SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000668
Gene Symbol: ADH1B
Description: Homo sapiens alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B), mRNA.
Gene Location: chr4(-):100227526-100242572
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr4:g.99306522A>T COSN7720589 8033414 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-323a-3p tagacaTAATGTaaaatag
 0 CACAUUAC m6b Created no TS -0.056000 0.600000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.99306716A>G COSN5547188 RK172_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4422 cctgtgttaATGCTTTgtt
 4
 AAAAGCAU m7b (m7b->m6b) -0.301000 -0.174000 -1.770000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.99306893A>T COSN5049897 HX34T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-137 aacaccttaAGCAATAtat
 3
 UUAUUGCU m7b (m7b->m6b) -0.160000 no TS 1.860000
hsa-miR-25-3p aacaccttaTGCAATatat
 2
 CAUUGCAC m6b Created -0.086000 -0.154000 -1.330000
hsa-miR-363-3p aacaccttaTGCAATatat
 2
 AAUUGCAC m6b Created -0.096000 -0.168000 -1.220000
hsa-miR-367-3p aacaccttaTGCAATatat
 2
 AAUUGCAC m6b Created -0.107000 -0.179000 -0.010000
hsa-miR-4720-3p aacacCTTAAGCAatatat
 2
 UGCUUAAG m8a Disrupted -0.227000 no TS 7.380000
hsa-miR-4804-3p aacaccTTAAGCAatatat
 2
 UGCUUAAC m7a Disrupted -0.067000 no TS 5.370000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.99307331C>A COSN1975941 RK041_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-627 atAGACTCACatttacaag
 3
 GUGAGUCU m8a (m8a->m7b) -0.150000 -0.287000 0.120000
hsa-miR-627 atAGACTCACatttacaag
 0 GUGAGUCU m8a (m8a->m7b) -0.15 -0.287 0.12

Mutation Mutation ID Sample Name Cancer Type
chr4:g.99307358G>T COSN9004893 8051720 [pancreas][NS][carcinoid-endocrine_tumour][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3140-3p ggggtAAAAGCTagggtaa
 0 AGCUUUUG m7a Disrupted NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr4:g.99307404C>A COSN9897244 C0057T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4282 cactgtcgAAATTTTcctt
 0 UAAAAUUU m7b Created no TS 0.110000 -0.010000
hsa-miR-513a-3p cactgtcGAAATTTtcctt
 2
 UAAAUUUC m7b Created 0.109000 0.149000 -1.110000
hsa-miR-513c-3p cactgtcGAAATTTtcctt
 2
 UAAAUUUC m7b Created 0.109000 0.149000 -1.610000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.99307540T>A COSN5049898 HX21T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-224-5p cctGTGACTTcttgcattt
 3
 CAAGUCAC m7b (m7b->m6c) -0.164000 no TS 0.900000
hsa-miR-5697 cctgtgaCTACTTGcattt
 0 UCAAGUAG m7b Created no TS -0.163000 -3.770000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.99307541T>G COSN5049899 HX21T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-224-5p tcctGTGACTTcttgcatt
 3
 CAAGUCAC m7b Disrupted -0.164000 no TS 0.900000
hsa-miR-4696 tcctgtgacGTCTTGCAtt
 6
 UGCAAGAC m8a (m7a->m8a) -0.123000 -0.339000 -4.300000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.99307796T>A COSN15448396 AOCS-164-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1224-5p agccTCCTCAaccctacaa
 0 GUGAGGAC m6b Created no TS -0.105000 0.650000
hsa-miR-197-5p agcctccTCTACCCtacaa
 2
 CGGGUAGA m7b Disrupted -0.212000 no TS 4.000000
hsa-miR-296-3p agcctcctCAACCCTacaa
 0 GAGGGUUG m7b Created no TS -0.462000 -9.260000
hsa-miR-3132 agcctccTCTACCCtacaa
 2
 UGGGUAGA m7b Disrupted -0.221000 no TS 4.000000
hsa-miR-3150b-3p agcCTCCTCAaccctacaa
 0 UGAGGAGA m7a (m6b->m7a) no TS -0.127000 -1.000000
hsa-miR-3916 agccTCCTCTaccctacaa
 4
 AAGAGGAA m6b Disrupted -0.084000 no TS 0.010000
hsa-miR-4451 agcctcCTCTACCctacaa
 2
 UGGUAGAG m7b Disrupted -0.194000 no TS 8.710000
hsa-miR-4689 agcCTCCTCAAccctacaa
 0 UUGAGGAG m8a Created no TS -0.290000 -10.230000
hsa-miR-4784 agcCTCCTCAaccctacaa
 0 UGAGGAGA m7a (m6b->m7a) no TS -0.137000 -1.000000
hsa-miR-877-5p agccTCCTCTACcctacaa
 4
 GUAGAGGA m8a Disrupted -0.108000 no TS 1.200000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
99307285 rs3211503 C
T hsa-miR-4282
hsa-miR-5009-3p
3
22
 AAATTTTttagga
aaatttTTTAGGA
 Created
Created
N
N
 0.119
-0.047

Genome Browser