SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_006305
Gene Symbol: ANP32A
Description: Homo sapiens acidic (leucine-rich) nuclear phosphoprotein 32 family, member A (ANP32A), mRNA.
Gene Location: chr15(-):69070874-69113261
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr15:g.68778596A>G COSN5756207 HX28T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-338-5p gtttgtcgTATTGTaaaaa
 3
 AACAAUAU m6b Disrupted -0.041000 no TS 1.120000
hsa-miR-3529-3p gtttgtcgTGTTGTaaaaa
 1
 AACAACAA m6b Created 0.033000 -0.066000 -2.056000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.68779295G>C COSN15073537 LP6005690-DNA_A02 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2054 aaaaTATTACAacgctttg
 0 CUGUAAUA m7b Created no TS -0.097000 -0.370000
hsa-miR-576-5p aaaatATTAGAAcgctttg
 7
 AUUCUAAU m7b Disrupted -0.049000 -0.042000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr15:g.68779656A>C COSN1683116 RK108_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-138-5p gggctgagCACCAGCcata
 7
 AGCUGGUG m7b Disrupted -0.148000 no TS -0.010000
hsa-miR-185-3p gggctgAGCCCCagccata
 0 AGGGGCUG m6b Created no TS -0.144000 No effect
hsa-miR-24-3p gggCTGAGCCccagccata
 0 UGGCUCAG m7b (m6c->m7b) -0.084000 -0.142000 -0.010000
hsa-miR-3907 gggctGAGCACCagccata
 6
 AGGUGCUC m7b Disrupted -0.355000 no TS 4.710000
hsa-miR-4283 gggctGAGCCCCAgccata
 0 UGGGGCUC m8a Created no TS -0.362000 -5.410000
hsa-miR-4437 gggcTGAGCCCcagccata
 0 UGGGCUCA m7b Created no TS -0.094000 -0.020000
hsa-miR-4505 gggctgagcCCCAGCCata
 7
 AGGCUGGG m7b (m6b->m7b) -0.117000 -0.310000 -4.450000
hsa-miR-4731-5p gggctgagCCCCAGCcata
 0 UGCUGGGG m7b Created no TS -0.167000 No effect
hsa-miR-548q gggctgaGCACCAGCcata
 6
 GCUGGUGC m8a Disrupted -0.412000 -0.245000 No effect
hsa-miR-5589-5p gggctgagcCCCAGCCata
 0 GGCUGGGU m7a (m6a->m7a) NA NA -1.350000
hsa-miR-138-5p gggctgagCACCAGCcata
 7
 AGCUGGUG m7b Disrupted -0.148000 no TS -0.010000
hsa-miR-185-3p gggctgAGCCCCagccata
 0 AGGGGCUG m6b Created no TS -0.144000 No effect
hsa-miR-24-3p gggCTGAGCCccagccata
 0 UGGCUCAG m7b (m6c->m7b) -0.084000 -0.142000 -0.010000
hsa-miR-3907 gggctGAGCACCagccata
 6
 AGGUGCUC m7b Disrupted -0.355000 no TS 4.710000
hsa-miR-4283 gggctGAGCCCCAgccata
 0 UGGGGCUC m8a Created no TS -0.362000 -5.410000
hsa-miR-4437 gggcTGAGCCCcagccata
 0 UGGGCUCA m7b Created no TS -0.094000 -0.020000
hsa-miR-4505 gggctgagcCCCAGCCata
 7
 AGGCUGGG m7b (m6b->m7b) -0.117000 -0.310000 -4.450000
hsa-miR-4731-5p gggctgagCCCCAGCcata
 0 UGCUGGGG m7b Created no TS -0.167000 No effect
hsa-miR-548q gggctgaGCACCAGCcata
 6
 GCUGGUGC m8a Disrupted -0.412000 -0.245000 No effect
hsa-miR-5589-5p gggctgagcCCCAGCCata
 0 GGCUGGGU m7a (m6a->m7a) NA NA -1.350000
hsa-miR-138-5p gggctgagCACCAGCcata
 7
 AGCUGGUG m7b Disrupted -0.148000 no TS -0.010000
hsa-miR-185-3p gggctgAGCCCCagccata
 0 AGGGGCUG m6b Created no TS -0.144000 No effect
hsa-miR-24-3p gggCTGAGCCccagccata
 0 UGGCUCAG m7b (m6c->m7b) -0.084000 -0.142000 -0.010000
hsa-miR-3907 gggctGAGCACCagccata
 6
 AGGUGCUC m7b Disrupted -0.355000 no TS 4.710000
hsa-miR-4283 gggctGAGCCCCAgccata
 0 UGGGGCUC m8a Created no TS -0.362000 -5.410000
hsa-miR-4437 gggcTGAGCCCcagccata
 0 UGGGCUCA m7b Created no TS -0.094000 -0.020000
hsa-miR-4505 gggctgagcCCCAGCCata
 7
 AGGCUGGG m7b (m6b->m7b) -0.117000 -0.310000 -4.450000
hsa-miR-4731-5p gggctgagCCCCAGCcata
 0 UGCUGGGG m7b Created no TS -0.167000 No effect
hsa-miR-548q gggctgaGCACCAGCcata
 6
 GCUGGUGC m8a Disrupted -0.412000 -0.245000 No effect
hsa-miR-5589-5p gggctgagcCCCAGCCata
 0 GGCUGGGU m7a (m6a->m7a) NA NA -1.350000
hsa-miR-138-5p gggctgagCACCAGCcata
 0 AGCUGGUG m7b Disrupted -0.148 no TS -0.01
hsa-miR-185-3p gggctgAGCCCCagccata
 0 AGGGGCUG m6b Created no TS -0.144 No effect
hsa-miR-24-3p gggCTGAGCCccagccata
 0 UGGCUCAG m7b (m6c->m7b) -0.084 -0.142 -0.01
hsa-miR-3907 gggctGAGCACCagccata
 0 AGGUGCUC m7b Disrupted -0.355 no TS 4.71
hsa-miR-4283 gggctGAGCCCCAgccata
 0 UGGGGCUC m8a Created no TS -0.362 -5.41
hsa-miR-4437 gggcTGAGCCCcagccata
 0 UGGGCUCA m7b Created no TS -0.094 -0.02
hsa-miR-4505 gggctgagcCCCAGCCata
 0 AGGCUGGG m7b (m6b->m7b) -0.117 -0.31 -4.45
hsa-miR-4731-5p gggctgagCCCCAGCcata
 0 UGCUGGGG m7b Created no TS -0.167 10.05
hsa-miR-548q gggctgaGCACCAGCcata
 0 GCUGGUGC m8a Disrupted -0.412 -0.245 No effect
hsa-miR-5589-5p gggctgagcCCCAGCCata
 0 GGCUGGGU m7a (m6a->m7a) NA NA -1.35

Mutation Mutation ID Sample Name Cancer Type
chr15:g.68779982T>C COSN4762918 tumor_4189998 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][Burkitt_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
68778647 rs58983340 G G hsa-miR-3136-3p
hsa-miR-328-3p
hsa-miR-7155-3p
2
3
2
 aagTTGGGCCAac
aagttGGGCCAAc
aagTTGGGCCAac
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.47
-0.225
-0.438
A hsa-miR-24-3p
hsa-miR-4284
hsa-miR-8057
3
3
3
 aagtTGAGCCAac
aagtTGAGCCAac
aagttGAGCCAAc
 Created
Created
Created
N
N
N
 -0.146
-0.148
-0.166

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