SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_015071
Gene Symbol: ARHGAP26
Description: Homo sapiens Rho GTPase activating protein 26 (ARHGAP26), transcript variant 2, mRNA.
Gene Location: chr5(+):142150291-142608572
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr5:g.143222460C>T COSN9409050 AOCS-159-1-9 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-148b-5p gggccccagCAGAACTgct
 0 AAGUUCUG m7b (m7b->m6c) 0.000000 0.050000 No effect
hsa-miR-3168 gggccccagTAGAACTgct
 0 GAGUUCUA m7b (m6c->m7b) no TS 0.000000 No effect
hsa-miR-3692-5p gggccCCAGCAGaactgct
 7
 CCUGCUGG m7b Disrupted 0.000000 -0.083000 No effect
hsa-miR-4667-5p gggCCCCAGTagaactgct
 2
 ACUGGGGA m7a (m6a->m7a) 0.148000 0.148000 No effect
hsa-miR-4731-5p gggCCCCAGCAgaactgct
 1
 UGCUGGGG m8a Disrupted -0.019000 -0.024000 No effect
hsa-miR-5589-5p gggcCCCAGCagaactgct
 1
 GGCUGGGU m6b Disrupted -0.042000 -0.037000 No effect
hsa-miR-637 gggCCCCAGTagaactgct
 2
 ACUGGGGG m7a (m6a->m7a) -0.015000 -0.015000 No effect
hsa-miR-93-3p gggcccCAGCAGaactgct
 7
 ACUGCUGA m6b Disrupted 0.000000 -0.428000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143224119T>G COSN6510517 HX20T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3613-3p ttttTTTTTTGaaaagata
 12
 ACAAAAAA m7b Disrupted 1.076000 0.979000 0.010000
hsa-miR-607 tttttttTTTGAAaagata
 2
 GUUCAAAU m6b Disrupted 0.662000 0.541000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143224468G>C COSN2073882 RK180_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3923 gcctactTACTAGTaagat
 2
 AACUAGUA m7b Created 0.118000 0.115000 -1.150000
hsa-miR-628-3p gcctacTTACTAGtaagat
 0 UCUAGUAA m7b Created no TS -0.001000 -2.270000


Mutation Mutation ID Sample Name Cancer Type
chr5:g.143224856A>G COSN14867125 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr5:g.143225059C>T COSN7878186 8061105 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4719 aggttagATTTGTGAacct
 2
 UCACAAAU m8a Created 0.159000 0.358000 -4.100000
hsa-miR-4762-5p aggttAGATTTGtgaacct
 5
 CCAAAUCU m7b Created 0.201000 0.288000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143225226G>T ICGC_BA634994-2A78-11E2-9C69-1CFD496BB9B8 CPCG_0103_Pr_P_P3 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1285-3p tcactctgtTGCCCAGgct
 0 UCUGGGCA m7b (m6c->m7b) -0.017 -0.079 -4.73
hsa-miR-196a-3p tcactcTGTTGCCcaggct
 0 CGGCAACA m7b Created -0.335 -0.282 -0.02
hsa-miR-3187-5p tcactctgtTGCCCAGGct
 0 CCUGGGCA m8a (m7b->m8a) -0.008 -0.014 -0.01
hsa-miR-4726-5p tcactctgTGGCCCaggct
 0 AGGGCCAG m6b Disrupted -0.034 -0.013 No effect
hsa-miR-5189 tcactctgtTGCCCAGgct
 0 UCUGGGCA m7b (m6c->m7b) -0.036 -0.023 No effect
hsa-miR-612 tcactctgtTGCCCAGgct
 0 GCUGGGCA m7b (m6c->m7b) 0.002 0.005 No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143225373A>G ICGC_C26AB140-2A78-11E2-BDED-1EFD496BB9B8 CPCG_0103_Pr_P_P4 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3675-3p tttttagTAGAGATGgggt
 0 CAUCUCUA m8a Created no TS 0.106 -0.01
hsa-miR-4684-5p tttttaGTAGAGAtggggt
 0 CUCUCUAC m7b Created no TS 0.003 -0.95

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143225463C>A ICGC_7958BC86-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-619 gctgggatTCCAGGTgtga
 0 GACCUGGA m7b Disrupted -0.05 -0.066 No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143225607T>C COSN14789107 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3926 ctgtagacaTTTGGCCcca
 1
 UGGCCAAA m7b (m7b->m6c) 0.029000 no TS No effect
hsa-miR-4480 ctgtagacACTTGGCccca
 8
 AGCCAAGU m7b Created -0.267000 -0.187000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143225612C>T COSN6865813 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3619-3p gacattTGGTCCCagcttc
 0 GGGACCAU m7a Created NA NA No effect
hsa-miR-3649 gacatttGGTCCCagcttc
 0 AGGGACCU m6b Created no TS -0.078000 -2.170000
hsa-miR-3926 gacaTTTGGCCccagcttc
 1
 UGGCCAAA m7b Disrupted 0.029000 no TS No effect
hsa-miR-4731-5p gacatttggCCCCAGCttc
 1
 UGCUGGGG m7b (m7b->m6c) -0.019000 0.014000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143226004C>T COSN14763690 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-18a-3p actttAGGGCAGatgagga
 3
 ACUGCCCU m7b Disrupted -0.137000 no TS 0.070000
hsa-miR-18b-3p actTTAGGGCAgatgagga
 2
 UGCCCUAA m8a Disrupted -0.120000 no TS 0.060000
hsa-miR-3157-3p acttTAGGGCAGatgagga
 2
 CUGCCCUA m8a Disrupted -0.082000 no TS No effect
hsa-miR-324-3p actttaGGGCAGatgagga
 3
 ACUGCCCC m6b Disrupted -0.049000 no TS No effect
hsa-miR-452-3p actttagggCAGATGAGga
 2
 CUCAUCUG m8a (m8a->m7b) 0.142000 0.064000 0.010000
hsa-miR-874 actttAGGGCAGatgagga
 0 CUGCCCUG m7a Disrupted NA NA 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143226181C>T COSN7878187 8015127 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1283 acaaaatTTTGTAGctaaa
 0 UCUACAAA m7b Created no TS 0.068000 No effect
hsa-miR-187-5p acaaaattTTGTAGCtaaa
 6
 GGCUACAA m7b Created -0.017000 -0.032000 No effect
hsa-miR-221-3p acaaaatttTGTAGCTaaa
 6
 AGCUACAU m7a (m6b->m7a) 0.011000 0.011000 No effect
hsa-miR-222-3p acaaaatttTGTAGCTaaa
 6
 AGCUACAU m7a (m6b->m7a) 0.004000 0.004000 No effect
hsa-miR-4282 acaAAATTTTgtagctaaa
 3
 UAAAAUUU m7b (m6b->m7b) 0.267000 0.502000 No effect
hsa-miR-548v acaaaatttTGTAGCTaaa
 6
 AGCUACAG m7a (m6b->m7a) 0.009000 0.009000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143226224A>G ICGC_CF8A12BC-2A78-11E2-951E-21FD496BB9B8 CPCG_0103_Pr_P_P5 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1295b-3p ctcacGCCTATaatcccag
 0 AAUAGGCC m6b Disrupted -0.46 -0.472 No effect
hsa-miR-3937 ctcaCGCCTGTaatcccag
 0 ACAGGCGG m7a Created NA NA No effect
hsa-miR-4438 ctcacGCCTGTaatcccag
 0 CACAGGCU m6b Created 0.067 0.104 No effect
hsa-miR-5095 ctcacGCCTGTAAtcccag
 0 UUACAGGC m8a Created 0.095 0.15 -4.36

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143226304A>C 0_204 Prostate cancer
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-193b-5p gacggtgAAACCCCGtctc
