| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
||||||||
| Home | Search | Help | Download | |||||
| RefSeq ID: | NM_000789 |
|---|---|
| Gene Symbol: | ACE |
| Description: | Homo sapiens angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 (ACE), transcript variant 1, mRNA. |
| Gene Location: | chr17(+):61554421-61575741 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr17:g.63497630G>A | COSN8603591 | 3402_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-376c |
tctgagTCTATGTccctca |
0 | AACAUAGA | m7b | Created | no TS | -0.019000 |
-0.160000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr17:g.63497766A>C | COSN9319844 | AOCS-086-1-5 | [ovary][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-185-3p |
tgcccCAGCCCCTcctggc |
0 | AGGGGCUG | m8a | Created | -0.398000 | -0.523000 |
-2.720000 |
| hsa-miR-3184-5p |
tgccccaGCCCCTCctggc |
0 | UGAGGGGC | m7b | Created | no TS | -0.146000 |
-1.940000 |
| hsa-miR-3689d |
tgccccagCACCTCCtggc |
1 |
GGGAGGUG | m7b | Disrupted | -0.241000 | -0.182000 |
1.450000 |
| hsa-miR-423-5p |
tgccccaGCCCCTCctggc |
0 | UGAGGGGC | m7b | Created | no TS | -0.155000 |
-0.020000 |
| hsa-miR-4492 |
tgccCCAGCCCCtcctggc |
3 |
GGGGCUGG | m8a | Created | -0.690000 | -0.770000 |
-0.020000 |
| hsa-miR-4498 |
tgccCCAGCCCctcctggc |
3 |
UGGGCUGG | m7b | Created | -0.743000 | -0.842000 |
-0.080000 |
| hsa-miR-4505 |
tgcCCCAGCCcctcctggc |
0 | AGGCUGGG | m7b | (m6b->m7b) | -0.253000 | -0.326000 | No effect |
| hsa-miR-4731-5p |
tgCCCCAGCAcctcctggc |
2 |
UGCUGGGG | m8a | (m8a->m7a) | -0.712000 | -0.535000 | No effect |
| hsa-miR-4779 |
tgccccagcCCCTCCTggc |
0 | UAGGAGGG | m7b | (m6c->m7b) | no TS | -0.018000 |
-0.020000 |
| hsa-miR-5001-5p |
tgccCCAGCCCctcctggc |
3 |
AGGGCUGG | m7b | Created | -0.741000 | -0.840000 |
-0.370000 |
| hsa-miR-762 |
tgccCCAGCCCCtcctggc |
3 |
GGGGCUGG | m8a | Created | -0.795000 | -0.866000 |
-0.480000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr17:g.63497875G>A | COSN9319845 | AOCS-117-3-3 | [ovary][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-2115-5p |
ggactctgGGAAGCagaca |
5 |
AGCUUCCA | m6b | Disrupted | -0.077000 | no TS |
0.080000 |
| hsa-miR-3160-5p |
ggactctgGAAAGCagaca |
0 | GGCUUUCU | m6b | Created | no TS | -0.011000 |
-6.130000 |
| hsa-miR-3180-5p |
ggacTCTGGAAagcagaca |
0 | CUUCCAGA | m7b | Created | no TS | -0.122000 |
-2.700000 |
| hsa-miR-520a-5p |
ggaCTCTGGAaagcagaca |
0 | CUCCAGAG | m7b | (m6b->m7b) | no TS | -0.189000 |
-2.090000 |
| hsa-miR-525-5p |
ggaCTCTGGAaagcagaca |
0 | CUCCAGAG | m7b | (m6b->m7b) | no TS | -0.189000 |
-2.370000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr17:g.63497998G>A | COSN14514747 | 8067938 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |