | |
| hsa-miR-5197-5p |
aatgTGCCATTcttattct |
0 | CAAUGGCA | m7b | Created | no TS | -0.189000 |
-0.280000 |
|
| hsa-miR-183-5p |
aatGTGCCATtcttattct |
6 |
UAUGGCAC | m7b | (m6c->m7b) | -0.321000 | -0.591000 | No effect | |
| hsa-miR-4432 |
aatgtgccAGTCTTattct |
2 |
AAAGACUC | m6b | Disrupted | -0.115000 | -0.020000 | No effect | |
| hsa-miR-4463 |
aatgtgCCAGTCTtattct |
5 |
GAGACUGG | m7b | Disrupted | -0.223000 | no TS |
0.660000 |
|
| hsa-miR-4499 |
aatgtgcCAGTCTTattct |
0 | AAGACUGA | m7a | Disrupted | NA | NA |
0.400000 |
|
| hsa-miR-499a-5p |
aatgtgccAGTCTTAttct |
4 |
UUAAGACU | m7b | Disrupted | -0.132000 | no TS | No effect | |
| hsa-miR-5197-5p |
aatgTGCCATTcttattct |
0 | CAAUGGCA | m7b | Created | no TS | -0.189000 |
-0.280000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr5:g.160565357C>T | COSN7904937 | 8051974 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-4463 |
aacaatgtgCCAGTCTtat |
5 |
GAGACUGG | m7b | (m7b->m6b) | -0.223000 | no TS |
0.800000 |
| hsa-miR-4499 |
aacaatgtgTCAGTCTTat |
0 | AAGACUGA | m8a | (m7a->m8a) | no TS | -0.173000 |
-2.790000 |
| hsa-miR-4513 |
aacaatgtGTCAGTCTtat |
0 | AGACUGAC | m8a | Created | no TS | -0.278000 | No effect |
| hsa-miR-4643 |
aacaATGTGTCagtcttat |
0 | GACACAUG | m7a | Created | NA | NA | No effect |
| hsa-miR-642a-3p |
aacaATGTGTCagtcttat |
0 | AGACACAU | m7b | Created | no TS | -0.316000 |
-0.140000 |
| hsa-miR-642b-3p |
aacaATGTGTCagtcttat |
0 | AGACACAU | m7b | Created | no TS | -0.316000 |
-0.420000 |
| hsa-miR-888-3p |
aacaatgTGTCAGTCttat |
0 | GACUGACA | m8a | Created | no TS | -0.220000 |
-5.220000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 160563134 | rs11959870 | A | A |
hsa-miR-3148 hsa-miR-3688-3p hsa-miR-6124 |
4 4 4 |
TTTTCCAtagttg tTTTCCATAgttg TTTTCCAtagttg |
Disrupted Disrupted Disrupted |
N N N |
-0.048 -0.242 -0.04 |
| 160563272 | rs1053467 | C | C |
hsa-miR-183-5p hsa-miR-4426 hsa-miR-4647 hsa-miR-4662b |
6 7 7 7 |
aatGTGCCATctt aatgtgCCATCTT aatgtgCCATCTT aatgtgCCATCTT |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.248 -0.198 -0.198 -0.234 |
| T |
hsa-miR-425-5p hsa-miR-642a-3p hsa-miR-642b-3p |
6 5 5 |
aatGTGTCATctt aATGTGTCAtctt aATGTGTCAtctt |
Created Created Created |
N N N |
-0.191 -0.321 -0.321 |
|||
| 160563400 | rs141992948 | G | G |
hsa-miR-92b-5p |
2 |
ccaaCCGTCCCAg |
Disrupted |
N |
-0.56 |
| A |
hsa-miR-1193 hsa-miR-5187-5p hsa-miR-619-5p hsa-miR-6506-5p hsa-miR-6728-5p hsa-miR-758-5p hsa-miR-8069 hsa-miR-92a-1-5p |
2 2 2 2 2 2 2 2 |
ccaACCATCCcag ccaacCATCCCAg ccaaccATCCCAG ccaaccATCCCAG ccaacCATCCCAg cCAACCATcccag ccAACCATCccag CCAACCAtcccag |
Created Created Created Created Created Created Created Created |
N N N N N N N N |
-0.18 -0.139 -0.121 -0.121 -0.157 -0.093 -0.062 -0.116 |
|||
| 160563401 | rs191433217 | C | C |
hsa-miR-92b-5p |
2 |
accaaCCGTCCCA |
Disrupted |
N |
-0.56 |
| T |
hsa-miR-1302 hsa-miR-4298 |
2 2 |
accaacTGTCCCA accaacTGTCCCA |
Created Created |
N N |
-0.169 -0.169 |
|||
| 160564029 | rs186342339 | A | A |
hsa-miR-579-3p hsa-miR-592 hsa-miR-597-5p hsa-miR-616-3p hsa-miR-664b-3p |
1 1 1 1 1 |
CAAATGAcacagg caaaTGACACAgg caaaTGACACAgg caAATGACAcagg CAAATGAcacagg |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
0.105 -0.052 -0.02 0.047 0.115 |
| G |
hsa-miR-1227-3p hsa-miR-1914-5p hsa-miR-6889-3p |
1 1 1 |
caaaTGGCACAgg caaatgGCACAGG caaatGGCACAGg |
Created Created Created |
N N N |
-0.053 -0.094 -0.107 |
|||
| 160564908 | rs7725289 | A | A |
hsa-miR-4438 hsa-miR-5095 hsa-miR-600 hsa-miR-7151-3p |
1 1 2 1 |
GCCTGTAagccaa GCCTGTAAgccaa gcCTGTAAGccaa GCCTGTAAgccaa |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.126 -0.291 -0.057 -0.26 |
| G |
hsa-miR-24-3p hsa-miR-4284 hsa-miR-513a-5p hsa-miR-8057 |
3 2 1 3 |
gcctgTGAGCCAa gcctGTGAGCCAa gCCTGTGAgccaa gcctgtGAGCCAA |
Created Created Created Created |
N N N N |
-0.116 -0.299 -0.077 -0.116 |
|||
| 160565119 | rs192812944 | G | G |
hsa-miR-4445-3p hsa-miR-548al |
0 |
agTGCCGTAagtt agTGCCGTAagtt |
Disrupted Disrupted |
N N |
-0.212 -0.236 |
| A |
hsa-miR-183-5p hsa-miR-8074 |
0 |
aGTGCCATAagtt agtGCCATAAgtt |
Created Created |
N N |
-0.347 -0.145 |
|||
| 160565180 | rs144882680 | C | C |
hsa-miR-1537-3p |
1 |
tcaaatCGGTTTA |
Disrupted |
N |
-0.163 |
| T |
hsa-miR-497-3p |
1 |
tcaaatTGGTTTA |
Created |
N |
-0.048 |