 2
 CGGGGUUU m8a Disrupted 0.047 no TS No effect
hsa-miR-4787-5p gacggtgaACCCCCGtctc
 2
 GCGGGGGU m7b Created no TS -0.145 No effect
hsa-miR-5096 gacGGTGAAACcccgtctc
 1
 GUUUCACC m8a Disrupted 0.31 0.164 0.01

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143226736C>A COSN14778266 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4302 gtcagacCACACTGtcttt
 0 CCAGUGUG m7b Disrupted -0.098000 -0.126000 0.030000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143227406T>C COSN14755262 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1253 caggatgTCTTCTCaccca
 2
 AGAGAAGA m7b Disrupted 0.174000 0.029000 0.030000
hsa-miR-3617 caggATGTCTTctcaccca
 0 AAAGACAU m7b Disrupted 0.157000 no TS No effect
hsa-miR-5004-5p caggaTGTCCTCtcaccca
 1
 UGAGGACA m7b Created -0.042000 -0.010000 No effect
hsa-miR-641 caggATGTCTTctcaccca
 0 AAAGACAU m7b Disrupted 0.167000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143227671G>C COSN15453657 AOCS-086-1-5 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-297 aaggcCATACAatccaggt
 0 AUGUAUGU m6b Created no TS 0.088000 No effect
hsa-miR-3149 aaggcCATACAAtccaggt
 1
 UUUGUAUG m7b Created 0.117000 0.311000 No effect
hsa-miR-4320 aaggccatAGAATCCaggt
 6
 GGGAUUCU m7b Disrupted -0.352000 -0.329000 No effect
hsa-miR-508-3p aaggccaTACAATCcaggt
 1
 UGAUUGUA m7b Created 0.022000 0.059000 No effect
hsa-miR-675-3p aaggcCATACAatccaggt
 0 CUGUAUGC m6b Created no TS 0.063000 -1.100000
hsa-miR-297 aaggcCATACAatccaggt
 0 AUGUAUGU m6b Created no TS 0.088000 No effect
hsa-miR-3149 aaggcCATACAAtccaggt
 1
 UUUGUAUG m7b Created 0.117000 0.311000 No effect
hsa-miR-4320 aaggccatAGAATCCaggt
 6
 GGGAUUCU m7b Disrupted -0.352000 -0.329000 No effect
hsa-miR-508-3p aaggccaTACAATCcaggt
 1
 UGAUUGUA m7b Created 0.022000 0.059000 No effect
hsa-miR-675-3p aaggcCATACAatccaggt
 0 CUGUAUGC m6b Created no TS 0.063000 -1.100000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143227873T>C COSN4843971 tumor_4135350 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][Burkitt_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4677-3p aaaaagcgaTCACAGAaaa
 6
 UCUGUGAG m7a (m7a->m6b) -0.009000 no TS 1.320000
hsa-miR-4679 aaaaagcgATCACAGAaaa
 0 UCUGUGAU m8a Disrupted -0.057000 no TS 0.190000
hsa-miR-4790-5p aaAAAGCGATcacagaaaa
 0 AUCGCUUU m8a (m8a->m7a) -0.188000 -0.160000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.143228381C>T COSN7878188 8033471 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3183 caAGAGAGGCtgtggatgg
 5
 GCCUCUCU m8a (m8a->m7a) -0.088000 -0.115000 -0.010000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
143223065 rs2107626 C C hsa-miR-1253
hsa-miR-6770-5p
2
2
 agTCTTCTCAtgc
agtCTTCTCAtgc
 Disrupted
Disrupted
N
N
 -0.085
-0.006
T hsa-miR-548u
hsa-miR-7161-5p
3
3
 AGTCTTTtcatgc
AGTCTTTtcatgc
 Created
Created
N
N
 0.001
0.02
143224120 rs200634903 G G hsa-miR-1305
hsa-miR-3613-3p
hsa-miR-607
hsa-miR-627-3p
1
1
1
7
 ttttTTGAAAAga
TTTTTTGAaaaga
