SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_006988
Gene Symbol: ADAMTS1
Description: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 1 (ADAMTS1), mRNA.
Gene Location: chr21(-):28208605-28217728
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr21:g.26836405T>G COSN9155142 AOCS-137-3-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4803 catatTTATGTTtatacat
 16
 UAACAUAA m7b Created -0.120000 -0.314000 No effect
hsa-miR-548c-3p catatttATTTTTatacat
 20
 CAAAAAUC m6b Disrupted -0.009000 -0.040000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr21:g.26836895T>G COSN9155143 AOCS-149-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5585-3p tgtattTATTCAagtgcat
 1
 CUGAAUAG m6b Disrupted -0.004000 no TS 0.040000

Mutation Mutation ID Sample Name Cancer Type
chr21:g.26836936G>A COSN7142380 8052570 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-466 tctttattTGTGTAattca
 6
 AUACACAU m6b Disrupted -0.049000 no TS 0.810000
hsa-miR-4719 tctttATTTGTGtaattca
 5
 UCACAAAU m7b Disrupted -0.078000 no TS 0.020000
hsa-miR-4731-3p tctttatTTGTGTaattca
 6
 CACACAAG m6b Disrupted -0.162000 -0.131000 0.010000
hsa-miR-4801 tctttatTTGTGTAattca
 6
 UACACAAG m7a Disrupted -0.173000 -0.131000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr21:g.26837485G>T COSN5768512 HCC167 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1243 gcgtatcttTCCAGTaacc
 0 AACUGGAU m6b Created no TS -0.142000 -2.560000
hsa-miR-193a-3p gcgtatcttGCCAGTaacc
 1
 AACUGGCC m6b Disrupted -0.173000 no TS No effect
hsa-miR-193b-3p gcgtatcttGCCAGTaacc
 1
 AACUGGCC m6b Disrupted -0.173000 no TS 0.190000
hsa-miR-31-5p gcgtaTCTTGCCagtaacc
 2
 AGGCAAGA m7b Disrupted -0.405000 no TS 5.580000
hsa-miR-3128 gcgtatcTTGCCAGtaacc
 2
 UCUGGCAA m7b Disrupted -0.162000 no TS 0.020000
hsa-miR-3654 gcgtatcttTCCAGTaacc
 0 GACUGGAC m6b Created no TS -0.142000 No effect
hsa-miR-3978 gcgtatCTTTCCAgtaacc
 0 GUGGAAAG m7b Created no TS -0.143000 No effect
hsa-miR-4799-3p gcgtatctTGCCAGTaacc
 0 ACUGGCAU m7a Disrupted NA NA 0.010000
hsa-miR-5588-5p gcgtatctTGCCAGTaacc
 0 ACUGGCAU m7a Disrupted NA NA 0.030000
hsa-miR-875-3p gcgtatcTTTCCAGtaacc
 0 CCUGGAAA m7b Created no TS -0.108000 No effect
hsa-miR-892b gcgtatcttGCCAGTaacc
 1
 CACUGGCU m6b Disrupted -0.180000 no TS No effect
hsa-miR-1243 gcgtatcttTCCAGTaacc
 0 AACUGGAU m6b Created no TS -0.142000 -2.560000
hsa-miR-193a-3p gcgtatcttGCCAGTaacc
 1
 AACUGGCC m6b Disrupted -0.173000 no TS No effect
hsa-miR-193b-3p gcgtatcttGCCAGTaacc
 1
 AACUGGCC m6b Disrupted -0.173000 no TS 0.190000
hsa-miR-31-5p gcgtaTCTTGCCagtaacc
 2
 AGGCAAGA m7b Disrupted -0.405000 no TS 5.580000
hsa-miR-3128 gcgtatcTTGCCAGtaacc
 2
 UCUGGCAA m7b Disrupted -0.162000 no TS 0.020000
hsa-miR-3654 gcgtatcttTCCAGTaacc
 0 GACUGGAC m6b Created no TS -0.142000 No effect
hsa-miR-3978 gcgtatCTTTCCAgtaacc
 0 GUGGAAAG m7b Created no TS -0.143000 No effect
hsa-miR-4799-3p gcgtatctTGCCAGTaacc
 0 ACUGGCAU m7a Disrupted NA NA 0.010000
hsa-miR-5588-5p gcgtatctTGCCAGTaacc
 0 ACUGGCAU m7a Disrupted NA NA 0.030000
hsa-miR-875-3p gcgtatcTTTCCAGtaacc
 0 CCUGGAAA m7b Created no TS -0.108000 No effect
hsa-miR-892b gcgtatcttGCCAGTaacc
 1
 CACUGGCU m6b Disrupted -0.180000 no TS No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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