SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_152363
Gene Symbol: ANKLE1
Description: Homo sapiens ankyrin repeat and LEM domain containing 1 (ANKLE1), mRNA.
Gene Location: chr19(+):17392453-17398454
Browse Associations

Somatic mutations that impact miRNA target sites




Mutation Mutation ID Sample Name Cancer Type
chr19:g.17286656G>T COSN8992570 PTC-14C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr19:g.17286670G>T COSN8992571 PTC-7C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr19:g.17286672G>T COSN8992573 PTC-7C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr19:g.17286674G>T COSN8992576 PTC-14C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr19:g.17286690G>T COSN8992577 PTC-6C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr19:g.17286692T>G COSN8992578 PTC-28C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr19:g.17287168C>T COSN7355443 8067211 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3937 ggtggctcaCGCCTGTaat
0 ACAGGCGG m7a (m7a->m6b) NA NA 5.380000
hsa-miR-4514 ggtggctcaTGCCTGTaat
0 ACAGGCAG m7a (m6b->m7a) NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr19:g.17287180T>C ICGC_E0C4EFB6-2A78-11E2-B303-24FD496BB9B8 CPCG_0103_Pr_P_P6 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-204-3p ctgtaaTCCCAGCattttg
0 GCUGGGAA m7a Created -0.258 -0.258 -1.51
hsa-miR-3146 ctgtaatcCTAGCATtttg
0 CAUGCUAG m7b Disrupted -0.218 -0.126 1.69
hsa-miR-3159 ctgTAATCCTAgcattttg
1
UAGGAUUA m8a Disrupted -0.085 no TS 2.99
hsa-miR-5089 ctgtAATCCCAgcattttg
0 GUGGGAUU m7b Created -0.055 -0.099 No effect
hsa-miR-5589-5p ctgtaatCCCAGCattttg
0 GGCUGGGU m6b Created no TS -0.133 -0.08

Mutation Mutation ID Sample Name Cancer Type
chr19:g.17287585C>T COSN8256862 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3714 agccCTGCCTTgtctatgg
0 GAAGGCAG m7b Created no TS -0.146000 No effect
hsa-miR-4436b-3p agccCTGCCCTGtctatgg
1
CAGGGCAG m8a Disrupted -0.172000 no TS 3.460000
hsa-miR-4524b-3p agccctgcCCTGTCTatgg
1
GAGACAGG m7b Disrupted -0.350000 no TS 3.470000
hsa-miR-4763-3p agCCCTGCCTtgtctatgg
1
AGGCAGGG m8a (m7a->m8a) -0.249000 -0.276000 0.720000
hsa-miR-940 agcCCTGCCTTgtctatgg
0 AAGGCAGG m8a Created no TS -0.177000 3.680000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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