tttTTTGAAAaga
ttttttGAAAAGA
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 0.115
0.198
0.126
0.089
143224161 rs187486968 T T hsa-miR-4659a-5p
hsa-miR-4659b-5p
hsa-miR-4776-3p
hsa-miR-5590-5p
9
9
9
9
 actatATGGCAAa
actatATGGCAAa
actatATGGCAAA
actaTATGGCAAa
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 -0.032
-0.032
-0.064
-0.102
G hsa-miR-18b-3p
hsa-miR-3157-3p
hsa-miR-874-3p
9
9
9
 actaTAGGGCAaa
actaTAGGGCAAa
actatAGGGCAAa
 Created
Created
Created
N
N
N
 -0.11
-0.189
-0.069
143225607 rs853158 C T hsa-miR-3926
1
 tagacaTTTGGCC
 Created
N
 0.029
C hsa-miR-4480
hsa-miR-6513-3p
2
2
 tagacACTTGGCc
tagACACTTGgcc
 Disrupted
Disrupted
N
N
 0.08
0.169
143226004 rs187729 T C hsa-miR-18a-3p
hsa-miR-18b-3p
hsa-miR-1913
hsa-miR-3157-3p
hsa-miR-324-3p
hsa-miR-452-3p
3
2
3
2
3
2
 ttAGGGCAGAtga
TTAGGGCAgatga
ttaGGGCAGAtga
tTAGGGCAgatga
ttaGGGCAGAtga
ttagggCAGATGA
 Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
 -0.137
-0.12
-0.049
-0.082
-0.049
0.078
143226048 rs189831760 C C hsa-miR-1343-3p
hsa-miR-4640-5p
hsa-miR-4726-5p
hsa-miR-6508-3p
hsa-miR-6742-3p
hsa-miR-6783-3p
hsa-miR-6852-5p
hsa-miR-939-3p
2
2
2
2
2
2
2
2
 catggCCCAGGAt
caTGGCCCAggat
caTGGCCCAggat
cATGGCCCAggat
catggCCCAGGAt
catggCCCAGGAt
catggCCCAGGAt
catgGCCCAGGAt
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
N
 0.055
-0.01
-0.013
-0.048
0.004
0.046
0.014
-0.061
A hsa-miR-1227-3p
hsa-miR-1914-5p
hsa-miR-4659a-5p
hsa-miR-4659b-5p
hsa-miR-6889-3p
2
2
2
2
2
 caTGGCACAggat
catgGCACAGGAt
CATGGCAcaggat
CATGGCAcaggat
catGGCACAGgat
 Created
Created
Created
Created
Created
N
N
N
N
N
 0.005
-0.051
0.056
0.056
-0.081
143226181 rs9324910 C
T hsa-miR-1283
hsa-miR-187-5p
hsa-miR-4282
1
1
1
 aaatTTTGTAGct
aaattTTGTAGCt
AAATTTTgtagct
 Created
Created
Created
N
N
N
 0.068
-0.015
0.235
143226325 rs33954372 - C hsa-miR-129-5p
hsa-miR-3149
1
1
 aaaataCAAAAAA
aaaATACAAAaaa
 Unknown
Unknown
N
N
 0.196
0.117
-
143226736 rs154787 A C hsa-miR-4302
0 agacCACACTGtc
 Created
N
 0.028
A hsa-miR-133a-3p
hsa-miR-133b
hsa-miR-6843-3p
hsa-miR-6848-3p
0 aGACCAAActgtc
aGACCAAActgtc
AGACCAAactgtc
AGACCAAactgtc
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 0.015
0.015
0.004
0.007
143226885 rs17100180 A A hsa-miR-1285-3p
hsa-miR-3187-5p
hsa-miR-326
hsa-miR-330-5p
hsa-miR-378g
hsa-miR-4486
hsa-miR-5189-5p
hsa-miR-612
hsa-miR-6860
2
2
2
2
2
2
2
2
2
 tTGCCCAGAgctg
tTGCCCAGAgctg
ttgCCCAGAGctg
ttgCCCAGAGctg
ttGCCCAGAgctg
ttGCCCAGAgctg
tTGCCCAGAgctg
tTGCCCAGAgctg
tTGCCCAGAgctg
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
N
N
 -0.029
-0.029
0.029
0.038
0.006
-0.018
-0.029
-0.019
-0.019
G hsa-miR-6736-3p
0 ttgcccGGAGCTG
 Created
N
 0.077
143227406 rs154786 C T hsa-miR-1253
hsa-miR-3617-5p
hsa-miR-641
hsa-miR-6770-5p
1
0
0
1
 gatgTCTTCTCAc
gATGTCTTctcac
gATGTCTTctcac
gatgtCTTCTCAc
 Created
Created
Created
Created
N
N
N
N
 0.145
0.157
0.167
0.097
C hsa-miR-5004-5p
1
 gaTGTCCTCtcac
 Disrupted
N
 0.032

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