SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001011722
Gene Symbol: ARHGEF10L
Description: Homo sapiens Rho guanine nucleotide exchange factor (GEF) 10-like (ARHGEF10L), transcript variant 2, mRNA.
Gene Location: chr1(+):17907047-18024370
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr1:g.17697430A>G COSN9367522 C0056T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1204 accaaGGCCACGcccggct
0 UCGUGGCC m7b Disrupted -0.278000 no TS 1.790000
hsa-miR-1268a accaaggcCACGCCCGgct
0 CGGGCGUG m8a Disrupted -0.463000 -0.245000 0.720000
hsa-miR-1268b accaaggcCACGCCCGgct
0 CGGGCGUG m8a Disrupted -0.463000 -0.245000 0.720000
hsa-miR-3178 accaaggcCGCGCCCggct
0 GGGGCGCG m7b Created no TS -0.242000 -5.080000
hsa-miR-4479 accaagGCCGCGCccggct
0 CGCGCGGC m7b Created no TS -0.305000 -3.840000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.17697816T>C COSN8636947 J76_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7a-2-3p taaagtCTGTACAtattgg
12
CUGUACAG m7b Disrupted -0.233000 no TS 0.110000
hsa-let-7g-3p taaagtCTGTACAtattgg
12
CUGUACAG m7b Disrupted -0.233000 no TS 2.860000
hsa-miR-143-5p taaagtCTGCACatattgg
0 GGUGCAGU m6b Created no TS -0.176000 -0.130000
hsa-miR-3166 taaaGTCTGCacatattgg
0 CGCAGACA m6b Created no TS -0.204000 -0.010000
hsa-miR-4771 taaAGTCTGCacatattgg
0 AGCAGACU m7b (m6b->m7b) no TS -0.526000 0.350000
hsa-miR-499b-5p taAAGTCTGTacatattgg
10
ACAGACUU m8a (m8a->m7a) -0.259000 -0.231000 1.310000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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