SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
	Home	Search	Help	Download

Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_006407
Gene Symbol:	ARL6IP5
Description:	Homo sapiens ADP-ribosylation-like factor 6 interacting protein 5 (ARL6IP5), mRNA.
Gene Location:	chr3(+):69134089-69155239
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.69105994T>C			ICGC_468894		TCGA-CM-6674-01A-11D-1835-10		ColonAdenocarcinoma(TCGA,US)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-144-5p	agTGATATCCccatgactt	4	GGAUAUCA	m8a	(m7a->m8a)	-0.249	-0.093	-0.45
hsa-miR-3689a-5p	agtgATATCACcatgactt	4	UGUGAUAU	m7b	Disrupted	-0.112	no TS	2.26
hsa-miR-3689b-5p	agtgATATCACcatgactt	4	UGUGAUAU	m7b	Disrupted	-0.112	no TS	2.26
hsa-miR-3689e	agtgATATCACcatgactt	4	UGUGAUAU	m7b	Disrupted	-0.112	no TS	2.26
hsa-miR-3689f	agtgATATCACcatgactt	4	UGUGAUAU	m7b	Disrupted	-0.131	no TS	2.5

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
69105994	rs1052137	C	A	hsa-miR-144-5p hsa-miR-3689a-5p hsa-miR-3689b-5p hsa-miR-3689e hsa-miR-3689f	4 4 4 4 4	GATATCAccatga gATATCACcatga gATATCACcatga gATATCACcatga gATATCACcatga	Created Created Created Created Created	N N N N N	-0.156 -0.112 -0.112 -0.112 -0.131
			C	hsa-miR-4450 hsa-miR-6857-5p	4 4	gatATCCCCAtga gatATCCCCAtga	Disrupted Disrupted	N N	-0.192 -0.253

Genome Browser