SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001204056
Gene Symbol: ANKRD12
Description: Homo sapiens ankyrin repeat domain 12 (ANKRD12), transcript variant 2, mRNA.
Gene Location: chr18(+):9137560-9285983
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr18:g.9281825A>G COSN9845659 C0063T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4742-3p aaacttttaAATACAGcat
2
UCUGUAUU m7b (m7b->m6c) -0.091000 no TS 0.010000
hsa-miR-4799-5p aaactTTTAGATacagcat
1
AUCUAAAU m7a Created 0.250000 0.250000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr18:g.9283178G>T COSN15535809 AOCS-064-1-6 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-146a-3p agaaaaTCAGAGaggggta
3
CCUCUGAA m6b Disrupted 0.034000 no TS 1.990000
hsa-miR-29a-5p agaAAATCAGagaggggta
1
ACUGAUUU m7b (m7b->m6b) 0.178000 0.043000 0.490000
hsa-miR-301a-5p agaaaaTCAGAGaggggta
3
GCUCUGAC m6b Disrupted 0.029000 no TS 0.030000
hsa-miR-3183 agaaaatcAGAGAGGggta
3
GCCUCUCU m7b Disrupted -0.002000 no TS 2.610000
hsa-miR-3920 agaaAATCAGagaggggta
0 ACUGAUUA m6b Disrupted 0.048000 -0.014000 0.130000
hsa-miR-4723-3p agaaaatcAGAGAGGGgta
3
CCCUCUCU m8a Disrupted -0.002000 no TS 0.070000
hsa-miR-146a-3p agaaaaTCAGAGaggggta
3
CCUCUGAA m6b Disrupted 0.034000 no TS 1.990000
hsa-miR-29a-5p agaAAATCAGagaggggta
1
ACUGAUUU m7b (m7b->m6b) 0.178000 0.043000 0.490000
hsa-miR-301a-5p agaaaaTCAGAGaggggta
3
GCUCUGAC m6b Disrupted 0.029000 no TS 0.030000
hsa-miR-3183 agaaaatcAGAGAGGggta
3
GCCUCUCU m7b Disrupted -0.002000 no TS 2.610000
hsa-miR-3920 agaaAATCAGagaggggta
0 ACUGAUUA m6b Disrupted 0.048000 -0.014000 0.130000
hsa-miR-4723-3p agaaaatcAGAGAGGGgta
3
CCCUCUCU m8a Disrupted -0.002000 no TS 0.070000


Mutation Mutation ID Sample Name Cancer Type
chr18:g.9283544T>A COSN5183496 PD4109a [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr18:g.9283692C>T COSN5183497 PD4005a [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4773 caattTGTTCTaaatatct
16
CAGAACAG m6b Disrupted 0.024000 no TS 0.040000
hsa-miR-5687 caatttGTTCTAAatatct
16
UUAGAACG m7a Disrupted -0.009000 no TS 1.500000

Mutation Mutation ID Sample Name Cancer Type
chr18:g.9283696A>G COSN1759902 RK046_C02 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3145-3p ttgttctAAATATCTgttt
0 AGAUAUUU m8a Disrupted 0.263000 0.191000 0.010000
hsa-miR-374c-3p ttgttCTAAGTatctgttt
0 CACUUAGC m6b Created -0.074000 -0.069000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr18:g.9283696A>T COSN9845660 C0089T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3145-3p ttgttctAAATATCTgttt
0 AGAUAUUU m8a Disrupted 0.263000 0.191000 -0.080000

Mutation Mutation ID Sample Name Cancer Type
chr18:g.9283696A>G ICGC_sm173842 RK046_C02 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3145-3p ttgttctAAATATCTgttt
0 AGAUAUUU m8a Disrupted 0.263 0.191 -0.43
hsa-miR-374c-3p ttgttCTAAGTatctgttt
0 CACUUAGC m6b Created -0.074 -0.069 No effect

Mutation Mutation ID Sample Name Cancer Type
chr18:g.9283849A>C COSN1210289 HX12T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
9282697 rs186459932 G
C hsa-miR-3145-3p
hsa-miR-4330
8
12
AAATATCtgagga
aaatATCTGAGga
Created
Created
N
N
0.162
-0.019
9283177 rs148576201 - AG hsa-miR-146a-3p
hsa-miR-29a-5p
hsa-miR-301a-5p
hsa-miR-3183
hsa-miR-3920
hsa-miR-3921
hsa-miR-4653-5p
hsa-miR-4723-3p
hsa-miR-6769b-3p
hsa-miR-6817-3p
3
3
3
3
3
3
3
3
3
3
gaaaaTCAGAGAggg
gaAAATCAGAgaggg
gaaaaTCAGAGAggg
gaaaatcAGAGAGGg
gaaAATCAGAgaggg
gaaaaTCAGAGAggg
gaaaaTCAGAGAggg
gaaaatcAGAGAGGg
gaaaatcAGAGAGGg
gaaaatCAGAGAGgg
Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
N
N
N
N
N
N
N
N
N
N
0.034
-0.006
0.029
-0.002
-0.003
0.032
0.036
-0.002
0.007
-0.02
- hsa-miR-2276-5p
3
gaaaatCAGAGGG
Unknown
N
-0.108
9283699 rs76177498 T T hsa-miR-3145-3p
2
tAAATATCtgttt
Disrupted
N
0.072
C hsa-miR-4678
2
taAATACCTgttt
Created
N
-0.031
9284604 rs7228251 T T hsa-miR-3145-3p
5
aAAATATCttgta
Disrupted
N
0.06
C hsa-miR-4678
hsa-miR-624-3p
5
4
aaAATACCTtgta
aaaatACCTTGTA
Created
Created
N
N
-0.047
-0.109

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